ACADIA Pharmaceuticals

Senior Manager, AI Engineering

ACADIA Pharmaceuticals$150K — $187K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's or PhD in Data Science, Statistics, Computer Science, Mathematics, Engineering, or related field.
  • 5+ years of relevant experience or 2+ years with a PhD in AI or machine learning.
  • Proficiency in Python, SQL, and frameworks such as PyTorch or TensorFlow.
  • Experience with Generative AI technologies and vector databases.
  • Knowledge of ML Ops practices for deployment and monitoring.
  • Understanding of responsible AI principles and compliance in regulated environments.
  • Ability to travel as needed.

Responsibilities

  • Contribute to enterprise AI strategy by aligning initiatives with business goals.
  • Develop solutions that leverage AI and machine learning for business value.
  • Deliver actionable insights through data analytics and science use cases.
  • Support AI governance through technical expertise and best practices.
  • Assess feasibility and risks of proposed AI initiatives for prioritization.
  • Design and deploy machine learning models using established ML Ops practices.
  • Monitor emerging AI developments to inform AI solution design.

Benefits

  • Competitive base salary and discretionary bonus.
  • Medical, dental, and vision insurance.
  • 401(k) with a fully vested company match.
  • Employee Stock Purchase Plan with purchase price lock-in.
  • 15+ vacation days and 10 days of sick leave.
  • Paid parental leave and tuition assistance.
Full Job Description

Please note that this position can be based in San Diego, CA, San Francisco, CA or Princeton, NJ. Acadia's hybrid model requires this role to work in our office three days per week on average.

Position Summary

The Senior Manager, AI Engineering plays a key role in advancing Acadia's enterprise AI capabilities through the development, deployment, and governance of scalable AI and machine learning solutions. As part of the Artificial Intelligence team, this individual will partner with stakeholders across R&D, Commercial, and Corporate functions to translate data into actionable insights and business value. This role will help drive AI strategy execution, support responsible AI practices, and enable the adoption of innovative technologies that accelerate decision-making and operational excellence across the organization.

Primary Responsibilities
  • Contribute to the execution of the enterprise AI strategy and roadmap by aligning AI and machine learning initiatives with business priorities and identifying high-value use cases across the organization
  • Partner with stakeholders across R&D, Commercial, and Corporate Functions to identify and develop AI and machine learning solutions that drive business value
  • Deliver analytics and data science use cases that generate actionable insights and support data-driven decision-making
  • Support cross-functional AI governance activities by providing technical expertise on model risk, responsible AI practices, and lifecycle management
  • Assess the technical feasibility, business value, and implementation risks of proposed AI and data science initiatives to support prioritization and investment decisions
  • Design, develop, validate, deploy, and support machine learning models, statistical analyses, and scalable ML/LLM pipelines using established ML Ops and LLM Ops practices
  • Evaluate, implement, and optimize GenAI technologies, including large language models, vector databases, model endpoints, agent frameworks, and guardrail solutions aligned with enterprise architecture standards
  • Maintain model, prompt, and dataset documentation, ensuring lineage, auditability, governance compliance, approvals, and adherence to enterprise AI system-of-record standards
  • Develop reusable data science frameworks, reference implementations, and technical standards that accelerate AI adoption, scalability, and operational efficiency across the enterprise
  • Partner with Information Technology, Data Insights & Analytics, and Information Security teams to support AI platforms, infrastructure capabilities, technology selection, vendor assessments, and RFI/RFP evaluations
  • Apply AI governance and responsible AI standards, including model lifecycle management, bias and robustness testing, explainability, human oversight, incident response, and regulatory compliance requirements
  • Support compliance with applicable GxP requirements and evolving AI regulations, including alignment with frameworks such as NIST AI RMF and EU AI Act readiness standards
  • Contribute to AI enablement initiatives through knowledge sharing, technical documentation, practitioner education, portfolio reviews, and cross-functional collaboration that promotes responsible AI adoption
  • Monitor emerging AI, machine learning, and regulatory developments to inform solution design, platform evolution, and enterprise AI capabilities
  • Provide technical recommendations on AI solution architecture, platform strategy, and build-versus-buy decisions
  • Other duties as assigned

Education/Experience/Skills
  • Master's degree in Data Science, Statistics, Computer Science, Mathematics, Engineering, or a related quantitative discipline with 5+ years of relevant experience; OR PhD in a related quantitative discipline with 2+ years of industry experience or equivalent advanced research experience in machine learning, artificial intelligence, or data science
  • Experience developing, deploying, and supporting machine learning and AI solutions in production or research environments
  • Proficiency in Python, SQL, and AI/ML frameworks such as PyTorch, TensorFlow, or scikit-learn
  • Experience working with Generative AI technologies, large language models, retrieval-augmented generation (RAG), vector databases, and agent frameworks
  • Experience with ML Ops or LLM Ops practices, including version control, model evaluation, monitoring, and deployment workflows
  • Knowledge of responsible AI principles, model explainability, evaluation methodologies, and AI governance concepts
  • Experience working within regulated or compliance-focused environments preferred
  • Ability to travel domestically and internationally as needed

Physical Requirements

This role involves regular standing, walking, sitting, and the use of hands for handling or operating equipment. The employee may also need to reach, climb, balance, stoop, kneel, crouch, and maintain visual, verbal, and auditory communication in a standard office environment and while working independently from remote locations. The employee must occasionally lift and/or move up to 20 pounds. This position requires the ability to travel independently overnight and/or work after hours as required by travel schedules or business needs.

#LI-HYBRID

#LI-CS1

In addition to a competitive base salary, this position is also eligible for discretionary bonus and equity awards based on factors such as individual and organizational performance. Actual amounts will vary depending on experience, performance, and location.

Salary Range

$150,300-$187,900 USD

What we offer US-based Employees:
  • Competitive base, bonus, new hire and ongoing equity packages
  • Medical, dental, and vision insurance
  • Employer-paid life, disability, business travel and EAP coverage
  • 401(k) Plan with a fully vested company match 1:1 up to 5%
  • Employee Stock Purchase Plan with a 2-year purchase price lock-in
  • 15+ vacation days
  • 13 -15 paid holidays, including office closure between December 24th and January 1st
  • 10 days of paid sick time
  • Paid parental leave benefit
  • Tuition assistance

About ACADIA Pharmaceuticals

ACADIA Pharmaceuticals is a biopharmaceutical company focused on the development and commercialization of innovative medicines to address unmet medical needs in central nervous system (CNS) disorders. The company's lead product, Nuplazid (pimavanserin), is the first and only FDA-approved treatment for hallucinations and delusions associated with Parkinson's disease psychosis. ACADIA's pipeline includes product candidates for the treatment of schizophrenia, dementia-related psychosis, and major depressive disorder. The company was founded in 1993 and is headquartered in San Diego, California.
Learn more about ACADIA Pharmaceuticals
Size
500 employees
Market Cap
$2.5 billion
Industry
Net Income
-$281.5 million
Founded
1993
5 Year Trend
+94.6%
Revenue
$441.7 million
NASDAQ

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