Dyne Therapeutics

Senior Lab Manager

Dyne Therapeutics$143K — $175K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in life science required.
  • 5+ years of experience in a BL2 wet lab; 8 years total experience desired.
  • Strong interpersonal skills with cross-functional collaboration ability.
  • Experience with vendor management and service provider coordination.
  • Operational knowledge of lab equipment and troubleshooting capabilities.
  • Current DOT and IATA certifications preferred.
  • Ability to lift 50 lbs and perform physical tasks as needed.

Responsibilities

  • Ensure laboratory equipment is functioning and coordinate maintenance activities.
  • Manage service contracts and arrange maintenance visits with vendors.
  • Oversee EHS compliance, including chemical disposal and PPE enforcement.
  • Serve on IACUC and manage controlled substances in the vivarium.
  • Coordinate with IT to maintain lab technology and software.
  • Train new hires and provide safety orientation for lab users.
  • Support domestic and international shipments as necessary.

Benefits

  • Collaborative work environment emphasizing safety and integrity.
  • Opportunity for professional growth in a high-paced lab setting.
  • Access to advanced lab equipment and technology.
  • Dynamic role requiring cross-departmental collaboration.
Full Job Description
Role Summary:

The Senior Lab Manager works with the Lab Operations Associate Director to provide a smoothly operating laboratory for our scientific personnel. This individual needs to be willing to learn, adapt and be able to perform at a high level in a fast-paced environment.

This role is based in Waltham, MA without the possibility of being a remote role.

Primary Responsibilities Include:
  • Ensure that all laboratory equipment is properly functioning; coordinate preventative maintenance, repairs, calibrations, purchase of equipment, and coordinate training as needed
  • Manage and coordinate the maintenance agreements/service contracts for lab equipment and arranging timely maintenance visits working with lab operation associate, scientists and vendors
  • Oversee all aspects of EHS, including tracking/managing and disposal of chemicals and hazardous/non-hazardous materials, enforcing PPE policy, assist with oversight and management of contract EHS and lab support, maintain permits, participate in and contribute to the IBC and Safety Committee
    • Support EHS activities related to facilities (fire drills, First Aid Kits, AEDs)
    • Serve as the Chemical Hygiene Officer
  • Serve as a member of the IACUC and an authorized key holder to the lockbox of controlled substances in the vivarium
  • Coordinate with IT to ensure computers, data collection software and associated equipment are functioning in the lab
  • Work with managers of new hires to coordinate training and provide safety orientation for new lab personnel and visitors to the lab.
  • Coordinate and support incoming/outgoing domestic and international shipments as needed
  • Monitoring of gases to support cryo freezers and equipment
  • ELN management, coordinate training as needed, and the use of other software applications
  • Interface with Facilities team to maintain the infrastructure serving the labs such as HVAC, exhaust systems, gases, utilities, etc.
  • Must be willing to come in off hours to resolve lab emergencies if needed
  • Work with functional areas to generate standing orders as needed, and maintain managed inventories of consumables and reagents

Education and Skills Requirements:
  • Bachelor's degree in life science with 5+ years of experience in an industry BL2 wet lab; and 8 years total experience.
  • Experience working with external vendors and service providers.
  • Ability to effectively prioritize, shift gears, and execute tasks based on business need.
  • Excellent decision making, communication and collaboration skills in a cross-functional and multi-level environment demonstrating very strong interpersonal skills
  • Experience with Electronic Notebook applications, LIMS, and databases
  • Ability to influence without authority and lead by example
  • Ability to self-evaluate work for accuracy and completeness
  • Experience with budget management, contract negotiation, and vendor management
  • Operational knowledge of and troubleshooting capabilities for common lab equipment
  • Takes initiative and exhibits independence in identifying and addressing short and long-term opportunities for optimization of lab processes
  • Current DOT and IATA certifications preferred
  • Must be able to lift 50 lbs. (this is the weight of one dry ice box) from the floor to approximately bench height
  • Must be able to sit, stand, walk, bend, stretch and don appropriate PPE for prolonged periods as needed

#LI-Onsite

MA Pay Range

$143,000-$175,000 USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

About Dyne Therapeutics

Dyne Therapeutics is a biotechnology company that is focused on developing therapies for patients with genetically driven muscle diseases. The company is developing a platform that is designed to deliver nucleic acids to muscle tissue. Dyne's lead product candidate is DYN101, which is a treatment for patients with myotonic dystrophy type 1 (DM1). DM1 is a genetic disorder that affects the muscles and other body systems. DYN101 is designed to reduce the levels of toxic RNA that are produced by the mutated gene that causes DM1. The company was founded in 2018 and is headquartered in Cambridge, Massachusetts.
Learn more about Dyne Therapeutics
Size
70 employees
Market Cap
$633.4 million
Industry
NASDAQ

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