What You Will Achieve This laboratory-based position is in the Analytical Development group within Vaccines. The primary functions of this role are to develop analytical assays in support of the extensive vaccine portfolio and to support the Critical Reagents tasks. The individual will collaborate closely with scientists across the Early BioProcess Development (EBPD) to design and implement cell-based potency assays for multiple vaccine programs. The individual will participate in regular vaccine development meetings and represent the group on multidisciplinary teams.
How You Will Achieve It- Provide laboratory-based support for assay development, including ELISA and cell-based assays to support potency assay development.
- Perform in-vitro expression analysis of mRNA Drug Substance (DS) and Drug Products (DP) for multiple RNA vaccine programs.
- Support sample testing for process development, formulation development, critical reagents characterization and on-going stability studies.
- Analyze data using appropriate statistical software, such as GraphPad Prism and SoftMax
- Support the Critical Reagents qualification testing, delivery, and documentation
- Document experiments, data, and conclusions in an electronic lab notebook (ELN) contemporaneously.
- Contribute to authoring technical documents, including development reports, analytical lab methods, and method qualification reports.
- Review scientific and technical literature to stay current in the field.
- Present data in meetings within the department
Qualifications:Must-Have- BS degree in biological science, microbiology, immunology, or related fields with 2+ years relevant laboratory experience; OR a master's degree with more than 0+ years of experience.
- Background and experience in mammalian cell culture, DNA and RNA transfection, and reporter cell assays.
- Experience with ELISA assay.
- Experience with in vitro expression and flow cytometry.
- Knowledge of innate and acquired immunity, with the ability to apply this knowledge to test novel adjuvants.
- Proficiency in analytical software, including GraphPad Prism and SoftMax.
- Proficiency in computer skills including Microsoft Word, PowerPoint, and Excel.
- Strong organization skills
- Strong verbal and written communication skills.
Nice-to-Have:- Experience with authoring development reports and lab methods
- Experience in documenting experiments using Signals electronic lab notebook
PHYSICAL/MENTAL REQUIREMENTS- Ability to work 40 hours/week in a laboratory setting
- Ability to perform data analysis
Work Location Assignment: On Premise
The annual base salary for this position ranges from $68,600.00 to $114,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine ActPfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
Research and Development
