BristolMyers Squibb

Senior Application Engineer

BristolMyers Squibb$137K — $166K *
Information Technology
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or higher degree in Computer Science, Engineering, Science, or a related field.
  • 5+ years of experience in software engineering or cloud engineering with a focus on backend application development.
  • Hands-on experience building cloud-native applications on AWS with familiarity in various AWS services.
  • Strong proficiency in backend frameworks like Python/FastAPI, TypeScript/Node, or similar.
  • Experience with CI/CD, automated testing, and infrastructure-as-code tools such as Terraform or AWS CDK.
  • Familiarity with AI application frameworks like LangGraph or similar tools.
  • Excellent communication skills and a collaborative mindset in an agile environment.

Responsibilities

  • Design, build, and operate backend services and APIs for AI Accelerator products.
  • Develop and integrate AI services using Python and TypeScript frameworks.
  • Execute AI sprint cycles to develop, test, and validate AI product increments.
  • Implement secure patterns for authentication, authorization, and data management.
  • Build integrations for agent workflows and enterprise capabilities using AWS services.
  • Maintain and enhance CI/CD pipelines and infrastructure for cloud AI applications.
  • Collaborate with cross-functional teams to address delivery challenges and refine project priorities.

Benefits

  • Comprehensive health and wellness plans for employees and their families.
  • Flexible work schedule with hybrid work options.
  • Opportunities for professional development and continuous learning.
  • Collaborative and innovative work environment focused on cutting-edge AI technology.
  • Access to advanced AI tools and resources specific to the pharmaceutical industry.
Full Job Description

Summary:

As a Senior Application Engineer within Bristol Myers Squibb's AI Venture Studio delivery team, you will be a hands-on senior individual contributor responsible for building secure cloud-hosted applications including, but not limited to, agentic AI products and cross functional knowledge and context infrastructure. You will design APIs, services, infrastructure patterns, deployment pipelines, semantic-layer evolution patterns for agent context engineering, and agent runtimes that allow AI Accelerator pods to move quickly without giving up reliability, observability, security, or enterprise alignment.

The role is deeply tied to the AI Accelerator delivery model: six two-week sprints over a 12-week cycle to build, test, validate, and prepare MVPs for scaling in a fully agile model. You will leverage the latest technologies to address pharma-specific unsolved problems across R&D, Commercialization, Manufacturing, and Enabling Functions, where critical context is buried in unstructured knowledge files, multimodal documents and reports, operational records, scientific evidence packages, and other evolving knowledge sources.

BMS is an AWS-first engineering environment for these products, so you will default to AWS-native services and patterns while integrating BMS-preferred AI tools such as LangGraph, FastMCP, OpenSearch, Amazon S3 Vectors, Amazon Neptune, PostgreSQL/RDS, Redis, AWS Fargate, LangSmith, and a variety of approved frontier LLM models and APIs.

This is a role for someone excited to work hands-on with the latest AI tools and frontier technologies, pushing the limits of what technology can do to help BMS discover, develop, and deliver innovative medicines.


Key Responsibilities:

Cloud-Native Application and API Engineering:
  • Design, build, and operate backend services, APIs, and application components that power AI Accelerator products.

  • Develop Python/FastAPI, TypeScript/Node, or similar services that integrate LLM APIs, retrieval systems, workflow engines, and internal enterprise systems.

  • Execute AI Accelerator cycles of six two-week sprints over a 12-week cycle by developing, testing, and validating cloud and agentic AI product increments.

  • Develop MCP-accessible services that allow approved agents to read, write, search, and maintain structured (e.g. markdown/YAML) knowledge assets.

  • Build MCP/FastMCP read-write-search APIs, permissioned knowledge stores, version control, audit trails, access controls, and integrations with AWS-native storage and identity patterns.

  • Implement secure application patterns for authn/authz, BMS SSO, BMS Cloud Creds, secrets management, auditability, input validation, and safe service boundaries.

  • Partner with frontend engineers to define clean API contracts, streaming response patterns, error handling, and service-level behaviors for AI-powered user experiences.

Agent Runtime, Retrieval, and AWS Platform Patterns:
  • Build and host agentic workflows using LangGraph, including workflow state, multi-agent orchestration, tool execution, fan-out/fan-in patterns, and durable checkpoints.

  • Develop MCP tool integrations and FastMCP servers that allow agents to use governed enterprise capabilities safely and consistently.

  • Implement retrieval, memory, and context services using AWS-aligned data stores such as S3, Athena, PostgreSQL/RDS, ElastiCache/Redis, OpenSearch, Amazon S3 Vectors, and Amazon Neptune.

  • Build and evolve the semantic layer for SQL and other natural-language-to-code generating agents, enabling novel analytical questions to be grounded in query history, column values, warehouse context, explicit instructions, memory, and governed data tools.

  • Package reusable deployment patterns, starter kits, and golden paths for AWS Fargate, serverless services, containers, and production-adjacent AI applications.

DevOps, Infrastructure, Observability, and Evaluation:
  • Create and maintain CI/CD pipelines, environment configuration, automated tests, infrastructure-as-code, and release processes for cloud AI applications.

  • Instrument application reliability, latency, cost, usage, tracing, and model/agent behavior using enterprise observability and AI evaluation tools such as LangSmith or similar platforms.

  • Embed automated quality gates, security scans, regression tests, structured output validation gates, and responsible AI guardrail checks into delivery pipelines.

  • Build sandboxed agent execution environments where code and data can branch together, transformations are recoverable, provenance is preserved, and merge/audit workflows protect shared data assets.

  • Demonstrate MVP progress through bi-weekly demos and technical updates, tracking platform performance, reliability, cost, security, and business-value signals to assess readiness for scaling.

  • Continuously improve shared platform patterns based on lessons learned across pods, changing enterprise standards, and advances in AI engineering practices.

Collaboration, Enablement, and Technical Leadership:
  • Partner with AI Engineers, Data Engineers, Data Scientists, Frontend Engineers, Pod Leads, architects, and product teams to solve complex delivery challenges.

  • Continuously refine delivery priorities and technical backlog items based on stakeholder feedback, performance results, sprint reviews, and lessons learned throughout MVP development.

  • Help complete MVP transition activities by maturing AI capabilities, adding key features, validating reliability in practice, confirming business value, and assessing production readiness.

  • Provide technical coaching through design reviews, code reviews, architecture reviews, incident learning, documentation, and reusable examples.

  • Communicate cloud trade-offs clearly, including when to optimize for speed, cost, reliability, compliance, scalability, or long-term maintainability.


Qualifications & Experience:

  • Bachelor's or higher degree in Computer Science, Engineering, Science, or a related field.

  • 5+ years of experience in software engineering, cloud engineering, platform engineering, or backend application development with increasing responsibility.

  • Hands-on experience building cloud-native applications on AWS; familiarity with services such as S3, RDS/PostgreSQL, Athena, ElastiCache/Redis, OpenSearch, Fargate, Lambda, IAM, and VPC patterns.

  • Strong proficiency in Python, FastAPI, TypeScript/Node, or comparable backend application frameworks.

  • Experience with containers, CI/CD, GitHub-based workflows, automated testing, environment configuration, and infrastructure-as-code such as Terraform, AWS CDK, or CloudFormation.

  • Experience building LLM, RAG, or agentic AI applications using frameworks such as LangGraph, LangChain, PydanticAI, Claude Agent SDK, or similar tools.

  • Familiarity with MCP/FastMCP, read-write-search APIs, permissioned markdown/YAML stores, vector databases, knowledge graphs, session/state management, structured output validation gates, and evaluation-driven development.

  • Experience with SQL, semantic layers, data warehouse context, query history, and systems that translate LLM-derived meaning from unstructured scientific or operational sources into governed data/context layers.

  • Experience building sandboxed execution, data branching, provenance, version control, audit, and access-control patterns for agentic or data-intensive applications.

  • Practical experience integrating with model providers and a variety of approved frontier LLM models through enterprise AI services such as OpenAI, Anthropic, Gemini, AWS Bedrock, or similar approved channels.

  • Effective use of coding agents or AI-assisted development tools such as Claude Code, Codex, Gemini CLI, GitHub Copilot, or similar tools.

  • Excitement for experimenting with the latest AI tools and technologies while turning frontier prototypes into reliable foundations that help discover, develop, and deliver innovative medicines.

  • Curious and inquisitive mindset, with strong communication skills and comfort operating in fast-moving, cross-functional agile teams.

#AICP

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

About BristolMyers Squibb

BristolMyers Squibb Careers

Join the vibrant team at BristolMyers Squibb, a leader in global biopharmaceutical innovation, where your career growth is as important as the life-changing solutions we develop. At BristolMyers Squibb, we are committed to fostering a diverse and inclusive workplace that encourages professional growth and development. Work You’ll Do Embark on a career with BristolMyers Squibb and be part of a company that’s dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. With us, you’ll contribute to a culture that embraces scientific innovation, responsible leadership, and community outreach. Explore job opportunities in various fields from research to marketing, and join a team that values leadership and diversity. Our commitment to career growth means we support your journey with extensive training programs, leadership development opportunities, and a global, diverse network of professionals. Innovative Work At BristolMyers Squibb, innovation is at the core of everything we do. From pioneering research in oncology to breakthroughs in immunology, our professionals have the opportunity to make significant contributions to the field and impact lives globally. Our collaborative environment encourages team members to challenge the status quo and bring forward ideas that pave the way for groundbreaking solutions. Be Part of a Great Team Working at BristolMyers Squibb means being part of a team that supports your aspirations and shares your values. Our culture thrives on teamwork, respect, and diversity, creating a workplace where everyone can achieve their potential. Enjoy the benefits of being part of a company that values work-life balance, provides competitive benefits, and fosters an environment where skills and leadership are developed through hands-on experience and comprehensive mentorship programs. Future-Proof Your Career With a multitude of job opportunities ranging from internships to full-time positions, BristolMyers Squibb is not just hiring; we’re building futures. We equip our employees with the tools needed for success, including advanced training in diverse skill sets, leadership programs, and opportunities for professional networking and growth. Stay Connected Join Our Team Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference. Explore our career portal for all current job listings and be sure to submit your resume. Keep Up to Date Stay informed with the latest company news, career tips, and industry insights from BristolMyers Squibb. Our careers blog is a resource for potential and current employees looking to maximize their career potential. Job Alert Emails Customize your subscription to receive job alerts and insider information tailored to your preferences. Discover the exciting and rewarding career opportunities that await at BristolMyers Squibb. At BristolMyers Squibb, your career is just the beginning – it’s a pathway to personal and professional fulfillment. Join us and make a global impact.
Learn more about BristolMyers Squibb
Size
32,200 employees
Market Cap
$156.3 billion
Industry
Net Income
-$9 billion
Founded
1887
5 Year Trend
+19%
Revenue
$42.5 billion
NASDAQ

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