Pfizer

Scientist, ADC In Vivo Pharmacology

Pfizer$79K — $132K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in biology, pharmacology, animal science, cancer biology, or related discipline with research experience.
  • Hands-on experience with rodent in vivo studies in various research settings.
  • Proficient in tumor implantation, measurement, animal monitoring, and documentation.
  • Understanding of oncology pharmacology concepts related to tumor growth and response assessment.
  • Ability to follow protocols carefully and address animal welfare concerns appropriately.
  • Strong attention to detail and organization across multiple projects.
  • Effective communication skills and teamwork in a scientific environment.
  • Technical expertise in moderately complex procedures under guidance.

Responsibilities

  • Execute in vivo oncology studies for ADC discovery using diverse models.
  • Perform advanced in vivo procedures such as tumor measurements and sample collection.
  • Support pharmacology studies to assess efficacy, tolerability, and pharmacodynamics.
  • Prepare and review study protocols and timelines to meet project goals.
  • Maintain compliant study records with electronic data systems.
  • Coordinate with various teams to ensure efficient study execution.
  • Assist in data review and initial interpretation of in vivo results.
  • Ensure adherence to IACUC protocols and biosafety requirements.

Benefits

  • Relocation support available.
  • Comprehensive health benefits including medical, dental, and vision coverage.
  • 401(k) plan with matching contributions and retirement savings options.
  • Paid vacation, holidays, and personal days.
  • Paid caregiver, parental, and medical leave.
Full Job Description
Scientist, ADC In Vivo Pharmacology

Position Responsibilities
  • Execute in vivo oncology studies supporting ADC discovery programs using a variety of in vivo models including syngeneic, cell line-derived, and patient-derived xenograft models as appropriate.
  • Perform routine and advanced in vivo procedures, including tumor measurements, body weight monitoring, test article administration, clinical observations, and sample collection.
  • Support ADC pharmacology studies assessing efficacy, tolerability, pharmacodynamic biomarkers, dose-response relationships, schedule optimization, and combination strategies.
  • Prepare, review, and follow study protocols, dosing schedules, randomization plans, and sample collection timelines in alignment with project goals and internal standards.
  • Maintain accurate, timely, and compliant study records using electronic data capture systems and approved documentation practices.
  • Coordinate with project line leads, vivarium operations, pathology, toxicology translational scientists, bioanalytical, pharmacodynamic and pharmacokinetic teams, and external partners to enable efficient study execution.
  • Assist with data quality review, graphical summaries, and preliminary interpretation of in vivo study results.
  • Ensure all work is conducted in accordance with IACUC protocols, animal welfare expectations, biosafety requirements, and Pfizer internal policies.

Minimum Qualifications / Key Skills
  • Bachelor's degree in biology, pharmacology, animal science, cancer biology, or a related discipline with relevant research experience.
  • Hands-on experience conducting rodent in vivo studies in an academic, biotechnology, pharmaceutical, or contract research setting.
  • Demonstrated proficiency with tumor implantation, tumor measurement, animal monitoring, dosing, sample collection, and study documentation.
  • Working knowledge of oncology pharmacology concepts, including tumor growth inhibition, response assessment, dose scheduling, tolerability, and pharmacodynamic endpoint collection.
  • Ability to follow protocols precisely, recognize technical or animal welfare concerns, and escalate issues appropriately.
  • Strong attention to detail, organizational skills, and ability to manage study activities across multiple concurrent programs.
  • Effective written and verbal communication skills and ability to work collaboratively in a matrixed scientific environment.
  • Applies technical expertise to moderately complex procedures and contributes to troubleshooting under guidance from senior scientists or in vivo study leads.
  • Demonstrates accountability for assigned study activities and contributes to team goals, timelines, and quality expectations.

Preferred Qualifications
  • Experience supporting ADC, targeted therapy, immuno-oncology, or combination oncology programs.
  • Familiarity with ADC-specific pharmacology considerations such as payload potency, linker stability, antigen expression, exposure-response relationships, and tolerability liabilities.
  • Experience with ex vivo tissue processing, biomarker sample collection, necropsy, flow cytometry sample preparation, or molecular endpoint workflows.
  • Familiarity with electronic data systems such as Studylog or similar in vivo study management platforms.
  • AALAS certification or equivalent training in animal care and use.

Relocation support available

Work Location Assignment: On Premise

The annual base salary for this position ranges from $79,400.00 to $132,400.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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