Research Specialist / Sr Scientist, Assay Sciences, Discovery Pharmacology

Altos Labs

$129K — $225K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or Master's degree with 8+ years industry experience (Research Specialist) or PhD with 6+ years post-PhD and 3+ years industry experience (Senior Scientist)
  • Extensive experience in developing and running diverse analytical and bioassays
  • Familiarity with advanced assay technologies such as MSD, HTRF, AlphaLISA
  • Proficiency in lab automation equipment like Bravo, Echo, and Digital Dispenser
  • Experience executing high-content imaging in 96- and 384-well formats
  • Demonstrated productivity and timeliness in work performance
  • Proven ability to manage external research partners (CROs)

Responsibilities

  • Develop the next generation of medicines through critical drug discovery efforts
  • Create, run, and optimize various cell-based and biochemical assays
  • Transform manual assays into efficient automated high-throughput screening processes
  • Ensure statistical rigor (Z'-factor) and scalability of assays
  • Engineer new assays from scratch to drive innovation
  • Maintain accurate experimental documentation in electronic lab notebooks (ELN)
  • Collaborate cross-functionally with Discovery Sciences, Computational Biology, and Product Development teams
  • Serve as the technical lead for the assay sciences team and oversee external CRO data quality

Benefits

  • Opportunities for professional growth in cutting-edge drug discovery
  • Impactful work in aging/rejuvenation biology
  • Collaborative environment with multidisciplinary teams
  • Access to advanced laboratory automation and assay technologies
  • Involvement in diverse drug development projects
Full Job Description
As a Research Specialist or Sr Scientist of Assay Sciences, Discovery Pharmacology team, your primary focus will be supporting the needs of development and operation of a wide range of analytical and bioassays within the Drug Discovery and Development (3DS) division of Altos. This is a laboratory research scientist position focused on the development and execution of cell-based and biochemical assays, and complex in vitro bioassays. Your work will contribute to our drug discovery campaigns across a diverse portfolio of discovery and development stage projects. Your expertise will be instrumental in driving our mission and making a significant impact in aging/rejuvenation biology and drug discovery. Responsibilities • You'll be right in the middle of drug discovery, developing the next generation of medicines. • Your main gig is making, running, and optimizing a ton of analytical and bioassays (cell-based, biochemical, complex in vitro). • You'll be taking manual assays and turning them into super-efficient, automated processes-think moving from a bench to high-throughput screening with automated gear. • You'll need to nail the stats (Z'-factor!) and make sure everything is scalable. • Creating new assays from scratch (de novo development) is also on the list. • Documenting everything in the electronic lab notebook (ELN) for awesome data integrity. • Working with other teams, including the Discovery Sciences, Institute of Computation and Product Development crew. • You'll be a technical lead for the assay sciences team. • You'll also be managing external research partners (CROs) to make sure their data is top-notch. Who You Are Required Qualifications • Research Specialist Experience Requirement: Bachelors or Masters degree and 8+ years of industry experience. • Sr Scientist Experience Requirements: PhD and 6+ years post-PhD, PLUS 3+ years of industry experience. • Seriously good at developing and running a huge variety of analytical and bioassays. • You should know your way around cutting-edge assay tech like MSD, HTRF, AlphaLISA, etc. • Expertise with lab automation gear is a must (Bravo, Echo, I.DOT, Digital Dispenser, etc.). • Experience with high-content imaging in high-throughput (96- and 384-well) formats. • You need to be a productive rockstar who can get work done on time. • Great at documenting your experiments in an ELN. • Proven experience managing external CROs. • Excellent communication and organizational skills-ready to multitask • An SME / emerging leader in a technical field with sustained performance and accomplishment. • Strong demonstrable expert knowledge of a specialized research area with a wide breadth of knowledge beyond a research specialty. • Demonstrates ability to apply excellent professional judgement and high proficiency of application of all skills and techniques relevant to lab / hub research projects. The salary range for Redwood City: • Research Specialist: $129,500 - $166,000 • Senior Scientist I, In Vitro Pharmacology $176,000 - $225,700 Exact compensation may vary based on skills, experience, and location. #LI-NN1 For UK applicants, before submitting your application: - Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice) - This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

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