Job Overview

As a Neuroscience Research Scientist for our Toxicology team located in Laval, you will be overseeing study conduct of preclinical efficacy and/or toxicology studies. Combined with neuroscience expertise and MRI-guided dosing responsibilities, the role expands to include scientific leadership in CNS models, technical oversight of neuroimaging, and precision delivery into the brain or CNS structures. Your success will ensure the smooth running of our research, as well as the integrity of our pre-clinical studies.

In this role, primary responsibilities include:

• Design and oversee with prospective and current clients MRI-guided targeting strategies for CNS delivery and support commercial groups in the preparation of statement of work;
• Perform MRI-guided dosing in collaboration with the surgeon team, ensure accurate placement to minimize off-target dose administration;
• Develop and optimize MRI protocols and targeting methodologies and contribute to innovation in CNS drug delivery techniques;
• Function as an independent Study Director in accordance with the applicable Good Laboratory Practice regulations (GLPs);
• Designs, writes, reviews and edits, as necessary, Study Plans, amendments and study schedules that define and schedule all study activities;
• Oversees and coordinates all aspects of study procedures, whether performed within the department or by service departments;
• Ensures that projects are performed according to Standard Operating Procedures and Good Laboratory Practice regulations and is aware of appropriate regulations, guidelines and guidances;
• Writes, reviews, and edits, as necessary, draft or final reports that document all study related procedures and results;
• Prompt verbal or written communication with Sponsors on study related business;
• Oversees and coordinates study conduct (MRI protocol and Study Plan development, technical guidance, and reporting).

Key Elements

We are looking for the following minimum qualifications for this role :

• Master's or Doctorate in Neuroscience or any other related discipline;
• At least 3 years of relevant experience in a Scientist position;
• Experience related to MRI (Magnetic Resonance Imaging) and theoretical & practical knowledge of the subject are preferred;
• MRI-related targeting dosing is an asset;
• Good interpersonal and communication skills;
• Strong problem-solving skills.

Role Specific Information:

• Location: 445 Boul. Armand-Frappier, Laval, QC, H7V 4B3;
• Transportation: Free parking. Near the Montmorency Subway. Electric vehicle charging station;
• Annual bonus based on performance;
• Schedule: Monday to Friday, 8:00 am to 4:15 pm;
• Hybrid position - half on-site & half remote;
• Permanent position as of the hiring, full-time 37.5hrs per week.

Why Charles River ?

• We offer competitive benefits and advantages from day one to support your well-being;
• Paid development training;
• Employee and family assistance program;
• Excellent welcome program for new employees as well as in-house advancement and career development opportunities;
• Access to a doctor and various health professionals (telemedicine);
• 4 weeks' Vacation & 10 Personal day policy;
• Many social activities!

If you are interested in contributing to the well-being of our communities, not only across the country but around the world, please join us. This is Your Moment.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.