Regeneron Pharmaceuticals, Inc

Principal Toxicologist

Regeneron Pharmaceuticals, Inc • $150K — $245K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Advanced Degree (PhD, DVM) in Toxicology or related field, or Master's with significant experience
  • 5+ years in pharmaceutical industry (PhD) or 15+ years (Master's)
  • Expertise in nonclinical safety assessment study design and reporting
  • Experience as a nonclinical safety representative on drug development teams
  • Strong knowledge of global regulatory guidelines and safety strategies

Responsibilities

  • Represent toxicology on global research and development teams, articulating safety strategies
  • Develop regulatory risk assessment strategies for toxicology study execution
  • Collaborate with experts to design nonclinical safety programs
  • Oversee CRO activities, including study design and data interpretation
  • Communicate safety data and risk assessments to stakeholders and regulatory agencies
  • Author and review safety content for global regulatory submissions
  • Mentor junior scientists and drive continuous improvement initiatives

Benefits

  • Work in a collaborative, on-site environment in Tarrytown, NY
  • Opportunity to engage in diverse therapeutic modalities
  • Chance to influence drug safety from preclinical to clinical stages
  • Involvement in policy development for toxicology research
  • Access to continuing education and professional development opportunities
Full Job Description
Principal Toxicologist to join our Toxicology group within Drug Safety and Pharmacometrics, applying scientific and regulatory expertise to lead nonclinical development programs with minimal supervision. You'll have a deep understanding of global regulatory guidelines to ensure all aspects of nonclinical safety are met, enabling progression of assigned programs across the life cycle of a therapeutic asset. You'll manage all aspects of multiple programs across therapeutic classes, demonstrating the ability to prioritize and meet deadlines with high-quality deliverables, and will work in collaboration with other members of the toxicology group to develop policies and procedures related to the conduct of toxicology research at Regeneron. Candidates with experience across diverse therapeutic modalities, such as monoclonal antibodies, oligonucleotides, and gene therapies, are preferred. Prior experience providing toxicology and nonclinical safety support for Ophthalmology, Oncology, and/or Infectious Diseases programs is a plus.

When & where:

  • Location: On-site in Tarrytown, NY

Discover your role:

  • Represents toxicology on global research and development project teams, communicating non-clinical safety strategy
  • Develops regulatory risk assessment strategies and contributes to program planning, budgeting, and the execution of toxicology studies to support regulatory and clinical development milestones
  • Collaborates with cross-functional subject matter experts to design and execute nonclinical safety programs that support drug development and clinical advancement
  • Provides scientific oversight of CRO activities, including study design, conduct, monitoring, data interpretation, and reporting
  • Communicates nonclinical safety data, risk assessments, and development strategies to internal and external stakeholders, including regulatory agencies
  • Authors and reviews nonclinical safety content for global regulatory submissions and provides toxicology expertise in interactions with health authorities
  • Collaborates with external partners and consultants to advance nonclinical safety strategies and support drug development programs
  • Maintains currency with GLP regulations and ICH, FDA, and EMEA non-clinical safety guidelines
  • Keeps up with the latest scientific developments by reading current literature and attending conferences
  • Drives continuous improvement initiatives and mentors junior scientists to promote scientific excellence and professional development

This role requires:

  • Advanced Degree (e.g., PhD, DVM) in Toxicology or a closely related discipline, plus 5+ years, or a Master's Degree plus 15+ years, of relevant pharmaceutical industry experience
  • Demonstrated expertise in the design, oversight, interpretation, and reporting of nonclinical safety assessment studies supporting drug development
  • Proven experience serving as the nonclinical safety representative on cross-functional drug development teams and contributing to regulatory submissions (e.g., INDs, CTAs, BLAs/MAAs)
  • Strong knowledge of global regulatory requirements and nonclinical safety strategies across all stages of pharmaceutical development


Salary Range (annually)
$150,500.00 - $245,500.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

Explore Job Opportunities and Growth

Regeneron offers a variety of job opportunities that encourage professional growth and personal achievement. Whether you're seeking an entry-level position or a more senior role, you will find a path that aligns with your career ambitions and skills. Our supportive culture emphasizes leadership development and diversity training, ensuring every team member can thrive.

Internship Programs

Kickstart your career with a Regeneron internship. Our programs provide invaluable industry experience, mentoring from seasoned professionals, and opportunities to develop skills that are crucial in the biotech field. Interns at Regeneron gain hands-on experience, contributing to projects that matter.

Benefits and Culture

Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

Networking and Professional Development

Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

Join Our Team

Discover the impact you can make in a career at Regeneron Pharmaceuticals, Inc. Search for open positions that match your skills and interests. We are continuously hiring and looking for passionate, curious, and innovative team players.

Stay Connected

Keep up to date with the latest at Regeneron by following our careers blog. Gain insights from the experts and learn more about the exciting world of biotech at Regeneron Pharmaceuticals, Inc.

Prepare for Your Interview

Ready to join us? Prepare your resume and refine your interview skills to become part of a company that’s dedicated to changing lives. Personalize your job search and get tailored job alerts directly to your inbox, so you never miss an opportunity to be part of our team. At Regeneron Pharmaceuticals, Inc, your career is poised for tremendous growth and innovation. Explore the opportunities today and be part of a team that’s shaping the future of biotechnology.
Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ

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