McKesson

Principal Solution Architect, Enterprise Integration

McKesson$170K — $284K *
Enterprise Technology
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree or equivalent; typically requires 13+ years of experience, with at least 8 years directly related to the field.
  • Master's or Doctorate qualifications may reduce years of experience required.
  • Expertise in enterprise architecture principles (TOGAF® 10, ADM, governance).
  • Advanced visualization skills (C4 model) for clear communication with executives.
  • Fluency in Well-Architected practices across security, reliability, performance, and operations.
  • Multi-cloud certifications (AWS, Azure, GCP) to guide modernization.
  • Strong data integration and zero-trust knowledge for large-scale enterprise needs.

Responsibilities

  • Set and govern the enterprise architecture strategy and roadmap.
  • Champion transformation initiatives with executive leaders.
  • Direct enterprise-wide business capability modeling and technology roadmaps.
  • Establish design standards and critically assess major platform solutions.
  • Lead the execution of architectural changes across various portfolios.
  • Create and evolve governance principles and quality programs.
  • Drive innovation by evaluating and adopting emerging technologies.

Benefits

  • Comprehensive Total Rewards package, including competitive compensation.
  • Leadership opportunities to influence technology direction at a large scale.
  • Exposure to cutting-edge projects in an established company.
  • Participation in external forums to shape industry standards.
  • Professional development through mentoring and coaching programs.
Full Job Description

Position Summary

 

The Principal Solution/IT Architect defines and governs the enterprise‑wide solution architecture vision, strategy, and standards that unlock innovation and measurable business value. The role partners with executive leadership to integrate architecture with strategic initiatives, directs cross‑enterprise fit‑gap analysis, and sets migration frameworks that evolve the landscape across business units and platforms. It anticipates disruptive technologies, shapes organizational response, and ensures seamless integration for agility, resilience, and compliance.

Operating with full autonomy, the Principal Architect leads the development and continuous improvement of reference implementations and patterns, establishes enterprise design principles and governance, and represents McKesson’s architectural strategy in external forums. The role translates enterprise needs into actionable roadmaps, resolves unique and precedent‑setting challenges, and communicates complex decisions clearly to non‑technical audiences and external stakeholders—building a high‑performing architecture community that sustains competitive advantage.

 

Key Responsibilities:  

Set enterprise architecture strategy and roadmap. Define long‑term vision, principles, and governance; champion transformation and innovation at the executive level. 

Own capability alignment. Direct enterprise business‑capability modeling and technology roadmaps; ensure investments deliver measurable value and risk reduction. 

Define design standards and approve critical solutions. Establish option‑evaluation standards; approve design specifications for major platforms; lead enterprise reviews. 

Direct implementation at scale. Govern execution and modifications across portfolios; set protocols for rapid resolution of systemic issues. 

Lead governance end‑to‑end. Establish and evolve principles, technology standards, and quality programs; resolve enterprise‑level exceptions; ensure regulatory alignment. 

Institutionalize well‑architected practices. Define organization‑wide KPIs/OKRs for security, reliability, performance, cost, and operations; drive adjustments to optimize outcomes. 

Drive enterprise innovation. Lead evaluation and adoption of emerging technologies; prioritize transformations that advance competitive advantage. 

Influence and coach at scale. Run enterprise mentoring programs for architects; champion DevOps, cloud, and AI; act as architecture change leader. 

Represent McKesson externally. Shape industry practices and standards through partnerships, forums, and thought leadership. 

Guide strategic M&A. Set evaluation frameworks; lead due diligence, integration vision, and senior stakeholder alignment for technology investments. 

 Minimum Requirements

  • Degree or equivalent and typically requires 13+ years, with 8+ years, of direct workrelated experience. Less years required if has relevant Master's or Doctorate qualifications

 

Critical Skills

  • Enterprise architecture mastery (TOGAF® 10 concepts, ADM, governance) to set organization‑wide principles, decision frameworks, and target‑state roadmaps. 
  • Advanced architecture visualization using the C4 model (context, container, component) for clear, executive‑ready storytelling and alignment. 
  • Well‑Architected fluency across security, reliability, performance efficiency, cost optimization, and operations; ability to embed KPIs/OKRs in enterprise designs. 
  • IT service management alignment (ITIL® 4 SVS/practices) to ensure operational soundness, supportability, and compliance at scale. 
  • Secure‑by‑design leadership with demonstrable application of OWASP Top 10 mitigations across platforms and integrations. 
  • Multi‑cloud and platform depth (e.g., AWS Solutions Architect – Professional, Azure Solutions Architect Expert, GCP Professional Cloud Architect) to steer modernization and multi‑account strategies. 
  • Data, integration, and zero‑trust expertise (APIs, eventing, data platforms, identity) to meet enterprise scale, latency, resilience, and regulatory needs. 
  • Executive influence and narrative clarity—framing strategic options, risks, and trade‑offs with implementable, board‑ready guidance. 
  • Operability at scale—governance for CI/CD, IaC, observability, backup/DR, HA patterns, and cloud landing‑zone standards across portfolios. 
  • Competency proficiency for L6 (Principal Architect): Adaptability (Leading), Architecture & Master Planning (Expert), Collaboration & Partnership (Expert), Communication & Internal Marketing (Leading), Design Thinking (Expert), Digital Acumen (Expert), Problem Solving (Expert), Strategic Decision Making (Leading), Business Function Knowledge (Expert), Customer & Business Driven (Leading), Leadership (Leading). 

 

Additional Qualifications

 

  • Proven ownership of enterprise standards and governance, including exception management and organization‑wide quality assurance.
  • Demonstrated leadership of mission‑critical transformations—from capability strategy and roadmap through execution and optimization—in regulated or complex environments.
  • Experience representing architecture in executive and external forums, influencing technology direction, partnerships, and industry practices.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$170,900 - $284,900

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

About McKesson

McKesson Corporation provides medicines, pharmaceutical supplies, information and care management products and services across the healthcare industry. The Company operates in two segments. The McKesson Distribution Solutions segment delivers ethical drugs, medical-surgical supplies and equipment and health and beauty care products throughout North America. This segment also provides specialty pharmaceutical solutions for biotech and pharmaceutical manufacturers, sells financial, operational and clinical solutions for pharmacies (retail, hospital, long-term care) and provides consulting, outsourcing and other services. The McKesson Technology Solutions segment delivers enterprise-wide clinical, patient care, financial, supply chain, strategic management and software solutions. In July 2011, the Company acquired Portico Systems from Safeguard Scientifics, Inc. On March 25, 2012, it acquired the independent banner and franchise businesses of Katz Group Canada Inc. McKesson Distribution Solutions delivers pharmaceuticals to retail pharmacies and institutional providers like hospitals and health systems. They operate pharmaceutical distribution centers across the country, serving customers in all 50 states. They also deliver a comprehensive offering of health care products, technology, equipment and related services to the alternate site market, including physician offices, surgery centers, long-term care facilities and home care businesses across the country. McKesson is currently the largest pharmaceutical distributor in North America. McKesson also operates McKesson Canada and has an equity holding in Nadro, a leading distributor in Mexico.

McKesson Careers

Join McKesson, a leading global healthcare company, and be part of a team that is redefining the future of healthcare. With a variety of job opportunities available, McKesson is the perfect place to advance your career, whether you're a seasoned professional or just starting out. Work You’ll Do At McKesson, we are committed to improving care in every setting—one product, one partner, one patient at a time. We’re seeking talented professionals to join our team and contribute to a culture of innovation, diversity, and leadership. Our employees are driven by a deep sense of purpose and a desire for continuous growth and improvement. Empower Your Future in Healthcare With positions ranging from internships to leadership roles, McKesson offers unparalleled employment opportunities to develop your skills and advance your career. Our commitment to diversity training ensures that all team members have the opportunity to thrive. Join a team where your skills will be honed, your professional growth will be supported, and where you can genuinely see the difference you make in the lives of patients around the world. Innovative Work Environment McKesson is at the forefront of healthcare innovation. Our team is constantly exploring new ways to improve patient outcomes and streamline care processes. This commitment to innovation is what sets us apart and what makes McKesson an exciting place to work. Career Development and Benefits McKesson believes in nurturing the potential of its employees through robust career development programs and comprehensive benefits designed to support your life and well-being. From leadership training to health and wellness benefits, we ensure our team members are equipped to meet their professional and personal goals. Explore Job Opportunities Whether you’re looking for an internship to kickstart your career, or a senior position to utilize your extensive experience, McKesson offers a range of opportunities. Explore our open positions and find where you can make a difference at McKesson. Stay Connected Join Our Team Search for open positions that match your skills and interests. We are looking for passionate, curious, and solution-driven team players who are ready to take the next step in their careers. Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Networking and Professional Growth At McKesson, networking and professional growth are part of our everyday environment. We encourage our employees to connect, share, and learn from each other to foster personal and professional development. Job Alert Emails Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await you at McKesson. Join McKesson today and be part of a team that is dedicated to shaping the future of healthcare.
Learn more about McKesson
Size
58,000 employees
Market Cap
$53.7 billion
Industry
Net Income
-$4.1 billion
Founded
1833
5 Year Trend
+5.9%
Revenue
$237.6 billion
NASDAQ

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