Johnson & Johnson

Principal Scientist, Toxicology

Johnson & Johnson • $130K — $155K *
Springs, PA 15562Hybrid
Pharmaceuticals & Biotech
5 - 7 years of experience
Today
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Job Overview by Ladders

Qualifications

  • Master's degree in biomedical sciences, toxicology, pharmacology, or similar education; PhD preferred.
  • Minimum 5 years of relevant experience in toxicology.
  • Experience as a Study Director or Study Monitor overseeing in vivo toxicology studies.
  • Knowledge of major species used in toxicology models is essential.
  • Strong communication skills with experience in scientific data evaluation and integrated safety assessment.

Responsibilities

  • Design in vivo general toxicology studies for various modalities.
  • Interpret data and review reports for toxicology and safety pharmacology studies.
  • Oversee contracted in vivo and in vitro safety pharmacology studies in compliance with GLP.
  • Collaborate with multi-disciplinary teams providing expertise on drug development.
  • Engage in scientific discussions to inform critical development decisions.
  • Provide input on mechanisms of toxicity and propose follow-up studies.
  • Foster collaborations with internal and external partners to meet pipeline priorities.

Benefits

  • Hybrid work model offering flexibility.
  • Active participation in internal and external committees.
  • Opportunities for professional development and growth.
  • Engagement with innovative toxicological research approaches.
  • Collaboration with global teams in the US, Belgium, and China.
Full Job Description
Job Function:
Discovery & Pre-Clinical/Clinical Development

Job Sub Function:
Nonclinical Safety

Job Category:
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description:

We are searching for the best talent for a Principal Scientist, Toxicology in Spring House, PA.

Purpose: This Principal Scientist in Nonclinical Safety and Submissions, a department in the Preclinical Sciences and Translational Safety (PSTS) organization within Johnson & Johnson Innovative Medicine, supports nonclinical safety evaluation in late discovery and development for various therapeutic areas.

You will be responsible for:
  • Design of in vivo general toxicology studies for biologics, small molecules, and other modalities.
  • Integrated scientific data interpretation and critical report review for general toxicology and safety pharmacology studies.
  • Oversee and monitor contracted in vivo toxicology and in vitro/in vivo safety pharmacology studies in compliance with Good Laboratory Practices (GLPs) and animal welfare regulations, following company policies and standard operating procedures.
  • Engagement in multi-disciplinary teams within PSTS and close collaboration with nonclinical project representatives to provide scientific and technical expertise on drug development programs.
  • Participate in issue-resolution teams through active engagement in scientific discussions and the shaping of strategies designed to support and inform critical development decisions.
  • Provide strong scientific input regarding potential mechanisms of toxicity in molecular pathways and propose appropriate follow-up. Maintain up-to-date knowledge regarding innovative approaches in toxicological research.
  • Work independently, foster constructive cross-functional collaborations with both internal and external partners, and be able to prioritize workload in alignment with pipeline priorities.
  • Adhere to timelines; proactively identify and communicate study-related issues and develop contingency plans.
  • The candidate will contribute to the success and growth of PSTS through active participation in internal and external committees / working groups and will closely interact with scientists in other functional areas including pathology, bioanalysis, toxicokinetics, and development project leaders in the US, Belgium, and China.


Qualifications / Requirements:

Education:
  • Minimum of Master's Degree in biomedical sciences, toxicology, pharmacology, or similar education is required; PhD is preferred.


Experience/Skills:
  • A minimum of 5 years of relevant experience is required.
  • Experience as a Study Director or Study Monitor conducting/overseeing in vivo toxicology studies supporting projects in discovery through development is required
  • Knowledge of major species typically evaluated as toxicology models is required
  • Knowledge in immunology or immunotoxicology is preferred.
  • Strong written and verbal communication skills and the ability to negotiate and influence decision-making processes, think and manage issues to resolution, and contribute to study teams and scientific discussions are required with prior experience in scientific data evaluation, integrated safety assessment, and scientific writing
  • Capable of making fast decisions when necessary, while maintaining positive and inclusive team relationships, is required
  • Personal leadership skills, a pro-active and flexible attitude, sense of urgency and excellent collaboration skills are required
  • Strong critical thinking skills and a strong scientific knowledge in toxicology, safety pharmacology, pathology, and drug metabolism/pharmacokinetics, and an ability to apply this knowledge to influence development programs are preferred


#LI-Hybrid

Required Skills:

Preferred Skills:

About Johnson & Johnson

Scio Diamond creates single-crystal Type IIa diamonds for the jewelry market and for industrial applications. It employs a patent-protected chemical vapor deposition (CVD) process in a precisely controlled laboratory setting to produce diamonds. It was founded in 2009 and is headquartered in Greenville, South Carolina.

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Learn more about Johnson & Johnson
Size
141,700 employees
Market Cap
$462.7 billion
Industry
Pharmaceuticals & Biotech
Net Income
$14.7 billion
Founded
1886
5 Year Trend
+5.5%
Revenue
$82.5 billion
NASDAQ
JNJ
* Ladders Estimates

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