AbbVie

Principal Research Scientist II

AbbVie • $120K — $150K *
Worcester, MA 01604In-Person
Pharmaceuticals & Biotech
8 - 10 years of experience
Today
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Job Overview by Ladders

Qualifications

  • Advanced degree in Biology, Biochemistry, Chemical Engineering, or Data Science with extensive experience in related roles.
  • Strong problem-solving skills with a proven ability to optimize complex processes.
  • High level of organization and attention to detail, able to manage multiple priorities.
  • Deep knowledge of cell culture processes including development and scaling of recombinant proteins.
  • Exceptional communication skills and executive presence in a scientific environment.

Responsibilities

  • Manage a team of scientists and engineers focused on bioprocess improvement.
  • Lead development for cell culture processes supporting monoclonal antibodies and other therapies.
  • Conduct process characterization activities for cell culture.
  • Collaborate with cross-functional teams to review regulatory submission sections.
  • Mentor team members to build a high-performance culture.
  • Build relationships across functions to enhance product quality and efficiency.
  • Advance cell culture expertise by monitoring industry trends and sharing knowledge.

Benefits

  • Comprehensive benefits package including paid time off and medical/dental/vision insurance.
  • Eligibility for long-term incentive programs such as stock options or bonuses.
  • Opportunities for professional development and mentorship.
Full Job Description
Job Description

The Cell Culture Development organization within Operations leads process development and tech transfer for cell culture processes supporting clinical manufacturing and commercialization of therapeutic proteins across AbbVie's pipeline. The team also provides subject matter expertise and experimental support for the manufacture of commercial biologics.

The role is responsible for managing a team of scientists and engineers to solve complex challenges across AbbVie's diverse biologics pipeline. The successful candidate will collaborate with cell culture scientists to develop and implement strategies for pre-clinical, early-stage, and late-stage cell culture development, and will lead cell culture media development efforts.

Key Responsibilities:
  • Manage a group of 2+ scientists and engineers (BS/MS and PhDs) focused on systems biology applied to bioprocess improvement, including cell culture media development and process optimization.
  • Lead cell culture process development for monoclonal antibodies, bi-specifics, ADCs, fusion proteins and other molecular formats for early- and late-stage clinical assets.
  • Lead PPQ enabling cell culture process characterization activities.
  • Participate in cross-functional CMC teams and review relevant sections of regulatory submissions (e.g. IND, BLA, MAA, etc...).
  • Mentor and develop staff to foster a high-performance culture that achieves business and scientific objectives.
  • Build strong relationships with other process and analytical development, Manufacturing Sciences and Technology, R&D, Manufacturing, Quality and Regulatory teams to improve efficiency, productivity, robustness and product quality.
  • Advance technical expertise within the cell culture development field by tracking emerging trends and technologies within the field through internal and external sources, and proactively sharing knowledge with the team, peers and management.
  • Represent the organization as a scientific thought leader through conference presentations, publications, and broader engagement in the external and internal scientific community.


Qualifications
  • Advanced degree in Biology, Biochemistry, Chemical Engineering, Data Science, or a related discipline, with 16+ years of experience for BS holders, 14+ years for MS holders, or 8+ years for PhD holders; highly qualified candidates with fewer years of experience may also be considered.
  • Demonstrated executive presence with exceptional interpersonal and communication skills, strong scientific curiosity, and a proven ability to solve complex problems and drive optimization.
  • Self-directed and highly organized, with strong attention to detail, outstanding planning and troubleshooting capabilities, and the ability to manage multiple priorities effectively.
  • Deep understanding of cell culture processes, including cell and molecular biology, process development, scale-up and scale-down, recombinant protein production, and protein characterization.


Preferred Qualifications:
  • Demonstrated proficiency in bench scale bioreactor and other high-throughput cell culture systems for the optimization of cell culture processes.
  • Experience with or ability to lead a team with focus on cell culture media development, including the application of complex statistics and systems biology.


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

Explore Job Opportunities

AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

Networking and Career Advancement

At AbbVie, networking doesn’t just enhance your career; it propels it. We encourage our employees to engage internally and externally to build relationships that foster personal and professional growth.

Join Our Team

Search open positions that match your skills and interests. We are looking for passionate, curious, and innovative team players who are ready to make a difference.

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Explore AbbVie Jobs

Whether you’re seeking to advance your career in a dynamic and empowering environment, or looking for a place where you can innovate, lead, and contribute to something bigger, AbbVie is the place for you. Join us in our mission to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow.
Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Pharmaceuticals & Biotech
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ
ABBV
* Ladders Estimates

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