Member of Technical Staff, Computational Biology

Radical Numerics, Inc

$120K — $150K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in genetics, computational biology, or similar field, or 3+ years in biotech with proven impact.
  • Experience curating and analyzing large biological datasets.
  • Proficiency in Python and data-related tools for reproducible workflows.
  • Ability to analyze model outputs and provide actionable insights.
  • Strong communication skills to connect scientific and engineering teams.
  • Demonstrated curiosity and resilience in solving scientific challenges.

Responsibilities

  • Source and normalize large-scale biological datasets with rigorous metadata.
  • Develop evaluation suites that test generative biological models.
  • Collaborate with AI engineers to analyze model outputs and suggest improvements.
  • Integrate external datasets while ensuring compliance and ethical standards.
  • Communicate findings and best practices within the organization.

Benefits

  • Contribute to advanced biological models for global health solutions.
  • Work in a collaborative culture that values creativity and rigor.
  • Receive competitive compensation and comprehensive benefits.
  • Support for ongoing learning and professional development.
Full Job Description
About the Role

As a science-focused Member of Technical Staff, you will curate the multimodal biological datasets that power our models, analyze model behavior, and ensure our model outputs meet rigorous scientific standards. You'll co-develop benchmarks, filters, and validation pipelines with engineering peers so biological world models remain trustworthy and actionable.

What You'll Do
  • Source, normalize, and steward large-scale genomic, epigenomic, transcriptomic, proteomic, and imaging datasets with rigorous metadata and provenance.
  • Build evaluation suites and benchmarks that stress-test generative biological models across modalities and tasks.
  • Partner with AI engineers to analyze model outputs, run ablations, and surface insights that guide future architecture and training improvements.
  • Integrate new datasets and annotations from external collaborators while maintaining compliance, privacy, and ethical standards.
  • Communicate findings and best practices across Radical Numerics so teams can trust and act on model results.
What We're Looking For
  • PhD in genetics, computational biology, or a related field, OR demonstrated experience in biotech with a strong track record of impact over 3+ years.
  • Proven experience curating, harmonizing, and analyzing large biological datasets (e.g., genomics, single-cell, spatial, or imaging).
  • Fluency with Python, data tooling, and reproducible workflows (git, notebooks, containers).
  • Ability to interrogate model outputs, debug unexpected behaviors, and translate findings into actionable recommendations.
  • Clear communicator who can bridge scientific context with engineering teams and partner organizations.
  • Curiosity and resilience when tackling open-ended scientific challenges.
Nice to Have
  • Familiarity with generative model evaluation, red-teaming, or safety analysis in scientific domains.
  • Experience with statistical validation, quality control, or benchmarking for scientific or ML systems.
  • Experience building benchmarking frameworks or open datasets that became community standards.
  • Contributions to shared analytics tooling or reproducible research pipelines.


Why Radical Numerics
  • Help produce the multimodal biological world models that will power rapid detection, response, and countermeasures across global health.
  • Collaborative culture that values rigor, creativity, and cross-disciplinary partnership across AI labs, biotechs, hospital systems, and national research institutes.
  • Competitive compensation, comprehensive benefits, and support for continual learning.

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