Job Summary:The Scientist will serve as a technical leader and subject matter expert responsible for high-complexity analytical testing in support of an FDA proposal. The role requires extensive hands-on experience operating, maintaining, and troubleshooting advanced chromatography and mass spectrometry instrumentation, including GC-MS platform.
Essential Responsibilities:- Preparation of test samples for analysis including forced degradation and stability testing
- Independently operate, maintain, and troubleshoot analytical systems.
- Perform routine and advanced instrument maintenance, including column replacement, and performance verification.
- Diagnose complex instrument and method performance issues and implement corrective actions to minimize downtime.
- Serve as a technical resource for instrument performance, repairs, vendor interactions, and troubleshooting support.
- Maintain accurate and complete technical records.
- Evaluate and trend QA/QC metrics, including internal standards, surrogates, blanks, laboratory control samples, matrix spikes/matrix spike duplicates, and calibration criteria (where applicable).
- Assist in developing technical documentation, validation summaries, method performance studies, and related reports.
Education & Experience:- PhD/MSc, Chemistry; 5+ years of experience
- GC-MS technology specializing in NTA (Non-targeted Analysis) for the identification of unknowns
- Estimated 498 NTA analysis
- 228 Forced Degradation replicates over 2 months (38 Sample Types X 3 Replicates X 2 Conditions/Timepoint variants)
- 270 Stability Study replicates (over 12 months)
Required Technical Qualifications- Advanced technical understanding of GC-MS and/or LC-qTOF theory, operation, maintenance, and troubleshooting.
- Strong understanding of advanced chromatography techniques, including GC-MS and/or LC-qTOF.
- Experience with Agilent systems.
- Experience in advanced chromatography techniques, method development, routine testing, problem solving, and unknown determination.
- Ability to read and interpret chromatograms, mass spectra, analytical reports, and method performance data.
- Manual dexterity required for instrument maintenance and sample preparation.
Communication and Work Style Expectations- Excellent communication skills in English, both oral and written, for technical documentation, reporting of experimental results, and oral presentations.
- Ability to present technical concepts and simulated or experimental results clearly to technical and non-technical audiences.
- Well organized and able to work independently to complete projects, while also contributing effectively as part of a team.
- Demonstrated ability to support high-complexity analytical testing through sound judgment, attention to detail, and proactive problem solving.
The compensation details provided below reflect the expected pay range for this role, based on the selected compensation structure and applicable guidelines. Actual pay within this range may vary depending on factors such as experience, skills, qualifications, and geographic location. Additional components of total rewards-such as bonuses, benefits, or incentives-may also apply where applicable.
Salary Range for Pay Transparency
$85,000-$110,000 CAD
