Roche

Machine Learning Scientist, Structure-Function ML, AI for Drug Discovery (AIDD)

Roche$141K — $262K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • M.S. or PhD in Computer Science, Statistics, Physics, or a related field.
  • 1+ years of hands-on experience with machine learning model design and training.
  • Published works related to de novo antibody design in reputable journals.
  • Proficient in Python and at least one deep learning framework (PyTorch, TensorFlow, or JAX).
  • Experience with MLOps frameworks (Hydra, Weights & Biases).
  • Public codebase of computational de novo antibody design.
  • Familiar with antibody sequence and structure data.

Responsibilities

  • Develop machine learning methods focused on modeling biological data.
  • Deliver deep learning software solutions for drug discovery.
  • Collaborate with AI/ML scientists and global research teams.
  • Write structured and maintainable code, participating in code reviews.
  • Contribute to an innovative and collaborative team culture.
  • Partner with biologists and technologists for new protein design methods.

Benefits

  • Eligible for a discretionary annual bonus based on performance.
  • Access to various detailed benefits as outlined in provided documentation.
Full Job Description

The Opportunity

The Structure-Function ML group in Basel within , a division devoted to developing machine learning-based methods for de novo antibody design, seeks exceptional researchers who have a demonstrated research background in machine learning and protein structural biology and design, a passion for independent research and technical problem-solving, and a proven ability to develop and implement ideas from research into production. We are looking for a very talented Machine Learning Scientist to join Prescient Design/AI4DD. The successful candidate will contribute to our antibody design efforts, partner with biologists, technologists and drug discoverers to develop new machine learning methods for de novo protein design with special application to protein therapeutics.

In this role, you will:

  • Develop cutting-edge machine learning methods for modeling biological data, focusing on structural biology.

  • Deliver deep learning-based software solutions that accelerate drug discovery and therapeutic development in support of our de novo antibody design and efforts.

  • Collaborate with AI/ML scientists and form close working relationships with global research teams.

  • Write structured, tested, and maintainable code while participating in proactive code reviews.

  • Actively shape and contribute to our collaborative and innovative team culture.

  • Partner with biologists and technologists to develop new methods for de novo protein design.

Who you are

  • You hold an M.S. or PhD in Computer Science, Statistics, Physics, or a related technical field and possess 1+ years of hands-on experience designing and training machine learning models on large datasets.

  • You have published on denovo antibody design in relevant journals like Nature Biotechnology, Neurips, or ICML.

  • You are proficient in Python and at least one deep learning framework like PyTorch, TensorFlow, or JAX.

  • You have experience with using MLOps frameworks like Hydra and Weights & Biases.

  • You have a public codebase of computational denovo antibody design (available on e.g. GitHub)

  • You have demonstrated experience with modern techniques, including hallucination or folding models.

  • You bring prior experience or familiarity working with antibody sequence and structure data, which is a plus.

  • You are an excellent communicator, fluent in English, with a passion for driving projects in cross-functional environments.

Relocation benefits are NOT available for this job posting

The expected salary range for this position based on the primary location of New York is $141,100 - 262,100 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

#ComputationCoE

#tech4lifeComputationalScience

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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