Alkermes

IT Principal, SAP Architect

Alkermes$175K — $197K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in computer science or related field; advanced degree preferred.
  • 8-12 years of technology experience, ideally in Life Sciences or regulated environments.
  • Extensive S/4HANA architecture experience with ownership of solution design governance.
  • Proven track record on an end-to-end S/4HANA implementation close to go-live.
  • Strong grasp of core SAP processes and cross-functional integration.
  • Hands-on experience with SAP BTP and Integration Suite/CPI in complex settings.
  • Strong stakeholder management and communication skills.

Responsibilities

  • Own the end-to-end S/4HANA solution architecture, ensuring business process alignment.
  • Lead design authority forums, driving decisions and resolving technical gaps.
  • Validate solution readiness pre-go-live, focusing on performance and operational handover.
  • Collaborate with leadership and delivery teams on cutover and integration strategies.
  • Engage stakeholders, providing architectural leadership during delivery phases.
  • Ensure adherence to SAP Clean Core principles protecting the architecture.
  • Define BTP extensions and integration approaches for secure, scalable designs.
  • Oversee integration quality and readiness for production environments.

Benefits

  • Competitive benefits package with performance-based bonuses.
  • Opportunities for professional development and SAP certifications.
  • Engaging work within a collaborative and innovative team environment.
Full Job Description
Job Description

We are seeking a Prnicpal SAP S/4HANA Solution Architect to provide end-to-end architecture leadership and long-term ownership of the S/4HANA solution landscape. While the programme is approaching go-live in July, the primary focus of this role is to define and govern the target architecture, ensure architectural integrity across all workstreams, and shape the roadmap for ongoing evolution, optimisation, and innovation.

The Solution Architect will provide governance and design assurance across the SAP landscape (process, data, integration, security, and operations), supporting delivery through go-live and establishing a sustainable foundation for steady-state operations. This includes adherence to SAP Clean Core principles and enterprise standards, clear design decision-making, and a forward-looking architecture roadmap, with SAP BTP and SAP Integration Suite/CPI as key enabling components for integration and extensibility.

Responsibilities

  • Own and govern the end-to-end solution architecture for the S/4HANA programme, ensuring alignment across business processes, data, applications, integration, and security.
  • Lead architecture governance and design authority forums; drive decisions, manage exceptions, and resolve cross-stream design gaps, risks, and technical debt.
  • Validate end-to-end solution readiness ahead of go-live, including non-functional requirements (performance, resilience, monitoring, supportability) and operational handover into hypercare.
  • Partner with programme leadership, functional leads, and delivery teams to support cutover planning, environment strategy, data migration validation, and integration sequencing.
  • Engage senior stakeholders and provide architectural leadership across delivery phases; act as escalation point for complex, cross-functional technical issues.
  • Ensure adherence to SAP Clean Core principles and the agreed extensibility strategy; protect the core while enabling continuous improvement.
  • Define and govern BTP-based extensions and integration approaches (SAP Integration Suite/CPI, APIs, event-driven patterns), ensuring secure, scalable, and supportable designs.
  • Oversee integration readiness (build quality, testing, monitoring/alerting, runbooks), ensuring all interfaces are production-ready and operable.
  • Support rapid issue resolution during go-live and early life support, including integration failures, performance issues, and data inconsistencies, coordinating across SAP and non-SAP platforms.
  • Define and transition to a sustainable target architecture and support model, including principles, standards, and a roadmap for post go-live optimisation and innovation.


Qualifications

  • Bachelor's degree in computer science, information management, mathematics, statistics, biostatistics, business, or related field; advanced degree preferred
  • 8-12 years of technology experience, preferably in Life Sciences or within a regulated environment
  • Extensive experience as an SAP Solution Architect on S/4HANA programmes, owning end-to-end solution architecture and design governance.
  • Proven experience in at least one end-to-end S/4HANA implementation approaching or at go-live, including hypercare/early life support.
  • Strong understanding of core SAP processes and cross-functional integration (e.g., FI/CO, MM, SD, PP) and how they operate end to end.
  • Solid understanding of integration patterns (APIs, messaging, event-driven), identity and access, and cloud/security considerations across SAP and non-SAP platforms.
  • Hands-on experience with SAP BTP and SAP Integration Suite/CPI (design, monitoring, troubleshooting) in complex integration landscapes.
  • Experience defining non-functional requirements and operational readiness (monitoring/alerting, logging, runbooks, support model) for production environments.
  • Strong understanding of cutover planning, data migration validation, environment management, and release strategy.
  • Experience working with SAP Activate (or comparable delivery methodology) and collaborating effectively across SI and internal teams.
  • Strong stakeholder management, communication, and decision-making skills; able to balance speed of delivery with architectural integrity in time-critical environments.

Desired Skills
  • SAP certifications in S/4HANA, BTP, or Integration.
  • Experience with RISE with SAP or S/4HANA Cloud.
  • Knowledge of enterprise architecture frameworks (e.g., TOGAF).


Soft Skills
  • Excellent communication and stakeholder management skills.
  • Strong analytical and problem-solving abilities.
  • Proven leadership in complex, multi-stream delivery environments.
  • Delivery-focused with strong attention to detail


The annual base salary for this position ranges from $175,000 to $197,000. In addition, this position is eligible for an annual performance pay bonus. Exact compensation may vary based on skills, training, knowledge, and experience. Alkermes offers a competitive benefits package. Additional details can be found on our careers website: www.alkermes.com/careers#working-here

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About Alkermes

Alkermes plc is a fully integrated, global biopharmaceutical company developing innovative medicines in the fields of neuroscience and oncology. The company has a portfolio of proprietary commercial products focused on addiction and schizophrenia, and a pipeline of product candidates in development for schizophrenia, bipolar I disorder, neurodegenerative disorders, and cancer. Headquartered in Dublin, Ireland, Alkermes plc has an R&D center in Waltham, Massachusetts; a research and manufacturing facility in Athlone, Ireland; and a manufacturing facility in Wilmington, Ohio. Alkermes was founded in 1987 and has approximately 2,000 employees.
Learn more about Alkermes
Size
2,211 employees
Market Cap
$4.1 billion
Industry
Net Income
-$110.8 million
Founded
2011
5 Year Trend
+9.5%
Revenue
$1 billion
NASDAQ

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