Work Schedule

Environmental Conditions

Job Description

• Deliver responsive, on-site oligonucleotide LC–MS bioanalytical support, scaled to the weekly study schedule.
  
• Maximize uptime and analytical readiness of in-scope LC–MS and supporting laboratory instruments.
  
• Resolve routine and minor instrument issues at the point of need, bridging coverage until vendor service attends site and reserving vendor engagements for repairs that exceed user-level scope.
  
• Maintain instrument software, computer systems, operating-system updates, licensing, and version control.
  
• Provide secondary small-molecule DMPK bioanalytical capacity when oligonucleotide and instrument demands allow.
  
• Deliver a visible, collaborative presence that integrates with the customer’s scientific and laboratory support teams.
  

• Assay execution: Development and execution of oligonucleotide LC–MS bioanalytical workflows, including sample preparation, extraction, LC–MS analysis, and data review.
  
• Method support: Support of method transfer, familiarization, and routine troubleshooting for oligonucleotide assays, including chromatographic and ion-pairing performance issues.
  
• Workflow flexibility: Ability to ramp quickly across multiple established oligonucleotide assay types and adjust to fill the week’s study demand.
  
• Data integrity: Review and handling of analytical data in line with the customer’s quality and compliance expectations.
  

• Routine maintenance: Preventive maintenance, QC checks, and consumable management for in-scope LC–MS systems.
  
• First-line triage: Real-time diagnosis and resolution of minor issues at the bench — for example, power cycling, basic troubleshooting, and user-level repairs such as addressing a crashed LC needle.
  
• Hardware lifecycle: Coordination of hardware updates and component replacements as required.
  
• Escalation: Defined troubleshooting and escalation paths, routing repairs that exceed user-level scope to the appropriate vendor service organization (e.g., SCIEX).
  

• Software maintenance: Management of instrument software updates, patching, and version control.
  
• Computer & operating system updates: Deployment of workstation operating system updates, security patching, and configuration changes on instrument-controlling computers, coordinated with the customer’s IT function to avoid disruption to acquisition.
  
• License administration: Tracking and administration of instrument software licenses to maintain continuity of operation.
  

• Visible support: A consistent, approachable presence within the laboratory areas, supplemented by responsive communication via the customer’s collaboration tools.
  
• Vendor escort & coordination: Escorting and hosting instrument vendors on-site, and coordinating with the customer’s analytical and laboratory support functions.
  
• Instrument readiness: Preparing instruments for relocation, decommissioning, or related activities.
  

• Assay execution: Support of established small-molecule DMPK bioanalytical workflows, including sample preparation, bioanalysis, and data review.
  
• Workflow flexibility: Ability to ramp across multiple established small-molecule assay types and absorb overflow demand.
  
• Prioritization: Small-molecule work is scheduled around oligonucleotide bioanalysis and instrument support commitments, and is agreed with the customer on a weekly basis.
  

• Familiarity with bioanalytical workflows — sample preparation, bioanalysis, and data review — with the ability to ramp quickly across multiple established assay types, including small-molecule DMPK assays.
  
• For at least one of the two resources: demonstrable depth in LC–MS instrument hardware maintenance and user-level repair, together with management of instrument software and instrument-controlling computers — updates, patching, version control, operating system administration, and license administration — sufficient to resolve issues in-house and bridge coverage until vendor service engineers attend site.
  
• Relevant education, or extensive directly relevant hands-on experience in lieu of formal education.
  

• Bachelor's degree or equivalent and relevant formal academic / vocational qualification
  

• Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 6+ years).
  
• In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
  

• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
  
• Able to work upright and stationary and/or standing for typical working hours.
  
• Able to lift and move objects up to 25 pounds.
  
• Able to work in non-traditional work environments.
  
• Able to use and learn standard office equipment and technology with proficiency.
  
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
  
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.