Grail

Director of Software Engineering - Data Platforms - #4919

Grail$224K — $321K *
Enterprise Technology
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • 15+ years of progressive software engineering experience
  • 5+ years in an engineering leadership role managing global teams
  • Ability to interface with executive stakeholders
  • Experience managing large operational budgets
  • Proficient in back-end development and architecture with Java/Spring Boot
  • Deep knowledge of big data technologies like Snowflake and Apache Iceberg
  • Hands-on experience with AI frameworks such as RAG and LLMs
  • Understanding of regulated data fields and associated standards is a plus

Responsibilities

  • Lead and mentor a global engineering team, fostering high performance and continuous learning
  • Own technical roadmap and resource allocation, ensuring strategic milestones are met
  • Champion Agile/Scrum methodologies to enhance feature velocity and software quality
  • Architect and optimize transition to modern cloud-native architectures on AWS
  • Define strategy for big data platforms processing large datasets
  • Oversee performance optimizations for analytical data models
  • Direct integration of AI-driven tools and LLM-enabled features
  • Manage development of RESTful APIs and ETL pipelines for data interoperability

Benefits

  • Flexible work arrangement with minimum on-site requirement
  • Comprehensive medical, dental, and vision coverage
  • 401(k) retirement plan with employer match
  • Generous time-off or vacation policy
  • Access to mindfulness programs
Full Job Description
We are seeking a visionary and execution-focused Director of Software Engineering to lead our Data Platform engineering organization. In this role, you will drive the technical strategy, architecture, and delivery of our next-generation, cloud-native data platform.

The ideal candidate brings over 15 years of software engineering experience, combining deep technical expertise in big data, cloud infrastructure, and AI-driven workflows (including RAG and LLM applications) with a proven track record of scaling engineering teams (10+ headcount). You will collaborate closely with cross-functional executives to translate complex domain requirements into scalable, secure, and compliant production-grade software.

This role is based in Sunnyvale, California. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. At our Sunnyvale campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities but candidates must be flexible based on the needs of the business.

Responsibilities

Engineering & Organizational Leadership
  • Team Scaling & Culture: Lead, mentor, and scale a multi-disciplinary global engineering organization, fostering a culture of high performance, continuous learning, and technical excellence.
  • Strategic Roadmap Delivery: Own the technical roadmap and resource allocation, ensuring 95%+ on-time execution of strategic product milestones.
  • Agile Transformation: Champion and mature Agile/Scrum methodologies to optimize feature velocity, minimize product turnaround time, and maintain high software quality.
Strategic Technical Architecture & Data Innovation
  • Cloud-Native Evolution: Architect, govern, and optimize the transition to modern serverless and microservices architectures on AWS, driving structural cost optimization and system elasticity.
  • Big Data Ecosystems: Define the strategy for next-generation big data platforms utilizing Snowflake, Databricks, Apache Iceberg, AWS Glue, etc. to process, partition, and index petabyte-scale datasets.
  • Performance Engineering: Oversee analytical and search data model optimizations to continually improve query performance and data pipeline throughput.
AI & Product Modernization
  • AI-Driven Initiatives: Direct the integration of AI-assisted SDLC tools and architect LLM-enabled product features, including RAG-based semantic search and conversational search workflows.
  • API & System Interoperability: Oversee the development of high-throughput ETL pipelines and secure, scalable RESTful APIs built on Java / Spring Boot to ensure global data interoperability.
Operational Excellence & Compliance
  • DevOps & SRE Practices: Mature CI/CD automation pipelines using infrastructure-as-code (Terraform, Ansible, Jenkins) to automate provisioning and security patching.
  • Security & Compliance: Ensure all platforms strictly adhere to modern cybersecurity standards and regulatory compliance frameworks (e.g., GDPR, HIPAA).


Required Qualifications

Leadership & Soft Skills
  • 15+ years of progressive experience in software engineering, with 5+ years in a dedicated engineering leadership role managing cross-functional, global teams.
  • Proven ability to interface with executive stakeholders (Product, UX, Architecture) to align engineering outputs with business growth.
  • Strong experience managing large operational budgets and implementing strategic cloud cost-optimization practices.
Technical Stack & Domain Expertise
  • Backend & Architecture: Expert-level knowledge of Java, Spring Boot, Spring MVC, distributed systems design, database sharding, and high-performance microservices.
  • Data & Analytics: Deep proficiency with Snowflake, Apache Iceberg, AWS Glue, Spark, and Elasticsearch.
  • AI & Search: Hands-on architecture experience with Retrieval-Augmented Generation (RAG), Large Language Model (LLM) frameworks, and semantic/conversational search.
  • Cloud & DevOps: Strong expertise in AWS Cloud infrastructure, containerization, and IaC tools (Terraform, Ansible, Jenkins).
  • Domain Interoperability: Experience in high-volume, regulated data fields (e.g., genomics, healthcare, bioinformatics, or fintech) and data standards (e.g., GA4GH) is highly desirable.
Education
  • Master's Degree in Computer Science, Software Engineering, or a highly related technical field preferred.
  • Bachelor's Degree in Computer Science or Engineering or equivalent practical experience.


The expected, full-time, annual base pay scale for this position is $224k-321k in Sunnyvale, CA

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate's qualifications. Employees in this role are also eligible for GRAIL's comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

About Grail

Grail is a healthcare company that develops and commercializes blood tests for early cancer detection. The company's tests use a combination of machine learning, genomics, and clinical data to detect cancer at an early stage, when it is most treatable. Grail was founded in 2016 and is headquartered in Redwood City, California.
Learn more about Grail
Size
500 employees
Industry
Founded
2016

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