Ultragenyx Pharmaceutical

Director, Commercial Operations & Strategy

Ultragenyx Pharmaceutical$235K — $291K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Business, Finance, Economics, Life Sciences, or related discipline.
  • 10+ years of experience within the biopharmaceutical industry.
  • Direct experience in Market Access or Pricing, with exposure to pricing governance.
  • Proven ability to lead complex initiatives in global, matrixed organizations without direct authority.
  • Strong analytical, financial, and executive reporting skills, including proficiency in Power BI and Excel.
  • Solution-oriented mindset with a knack for turning problems into actionable strategies while maintaining relationships.
  • Experience with global pricing governance frameworks and distributor-based commercial models.

Responsibilities

  • Own the operational leadership of the Pricing Operations Group, driving agenda-setting and decision framing.
  • Develop and manage the global pricing tracker and reporting infrastructure for data integrity and access control.
  • Steward pricing corridor frameworks and lead continuous improvement of governance processes.
  • Lead the forecast consensus process, ensuring a reconciled view of demand and assumptions.
  • Enhance forecast transparency through collaboration with Commercial, Finance, and Supply chain partners.
  • Manage the Global Commercial KPI governance framework alongside Finance to define metrics and data sources.
  • Create executive dashboards and insights that connect data to actionable business outcomes.
  • Support strategic decision-making with analyses and business cases relating to commercial implications.

Benefits

  • Generous vacation time and public holidays.
  • Volunteer days to support community involvement.
  • Long-term incentive and employee stock purchase plans.
  • Employee wellbeing and fitness reimbursement programs.
  • Tuition sponsorship for continuing education.
  • Professional development plans to enhance career growth.
Full Job Description
Position Summary:

ultrainnovative - Tackle rare and dynamic challenges

Reporting to the VP, Global Commercial Operations & Strategy, the Director leads operationalization of Ultragenyx's global commercial governance model, with primary focus on global pricing governance and commercial planning.

Scope:
  • Global remit spanning North America, Latin America, EMEA, and APAC, covering in-line commercial products and pre-launch assets
  • Accountable for enabling decision-making across pricing, forecasting, commercial analytics, portfolio prioritization, and distributor governance
  • Operates across Commercial, Finance, Supply Chain, Market Access, and Regional organizations to drive enterprise alignment

The role interfaces regularly with senior leadership through governance forums and executive materials, working in close partnership with function and Region teams.

The role sits within a small, collaborative team that values clarity, pragmatism, and constructive problem-solving. The successful candidate will bring a solid grounding in pricing or market access and the appetite to broaden across commercial, the operational rigor to institutionalize governance forums, and the strategic judgment to facilitate thoughtful, high-impact decisions-and will be someone others genuinely want to work with on complex problems.
Work Model:

Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.
Responsibilities:
  1. Own the operational leadership of the Pricing Operations Group - agenda-setting, decision framing, team coordination, materials, and executive escalation - in support of pricing decisions owned by Market Access and Commercial partners.
  2. Build and steward the global pricing tracker and reporting infrastructure, leading collection, validation, and reporting of pricing information with Regional and Market Access teams under disciplined controls on data sensitivity and access.
  3. Steward pricing corridor frameworks, approval thresholds, and exception management processes, and drive continuous improvement of pricing governance as the portfolio and geographic footprint evolve.
  4. Lead the operational cadence of the forecast consensus process and own the forecast assumptions log and change-control process, ensuring a single, traceable, and reconciled view of demand.
  5. Partner with Commercial, Finance, and Supply teams to improve forecast transparency, reconciliation quality, and organizational alignment.
  6. Lead ongoing operation of the Global Commercial KPI governance framework, in partnership with Finance, including metric definitions, ownership, calculation logic, data sources, cadence, and reconciliation rules.
  7. Partner with functions and Region teams to develop executive dashboards and performance narratives that connect data to business implications and recommended actions.
  8. Support enterprise investment and prioritization decisions through structured analyses, business cases, and executive decision materials, and assess the commercial implications of strategic alternatives and resource-allocation trade-offs.
  9. Partner with Regional teams and the VP, Global Commercial Operations & Strategy to design and stand up the global distributor governance framework, codifying performance standards, oversight cadence, escalation paths and best practice sharing.
Requirements:
  1. Bachelor's degree in Business, Finance, Economics, Life Sciences, or related discipline.
  2. 10+ years of experience within the biopharmaceutical industry.
  3. Direct experience in Market Access and/or Pricing (including Pricing Operations), with demonstrated exposure to pricing governance or global pricing decision-making.
  4. Demonstrated ability to lead complex initiatives without direct authority in global, matrixed organizations.
  5. Strong analytical and financial acumen, including comfort with Power BI, Excel-based analytics, and executive reporting tools.
  6. Solution-oriented approach to ambiguous problems - with a demonstrated ability to move from problem identification to actionable path forward while maintaining constructive relationships
  7. Strong executive communication and presentation skills; ability to translate analysis into recommendations for senior leadership.
  8. Direct experience operating within global pricing governance frameworks (corridors, thresholds, exception management)
  9. Experience partnering with or working within Global Market Access, HEOR, or Pricing & Reimbursement functions, including launch pricing decisions for rare disease, specialty pharmaceutical, biotechnology, or gene therapy products
  10. Experience with commercial forecasting, business planning, performance management, product launch planning, and distributor-based commercial models
  11. Prior experience in management or strategy consulting with a life sciences focus (particularly in pricing, market access, or commercial excellence), combined with substantive biotech experience.

#LI-CS1 #LI-Hybrid

The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location.

This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment.

Pay Range

$235,700-$291,200 USD

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

• Generous vacation time and public holidays observed by the company

• Volunteer days

• Long term incentive and Employee stock purchase plans or equivalent offerings

• Employee wellbeing benefits

• Fitness reimbursement

• Tuition sponsoring

• Professional development plans

* Benefits vary by region and country

About Ultragenyx Pharmaceutical

Ultragenyx Pharmaceutical is a biopharmaceutical company that develops and markets treatments for rare and ultra-rare genetic diseases. The company's products are designed to address the underlying genetic causes of these diseases. Ultragenyx Pharmaceutical was founded in 2010 and is headquartered in Novato, California. The company has a number of products in development, including treatments for lysosomal storage disorders, metabolic disorders, and skeletal disorders. Ultragenyx Pharmaceutical is committed to improving the lives of patients with rare diseases and has received numerous awards for its work in this area.
Learn more about Ultragenyx Pharmaceutical
Size
1,119 employees
Market Cap
$3 billion
Industry
Net Income
-$186.5 million
Founded
2010
5 Year Trend
+383.5%
Revenue
$271 million
NASDAQ

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