Job title: Clinical Real World Data Scientist/ Methodologist
- Location: US Bridgewater / Morristown
Main ResponsibilitiesYou will be responsible for designing the methodology to evaluate the fitness-for-purpose of real-world data (RWD) sources for insights or evidence generation, support the development of reliable RWD Foundation and Products. This role serves as a methodological authority and RWD data domain expert, ensuring best-in-class data selection and optimal data usage to generating reliable insights or evidence to better understanding gaps in patient care and healthcare providers involved in patient care. This role is key to ensure data-drive decision is reliable, trustworthy, and timely.
Data Assessment & Fitness-for-Purpose Evaluation- Lead and execute feasibility assessments for RWD sources (electronic health records, administrative claims, patient registries, wearable/digital health data) to determine suitability for specific research/business objectives
- Develop and apply structured data assessment frameworks to evaluate data quality dimensions, including accuracy, completeness, validity, timeliness, longitudinally consistency, and integrity
- Assess the availability and representativeness of patient populations within RWD sources available in Sanofi for both internal decision-making and regulatory-grade evidence generation
- Evaluate the feasibility of extracting structured and unstructured data elements (e.g., clinical scores, patient-reported outcomes) from EHR systems, including NLP-based extraction from clinical notes
- Document assessment outcomes in standardized feasibility reports and communicate findings clearly to cross-functional stakeholders
- Identify and articulate limitations of RWD sources, such as proxy endpoint constraints, population coverage gaps
Methodological Design & Optimal RWD Usage- Design methodologically sound recommendations & minimize misuse of RWD, leading to unreliable insights or evidence generation
- Ensure appropriate use of ICD codes, procedure codes, and other medical coding standards (sourced from peer-reviewed references such as PubMed, Embase, and Orphanet, etc.) for patient identification, healthcare provider segmentation, clinical site identification, and phenotyping
- Apply advanced epidemiological and biostatistical methods including propensity score methods, time-to-event analyses, sensitivity analyses, and bias assessment
- Provide methodological input on the use of clinical score proxies and surrogate endpoints in RWD contexts, clearly delineating their applicability for internal versus regulatory/publication use
- Provide methodology advises ensuring deliverables from RWD Foundation, RWD Science, and RWD Products are based on medical evidence/guidelines, clinically & contextually relevant
- Work closely with analysts & data scientists to ensure methodological recommendation is realistic and implementable
Cross-Functional Collaboration & Stakeholder Engagement- Partner with R&D, Business units (Vaccines, General Medicine and Specialty Care) & Digital teams on data identification and appropriate usage of RWD for insights / evidence generation across drug lifecycle
- Serve as the methodological point of contact for fit-for-purpose data assessment inquiries from internal stakeholders
- Collaborate with RWD Foundation, RWD Product Owners, RWD Data Sciences to ensure RWD are used appropriately to inform reliable decision making & to provide knowledge transfer on data domain expertise
- Manage external data vendors and technology partners (e.g., EHR, claims, registries) to understand data limitations and to verify methodological recommendations when required
NOTE: This role does not conduct real-world evidence studies.About YouQualifications- Advanced degree (Master's or PhD) in Epidemiology, Biostatistics, Health Informatics, Health Economics, Pharmacoepidemiology, or a closely related quantitative discipline
- Minimum 4-5 years for Master's degree holder or 2-4 years for Doctoral degree holder of relevant experience in real-world data, commercial analytics, real-world evidence, health outcomes research, fit-for-purpose feasibility assessment, data quality assessment or a related field within the pharmaceutical, biotech, or health technology industry
- Experience in predictive modeling using RWD to identify at risk patient populations with a publication record in peer-review journals
- Experience in patient & healthcare provider segmentation to inform Medical and Commercial strategy
- Demonstrated expertise in epidemiological study design and statistical methods such as propensity score matching, descriptive statistics, regression analysis, predictive modelling.
- Strong proficiency in statistical programming languages: SQL, Python, R, and/or SAS
- Solid working knowledge of Snowflake for database querying and data extraction
- Familiarity with medical coding systems: ICD-10, CPT, SNOMED CT, LOINC, RxNorm and experience/knowledge on OHDSI OMOP CDM standardized data model for healthcare data
- Understanding of US EHR, claims, disease registry data, public health surveillance data as well as US healthcare billing system
- Experience with AI coding tools such as Cursor, GitHub Copilot, Claude, LLM
- Knowledge of automation tools such as Power Automate, Power App (an asset not required)
- Requires a high level of interactive communication with diverse stakeholders
- Can work with assumptions & in a fast-paced environment
- Proven teamwork and collaboration skills
The salary range for this position is:
$100.500,00 - $145.166,66
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.
