Chief of Staff

Probably Genetic

• $160K — $200K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • 8+ years of experience in management consulting and high-growth startups
  • Experience managing fundraising processes (Series A>D) and understanding investor relations
  • Proven ability to operate at the intersection of strategy and execution
  • Background in healthtech or biotech, or experience in complex industries
  • Meticulous attention to detail with high standards for output
  • Demonstrable AI literacy and ability to lead others in using AI tools
  • Exceptional written communication skills
  • Ability to manage multiple priorities in dynamic environments
  • High emotional intelligence and leadership presence
  • Collaborative, low-ego operating style

Responsibilities

  • Own end-to-end venture fundraising due diligence and investor outreach
  • Serve as primary coordination point between CEO and investors
  • Prepare board meeting materials and manage follow-ups
  • Draft investor updates and strategic communications
  • Reduce CEO's operational overhead by managing recurring processes
  • Lead cross-functional projects ensuring clarity and outcomes
  • Identify organizational bottlenecks and build scalable processes
  • Prepare CEO for key meetings with background briefs and documentation
  • Own preparation and execution for board meetings and external communications

Benefits

  • Engaging and supportive team focused on improving lives
  • Fair and equitable compensation with competitive equity grants
  • Generous flexible time off policy
  • Parental leave benefits for both birthing and non-birthing parents
  • Hybrid, flexible work environment with high trust
  • Bright, pet-friendly office in Downtown SF
  • Company-sponsored team lunches every Thursday
  • Work from anywhere policy for up to 4 weeks a year
  • Regular team retreats in exciting destinations
  • Comprehensive health benefits including medical, dental, vision, and 401k
Full Job Description
About the role

We are at an inflection point. With a Series B on the horizon and a growing portfolio of partnerships with drug developers and patient advocacy groups, we need a Chief of Staff who can operate as a true right hand to the Founder and CEO - someone who runs toward complexity, brings structure to ambiguity, and holds the highest standards of craft and detail.

You will own high-stakes initiatives, manage venture fundraising end-to-end alongside the CEO, and serve as a force multiplier across the leadership team. If you have thrived in fast-moving, dynamic environments and want your work to directly improve patient outcomes, this is the role for you.

What you will do

Venture fundraising & existing investor relations (20%)
  • Own the end-to-end venture fundraising due diligence: materials, data room, investor outreach, pipeline management, and follow-through
  • Serve as the primary point of coordination between the CEO and prospective and existing investors
  • Prepare board meeting materials, manage the board cadence, and ensure follow-ups are tracked and closed
  • Draft investor updates, pitch narratives, and other strategic communications with precision and clarity

CEO leverage, strategic though partnership & cross-functional execution (40%)
  • Reduce CEO time on operational overhead by 30%+ by owning recurring processes, decision tracking, and stakeholder communication
  • Lead cross-functional projects that span multiple teams, ensuring clarity of ownership, timelines, and outcomes
  • Identify bottlenecks across the organization and build scalable processes to address them before they become problems
  • Prepare the CEO for key meetings with background briefs, talking points, and follow-up documentation

Strategic external communications (40%)
  • Own end to end preparation and execution for quarterly board meetings and mid-quarter check-ins
  • Draft external communications on behalf of the CEO, including company-wide updates, partner communications, and thought leadership via a variety of social channels
  • Ensure data and messaging is consistent and reflects the company's mission and values by creating a consistent framework for use by CEO and broader Leadership Team
Who you are

We are looking for a few specific things that will help you succeed in this role:
  • 8+ years of experience, with a strong foundation in management consulting (McKinsey, BCG, Bain, or equivalent) and subsequent operating experience at a high-growth startup
  • Prior experience supporting or managing a fundraising process (Series A>D ideally); demonstrated understanding of investor relations and venture dynamics
  • Track record of operating at the intersection of strategy and execution - you are as comfortable in a boardroom as you are building a process from scratch
  • Experience in healthtech or biotech or track record of operating in highly complex industries
  • Meticulous attention to detail - you catch errors others miss and hold every output to an exceptionally high standard
  • Proven, demonstrable AI literacy - you actively use AI tools (beyond prompting) in your daily workflow and can lead others in doing the same
  • Exceptional written communication - you write with clarity, economy, and impact
  • Skilled at managing multiple shifting priorities without dropping the ball - you thrive in dynamic environments where the roadmap changes week to week
  • High emotional intelligence and leadership presence - you know when to push, when to listen, and how to build trust quickly
  • A collaborative, low-ego operating style - you care about outcomes, not credit

As with all new hires at Probably Genetic, you will also need to be:
  • A good person. We work with some of the most marginalized populations on the planet and empathy is key
  • Patient-focused and motivated to have a lasting, positive impact on humanity
  • Comfortable in a fast-paced, often ambiguous environment with rapid change
  • Action-oriented and excited to build a company from the ground up
What we offer at Probably Genetic:
  • An engaging and supportive team all on a mission to improve lives
  • Fair and equitable compensation with competitive early-stage equity grants
  • Generous Flexible Time off policy, that we actually use
  • Parental Leave Benefits (12 weeks for both birthing and non-birthing)
  • Hybrid, flexible work with high-trust and autonomy
  • A bright, inviting, pet-friendly office in Downtown SF near transit
  • Company-sponsored team lunch every Thursday
  • A "work from anywhere" policy, up to 4 weeks a year
  • Regular team retreats in exciting destinations
  • Health Benefits including medical, dental, vision, therapy, FSA, and 401k
  • And so much more!

Similar Jobs

More Jobs at Probably Genetic

  • Chief of Staff
    $160K — $200K *
    San Francisco, CA 94112 (San Francisco County)
    Pharmaceuticals & Biotech
    In-Person
  • Senior Product Manager
    $155K — $210K *
    San Francisco, CA 94112 (San Francisco County)
    Pharmaceuticals & Biotech
    In-Person
  • Senior Software Engineer
    $150K — $210K *
    San Francisco, CA 94112 (San Francisco County)
    Healthcare
    In-Person
  • Head of Community Marketing
    $120K — $185K *
    San Francisco, CA 94112 (San Francisco County)
    Healthcare
    In-Person

More Pharmaceuticals & Biotech Jobs

Find similar Chief of Staff jobs: