OverviewThe Cellular Therapy Lab (CTL) at the Fred Hutch Cancer Center is on the cutting edge of new technologies for cancer therapy, including cell-based immunotherapy. We are committed to advancing treatment options for our patients through the translation of innovative research into clinical practice. We collaborate with our consortium partners (University of Washington and Seattle Children's Hospital) as well as industry (biotechnology) and non-industry external entities.CTL is responsible for all minimally manipulated therapeutic cell processing occurring at the Fred Hutch. Procedures range from cryopreservation to flow cytometric enumeration of cell proportions to more complex procedures such as cell selection, enrichment, and depletion. The laboratory is regulated by the Food and Drug Administration (FDA) cGTP/cGMP standards, maintains College of American Pathologists (CAP) certification, and is accredited by the Joint Commission and the Foundation for the Accreditation of Cellular Therapy (FACT).
At Fred Hutchinson Cancer Center, all employees are expected to demonstrate a commitment to our values of collaboration, compassion, determination, excellence, innovation, integrity, and respect.
The schedule for this position will be 1.0FTE/full-time Monday-Friday from 11:30am-8pm.
Responsibilities
- Process cellular products/specimens according to standard operating procedure (SOP), and specific guidance for clinical trials, using aseptic technique
- Perform and analyze results of quality control testing of components, including automated nucleated cell counts and flow cytometry
- Document processing steps accurately, generate processing reports and prepare patient/donor laboratory charts; review processing reports and charts
- Understand and stay current with SOPs as needed, and perform SOP qualifications. Provide input/feedback to Lab Supervisor on documentation and process improvements
- Thaw cryopreserved components and assist with infusion at the patient bedside
- Meet unrelated donor (URD) component couriers and perform necessary testing and processing of components prior to release
- Potentially assist with the bone marrow collection within operating rooms
- Perform clinical trials processing:
- CliniMACS4 cell selection e.g. CD34+ cell enrichment, CD3+ cell depletion
- CAR-T therapy processing and cryopreservation
Qualifications
Required:
- Four-year college degree with major in biological science or related degree
- Basic hematology knowledge
- Motivation and initiative to learn new scientific theory and applications
- Mature judgment
- Work independently with moderate supervision
- Proven team player
- Collaborate and communicate effectively across functions
- Interpret data thoroughly
- Strong trouble-shooting capabilities
- Scientific writing skills, including preparation of clear, concise SOPs and technical reports
- Strong math skills
- Strong communication skills
- Attention to detail
- Flexibility in scheduling: night, weekend, holiday and on-call rotations
- Must be able to differentiate between colors and pass a standardized color vision screen to perform this role
Preferred:
- Bachelor's degree in a chemical, biological, clinical or medical laboratory science, or medical technology from an accredited institution or a Bachelor's degree and equivalent education and training as defined in 42CFR493.1489(b)(3)(ii). Meets the CLIA education requirements for a high complexity testing
- Advanced knowledge of oncology, hematology and/or immunology
- Flow cytometry expertise
- Immunotherapy experience
- CliniMACS4 operation experience
- Surgical tech experience
- LabWare LIMS knowledge
- A good understanding of cGMP/cGTP standards
- Proven record of completing projects efficiently and effectively
- Flow cytometry expertise
- Immunotherapy experience
- CliniMACS4 operation experience
- LabWare, LIMS knowledge
- A good understanding of cGMP/cGTP standards
The hourly pay range for this position is from $38.69 to $58.02 and pay offered will be based on experience and qualifications.Although Fred Hutch is not sponsoring most H-1B visas at this time, candidates who already hold an H-1B sponsored by another organization and are currently in the U.S. may be eligible for this position.Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks).
