Job DescriptionJob Title: Associate ScientistLocation: Boston / Cambridge, MAAbout the role:The Associate Scientist will support the advancement of GIDDU programs through in vitro pharmacology and assay development. In this role, you will design, execute, interpret, and document studies using primary human immune cells to generate high-quality, reproducible data that supports program decisions and development-stage activities. You will bring hands-on expertise in multi-parameter flow cytometry, primary cell culture, and in vitro pharmacology assays while collaborating with cross-functional research and development teams to address technical challenges and advance scientific programs.
How you will contribute:- Lead the design, optimization, execution, and interpretation of in vitro pharmacology assays supporting GIDDU programs.
- Design and perform experiments using primary human immune cells, including culture, stimulation, treatment, phenotyping, and functional readouts.
- Support the development, troubleshooting, qualification, and analysis of multi-parameter flow cytometry assays to evaluate mechanism of action, target engagement, and immune cell phenotypes.
- Generate reproducible, high-quality data to support program decisions and development-stage activities.
- Contribute to study design, protocol execution, data analysis, and preparation of study reports.
- Maintain accurate, complete, and inspection-ready experimental records aligned with data integrity expectations.
- Prepare technical summaries, figures, reports, and presentations that clearly communicate data, limitations, and conclusions.
- Partner with internal research, translational, biologics, regulatory, and project teams to ensure studies meet program needs.
- Identify technical challenges, troubleshoot assays, and propose practical solutions to maintain study progress.
- Contribute to project team discussions and support scientific decision-making.
What you bring to Takeda:- Bachelor's degree in Immunology, Cell Biology, Molecular Biology, Biotechnology, Pharmacology, or a related discipline with 8+ years of relevant experience, or a Master's degree with 4+ years of relevant experience.
- Hands-on experience designing and executing in vitro assays using primary human immune cells.
- Experience executing and analyzing multi-parameter flow cytometry assays, including panel design, staining, acquisition, compensation, gating, troubleshooting, and analysis.
- Experience generating reproducible pharmacology data and clearly documenting experimental results.
- Strong scientific writing skills, including preparation of study summaries, technical reports, figures, and presentations.
- Experience supporting development-stage studies or pharmacology data packages; experience with antibody-based therapeutics, CD38 biology, B cell or plasma cell biology, or immune-mediated disease pharmacology is preferred.
- Experience with target engagement, receptor occupancy, immune cell depletion, cytokine, proliferation, or viability assays, along with familiarity with assay qualification, reproducibility standards, and data documentation practices.
Takeda Compensation and Benefits SummaryWe understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:Boston, MA
U.S. Base Salary Range:$103,500.00 - $162,690.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
For information about our benefits, please click here.
LocationsBoston, MA
Worker TypeEmployee
Worker Sub-TypeRegular
Time TypeFull time
Job ExemptYes
