Associate Scientist II/Senior Associate Scientist Biology

Iambic Therapeutics, Inc

$90K — $120K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or master's degree in biochemistry, pharmacology, cell biology, or related fields
  • 2+ years of industry experience for Associate Scientist II; 5-8 years for Senior Associate Scientist
  • Hands-on expertise in routine biological assays including cell culture and ELISA
  • Proficiency in proximity-based assays (HTRF, NanoBRET, AlphaLISA) preferred
  • Familiar with high-throughput screening methodologies
  • Strong data evaluation skills and scientific rigor
  • Excellent oral and written communication skills

Responsibilities

  • Collaborate to design and optimize biochemical and cell-based assays
  • Execute assays weekly to screen small-molecule compounds
  • Coordinate compound screening with Biology, Chemistry, and Compound Management teams
  • Analyze experimental data ensuring scientific rigor
  • Present results and updates in team meetings
  • Ensure QC and timely upload of experimental data
  • Maintain and manage cell lines for ongoing projects

Benefits

  • Company-paid healthcare
  • Flexible spending accounts
  • Voluntary life insurance
  • 401K matching
  • Uncapped vacation
  • State-of-the-art facilities with onsite gym and dining options
Full Job Description
JOB SUMMARY

We are seeking a highly motivated and experienced Senior Associate Scientist to join the Biology group and advance our core mission of accelerating small molecule drug discovery programs at Iambic Therapeutics. The successful candidate will have a proven track record of supporting in vitro cell-based assays to advance pre-clinical projects. The candidate will work closely with a cross-functional team that integrates machine learning, medicinal chemistry, analytical technology and biology to revolutionize small-molecule therapeutics design and discovery. This role is based at our San Diego headquarters.

KEY RESPONSIBILITIES
  • Design, develop, and optimize biochemical and cell-based assays to support multiple drug discovery programs, working closely with project teams and cross-functional partners.
  • Independently execute biochemical and/or cell-based assays on a weekly basis to screen and evaluate small-molecule compounds
  • Partner with Chemistry and Compound Management teams to enable efficient compound screening across pipeline projects.
  • Analyze and interpret experimental data and ensure scientific rigor and data quality
  • Partner with cross-functional teams to QC and upload experimental data in a timely manner
  • Present experimental results and project updates at team meetings
  • Maintain and manage cell lines to support ongoing research projects
  • Contribute to the maintenance of the biology laboratory


QUALIFICATIONS
  • Associate Scientist II- Bachelor's degree in biochemistry, pharmacology, cell biology, or other related scientific areas with a minimum of 2- years of industry experience
  • Senior Associate Scientist- Bachelor's degree in biochemistry, pharmacology, cell biology, or other related scientific areas with a minimum of 5 years of industry experience
  • Hands-on experience in cell biology and routine biological assays, including techniques such as cell culture, cell proliferation assays, cytotoxicity assays, ELISA, and Western blot,
  • Experience with proximity-based assays is highly desirable (e.g., HTRF, NanoBRET, AlphaLISA)
  • Familiarity with HTS screening methodology is highly desirable
  • Demonstrated scientific rigor with proven ability to critically evaluate data, and think independently and creatively in developing and testing new scientific hypotheses
  • Excellent oral and written communication skills is required
  • Highly motivated to work in a cross-functional team setting
  • Flexibility and ability to quickly learn new skills and knowledge on the job


PAY AND BENEFITS

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

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