Job Description
Our Research and Development Division in San Diego is a cross-functional team (Discovery Biologics, Immunology, and Data Science) with the goal to discover and develop novel, innovative therapeutics in the field of Inflammation and Immunology. The Discovery Biologics Department is seeking a Scientist with expertise in protein design, production and characterization to contribute to our Biologics portfolio. This position offers a great opportunity to be a part of the early scientific team, and a key interface within the global Discovery Biologics network and with Immunology and other functions across our company.
The successful candidate will carry out experiments in the lab to build and support projects in the early discovery pipeline, with focus on innovative antibody-based therapeutics. We recognize that the diversity in our team is our strength and are dedicated to creating an inclusive environment for all employees. Successful candidates should demonstrate attention to detail, ability to work efficiently and collaboratively, a desire to learn, and be adaptable to thrive in a dynamic team environment.
Key Responsibilities:
Express and purify therapeutic proteins, target antigens and the critical protein reagents required for advancing our biologics discovery programs
Test and characterize the developability of therapeutic proteins
Screen novel therapeutic protein designs in biochemical and cell based assays
Drive innovation by contributing to exploratory programs and platform technology development.
Collaborating with teams on portfolio programs
QUALIFICATIONS:
Education:
Required Experience and Skills:
Proficiency in protein purification methods including affinity chromatography, Ion exchange chromatography, and size exclusion chromatography
Expertise culturing mammalian cells and utilizing for protein expression
Experience generating protein expression constructs including vector selection, cassette design, cloning and validation.
Demonstrated strong communication skills and ability to multi-task and work collaboratively in a cross-functional team environment.
Excellent organizational skills and high attention to detail.
Preferred Experience and Skills:
Previous experience in protein binding assays including ELISA, our company and cell-based binding assays
Experience in stable expression systems
Experience with high throughput technologies and automation platforms
#EligibleforERP
Required Skills:
Chromatography, Cloning, Mammalian Cell Culture, Protein Expression, Protein Purification Methods, Validation, Vector Analysis
Preferred Skills:
Current Employees apply
Current Contingent Workers apply
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please if you need an accommodation during the application or hiring process.
The salary range for this role is
$87,300.00 - $137,400.00
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at .
You can apply for this role through (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
Regular
Relocation:
Domestic
VISA Sponsorship:
No
Travel Requirements:
No Travel Required
Flexible Work Arrangements:
Not Applicable
Shift:
1st - Day
Valid Driving License:
No
Hazardous Material(s):
n/a
Job Posting End Date:
07/2/2026
*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
