Analytical Development Principal Research Scientist

Vertex Pharmaceuticals

$140K — $211K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. with 4-7 years, Master's with 7+ years, or Bachelor's with 10+ years of relevant experience in analytical development.
  • Proven experience in preclinical to Phase 1 drug development in the pharmaceutical or biotechnology sector.
  • Strong technical expertise in analytical techniques such as LC, GC, KF, NMR, and XRF.
  • Demonstrated troubleshooting and problem-solving skills in a laboratory setting.
  • High attention to detail and strong analytical data assessment capabilities.

Responsibilities

  • Represent Analytical Development at cross-functional teams and communicate issues and solutions effectively.
  • Develop, align, and execute analytical project team strategies for drug development.
  • Apply advanced analytical skills and techniques for drug substance and product analyses.
  • Collaborate effectively within a matrix team environment while also being capable of independent work.
  • Present technical results clearly in both oral and written formats.

Benefits

  • Comprehensive medical, dental, and vision benefits.
  • Generous paid time off, including a week-long company shutdown yearly.
  • Educational assistance programs, including student loan repayment support.
  • 401(k) matching and a generous commuting subsidy.
  • Flexible work options with onsite requirements and ad hoc flexibility.
Full Job Description
Job Description

General Summary:

Vertex is seeking a talented scientist to join our small molecules Analytical Development group in Boston, MA. This individual will play a central role in advancing transformative medicines by leading analytical chemistry activities for small molecule development programs from preclinical through to Phase 1. This role includes representing Analytical Development at cross-functional project team meetings and so demonstrable experience to resolve project challenges in collaboration with other R&D functions is required. The ability to work both independently and in a matrix team environment is essential to succeed in this position.

Key Duties and Responsibilities:

  • Project oversight: represent Analytical Development at cross-functional teams and effectively communicates issues and solutions to colleagues at all levels within the organization.
  • Strategy: develop, align and execute analytical project team plans and strategies to support drug substance and drug product development including method development, stability and validation activities.
  • Laboratory expertise: apply advanced analytical skills and understanding in laboratory techniques routinely used in the analysis of drug substance and drug product samples.
  • Collaboration: work both independently and collaboratively within a matrix team environment.
  • Communication: demonstrated ability to effectively present results in both oral and written reports and to productively disseminate ideas across discipline and project boundaries.
  • Advance strategic initiatives: develop, contribute and support new ways of working, operating models and paradigms that improve productivity, efficiency and overall effectiveness of workflows and processes


Knowledge and Skills:
  • Experienced Analytical Lead (preclinical to Phase 1) in the pharmaceutical or biotechnology industry
  • The ability to work successfully in both a team/matrix environment as well as independently
  • Technical expertise in analytical techniques that include LC, GC, KF, NMR, XRF etc
  • Advanced troubleshooting skills and problem-solving capabilities
  • Strong analytical data assessment, review and interpretation skills
  • Advanced experience in communication of technical data: writing reports and presentation skills
  • High attention to detail
  • Ability to work in a fast-paced environment, managing priorities and maintaining timelines
  • Strong knowledge of cGMPs and pharmaceutically relevant regulatory guidelines


Education and Experience:
  • Ph.D. with 4-7 years, Master's degree with 7+ years, or Bachelor's degree with 10+ years of relevant professional analytical development experience in the pharmaceutical industry


Pay Range:
$140,800 - $211,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:
On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

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