Sanofi

2027 Spring Co op Bioanalytics Cambridge MA

Sanofi • $118K *
Cambridge, MA 02139In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
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Job Overview by Ladders

Qualifications

  • Currently pursuing a PhD in biochemistry, biotechnology, pharmaceutical sciences, or related health sciences, expecting graduation by Dec 2028.
  • Permanent authorization to work in the U.S. without future visa sponsorship.
  • Enrolled in an accredited college throughout the co-op duration.
  • Relocation to Cambridge, MA, and ability to work 40 hours/week for 6 months.
  • Strong knowledge of pharmacokinetics (PK) and pharmacodynamics (PD).
  • Proficiency in at least one mass spectrometry platform (high-resolution or triple quadrupole).
  • Experience with protein quantitation extraction techniques.

Responsibilities

  • Design and develop PK LC-MS assays for biologics and AOCs under supervision.
  • Create sample preparation techniques such as protein precipitation and solid phase extraction.
  • Develop LC-MS/MS and LC-HRMS methods for protein analysis.
  • Characterize pharmacokinetic profiles of constructs including integrity analysis.
  • Analyze samples for pharmacokinetic and pharmacodynamic studies.
  • Discuss bioanalytical results in the context of drug development.
  • Contribute to scientific discussions actively.

Benefits

  • Hands-on experience in bioanalytics with drug development implications.
  • Opportunity to work with cutting-edge mass spectrometry technology.
  • Networking opportunities with professionals in the biotech field.
  • Development of practical skills in pharmacokinetic analysis.
  • Potential for collaborative research experiences.
Full Job Description
Job Title: 2027 Spring Co-op Bioanalytics
  • Grade: Co-op
  • Location: Cambridge, MA
  • Duration: 6 months


Main Responsibilities:
  • With supervision, design, develop and fit-for-purpose qualify PK LC-MS assays in preclinical setting for biologics and AOCs (Antibody oligonucleotide conjugates).
  • Develop sample preparation approaches such as protein precipitation, solid phase extraction, Immunoprecipitation, enzymatic digestions etc.
  • Develop LC-MS/MS and LC-HRMS for intact protein analysis, middle-up approach or bottom-up approach.
  • Use these methods to characterize pharmacokinetic profile of constructs, including integrity analysis.
  • Analyze samples to support pharmacokinetic and pharmacodynamic analysis for discovery and preclinical studies.
  • Report and discuss bioanalytical and biomarker results with integrative knowledge of how the data contributes to the drug development process
  • Actively contribute to scientific discussions


About You

Basic Qualifications:
  • Currently pursuing a PhD degree in biochemistry, biotechnology, pharmaceutical sciences or related health sciences at an accredited college or university, with an expected graduation date no later than Dec 2028.
  • Must be permanently authorized to work in the U.S. and not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future. Students currently on CPT, OPT, or STEM OPT usually require future sponsorship for long term employment and do not meet the requirements for this program unless eligible for an alternative long-term status that does not require company sponsorship
  • Must be enrolled in an accredited college or university throughout the duration of the co-op/internship
  • Must be able to relocate to the office location and work 40hrs/week, Monday-Friday, for the full duration of the co-op/internship
  • Knowledge of pharmacokinetics (PK) and pharmacodynamics (PD) concepts and their role in drug development
  • Expertise in at least one mass spectrometry platform: either high-resolution mass spectrometry (time-of-flight or Orbitrap) or triple quadrupole mass spectrometry
  • Good understanding of protein analysis on at least one of the following platforms: Thermo, Waters, or Sciex
  • Experience with at least one extraction technique for protein quantitation in biological matrices (plasma and/or tissues), such as protein precipitation, solid phase extraction, immunoprecipitation, or enzymatic digestion
  • Knowledge of proteomics tools, including protein database queries and protein sequence analysis


Preferred Qualifications:
  • Experience utilizing (AI) artificial intelligence tools for drug discovery and development.
  • Scientific curiosity, appetite for teamwork, and strong problem-solving skills
  • Excellent organizational and documentation skills
  • Good written and oral communication skills along with the ability to work collaboratively in a team setting
  • Demonstrated ability to work independently to develop and/or qualify bioanalytical assays


Compensation

The salary for this position is $57hourly. All compensation will be determined commensurate with demonstrated experience.

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About Sanofi

Sanofi is a global pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs and vaccines. The company operates in over 170 countries and has a diverse portfolio of products that includes treatments for diabetes, cancer, cardiovascular disease, and rare diseases. Sanofi is committed to improving global health and has a strong focus on innovation and sustainability. The company has received numerous awards for its research and development efforts and is recognized as a leader in the pharmaceutical industry.
Learn more about Sanofi
Market Cap
$121.6 billion
Industry
Pharmaceuticals & Biotech
Net Income
$12.3 billion
Founded
1990
5 Year Trend
+2.5%
Revenue
$37.3 billion
NASDAQ
SNYNF
* Ladders Estimates

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