The Cleveland Clinic Foundation is a non-profit academic medical center located in Cleveland, Ohio. It was founded in 1921 and has since become one of the largest and most respected hospitals in the world. The hospital is known for its innovative research and patient-centered care, and has been ranked as the #2 hospital in the United States by U.S. News & World Report. The Cleveland Clinic Foundation employs over 70,000 people and has locations throughout the United States and internationally. The hospital is also a major research institution, with over 3,000 active clinical trials and $1.5 billion in research funding.