Case Western Reserve University is a private research university in Cleveland, Ohio. It was created in 1967 through the federation of two longstanding contiguous institutions: Western Reserve University, founded in 1826 and named for its location in the Connecticut Western Reserve, and Case Institute of Technology, founded in 1880 through the endowment of Leonard Case, Jr. Time magazine described the merger as the creation of "Cleveland's Big-Leaguer" university., The campus is approximately 5 miles east of Downtown Cleveland in the neighborhood known as University Circle, an area encompassing 550 acres containing a concentration of educational, medical, and cultural institutions. Case Western Reserve has a number of programs taught in conjunction with University Circle institutions, including the Cleveland Clinic, the University Hospitals of Cleveland, the Louis Stokes Cleveland Department of Veteran's Affairs Medical Center, Cleveland Institute of Music, the Cleveland Hearing & Speech Center, the Cleveland Museum of Art, the Cleveland Institute of Art, the Cleveland Museum of Natural History, and the Cleveland Play House. Severance Hall, home of the Cleveland Orchestra, is on the Case Western Reserve campus., Case Western Reserve includes the medical school, business school, dental school, law school, Frances Payne Bolton School of Nursing, Department of Biomedical Engineering and its biomedical teaching and research capabilities. Case Western Reserve is a member of the Association of American Universities. Case is noted for research in electrochemistry and electrochemical engineering., The Michelson–Morley interferometer experiment was conducted in 1887 in the basement of a campus dormitory by Albert A. Michelson of Case School of Applied Science and Edward W. Morley of Western Reserve University. Michelson became the first American to win a Nobel Prize in science. Since then, seventeen Nobel laureates have been affiliated with Case Western Reserve or one of its two predecessors.