Explore System Safety Engineer Jobs

System Safety Engineers help organizations identify and reduce risks across complex products, technologies, and operations. Browse vetted opportunities on Ladders, including roles with salaries of $100,000 or more, and discover positions where your expertise can support safer, more reliable systems.

What Does a System Safety Engineer Do?

System Safety Engineers assess hazards throughout a system’s lifecycle, from early design and development through testing, deployment, and ongoing operation. They conduct safety analyses, document risks, recommend controls, and work with engineering and program teams to make safety an integral part of system decisions.

Common Responsibilities and Skills

Responsibilities may include performing hazard analyses, maintaining safety assessments, evaluating system requirements, supporting verification and validation, and helping teams comply with applicable standards and regulations. Employers often value experience with methods such as FMEA, fault tree analysis, and system hazard analysis, along with strong communication and cross-functional collaboration skills.

Industries Hiring System Safety Engineers

Opportunities can be found in aerospace, defense, transportation, automotive, energy, medical devices, and other industries that develop or operate safety-critical systems. Requirements vary by employer and may depend on the technologies, regulatory environment, and lifecycle stage involved.

Find System Safety Engineer Jobs on Ladders

Search Ladders for vetted professional opportunities with salaries of $100,000 or more. Review job requirements, compare roles, and find System Safety Engineer positions aligned with your experience and career goals.

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$134K - $205K *

Drive the commissioning process for power plants, ensuring peak performance and safety. Lead on-site activities, collaborate with teams, and implement protocols for mechanical equipment testing and op...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Technical Services

$145K - $205K *

Lead critical safety data exchange initiatives, ensuring compliance and high quality in pharmacovigilance partnerships. Collaborate with global partners to enhance operational governance and improve p...

Raleigh, NCRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $290K *

Oversee the design and evolution of global backbone architecture, driving initiatives in traffic engineering, capacity planning, and network automation. Collaborate with stakeholders to ensure strateg...

California, USRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$84K - $90K *

Optimize product development by collaborating with cross-disciplinary teams to enhance embedded systems, design software components, and ensure robust operation while addressing technical challenges i...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$90K - $150K *

Drive innovative electrical engineering solutions for renewable energy projects, focusing on design, analysis, and collaboration. Engage with diverse teams to enhance processes and ensure compliance w...

Pittsburgh, PARemote

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$77K - $115K *

Join a team that's dedicated to driving innovation by evaluating and implementing cutting-edge technologies and processes. Collaborate with diverse stakeholders to enhance business solutions through r...

Minneapolis, MNRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Join a team that's focused on optimizing biological treatment systems through innovative solutions. Collaborate closely with clients and internal experts, leveraging your technical expertise to enhanc...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Energy & Utilities

$120K - $150K *

Champion transformative AI adoption by working closely with enterprise clients, designing and executing integration solutions that elevate their operations and automate processes, while ensuring susta...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Join our team to deliver innovative waste management solutions. Collaborate with clients to optimize operations through tailored technology integrations and enhance sustainability efforts while drivin...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$150K - $180K *

The Security Program Manager will be responsible for securing OpenAI's critical product launches by coordinating security reviews and managing risks across cross-functional teams. This role ensures th...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Engineer cutting-edge AI evaluation strategies and infrastructure, ensuring quality and reliability across multi-tenant systems. Collaborate with senior teams to enhance product decisions through robu...

Georgia, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform enterprise AI deployments by designing, building, and enhancing systems that drive significant business results while fostering strong partnerships with customers and engineering teams...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Transform infrastructure by designing and building scalable GPU systems for AI cloud platforms, focusing on virtualization, Kubernetes, and automation to enhance performance and reliability across mul...

Bellevue, WARemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$220K - $290K *

Accelerate the development of autonomous systems by leading systems engineering strategies, aligning cross-functional teams, and ensuring rigorous safety and performance standards throughout the produ...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$120K - $170K *

Develop and enhance Python services for pharmacy claims processing. Collaborate across teams to deliver high-quality solutions while gaining expertise in the pharmacy benefits domain. Embrace a hybrid...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Drive the design and support of operational Active Network Management Systems, ensuring seamless integration and functionality throughout their lifecycle while collaborating with internal teams and cu...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$115K - $139K *

Lead the design and analysis of Nuclear Steam Supply System piping, ensuring compliance with ASME BPVC standards. Collaborate with cross-functional teams to develop technical specifications and innova...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$134K - $205K *

Lead the charge in ensuring quality standards for heavy industrial construction projects. Oversee QA/QC processes, conduct audits, and support contractors to enhance performance and safety throughout...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Technical Services

$130K - $160K *

Transform your career by leading a high-impact Developer Infrastructure team. Drive technical strategy, enhance developer experience, and foster a culture of growth and accountability while collaborat...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$121K - $208K *

Transform operational efficiencies by designing and deploying high-performance integration solutions. Collaborate with stakeholders to enhance user experiences and ensure data integrity across multi-t...

New York, NYRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $190K *

Lead the charge in defining and executing enterprise AI architecture strategy, ensuring scalable, ethical AI integration across platforms. Drive innovation through Generative and Agentic AI, aligning...

Florida, USRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$134K - $205K *

Join us in overseeing the commissioning of electrical systems in power plants. This leadership role involves managing fieldwork, strategic planning, and collaboration to ensure optimal performance and...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Technical Services

$105K - $189K *

Engineer innovative electrical designs, ensuring compliance and safety for mission-critical power and cooling products. Collaborate cross-functionally to integrate systems, manage changes, and execute...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$130K - $140K *

Advance your career by implementing and enhancing health and safety programs across the West Coast. Collaborate with leaders and teams to ensure compliance, conduct audits, and foster a culture of saf...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Help us deliver innovative environmental design projects by leading cross-functional teams through all phases from planning to implementation, ensuring alignment, managing risks, and achieving client...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What does a System Safety Engineer do?question toggle

    A System Safety Engineer identifies and evaluates hazards in complex systems, recommends ways to reduce risk, and collaborates with teams to incorporate safety into design, testing, and operations.

  • What qualifications are common for System Safety Engineer jobs?question toggle

    Employers commonly seek an engineering degree or related technical background, experience with safety or risk analysis, and familiarity with relevant industry standards. Specific requirements vary by role and sector.

  • Which industries hire System Safety Engineers?question toggle

    System Safety Engineers work in industries such as aerospace, defense, transportation, automotive, energy, and medical devices, as well as other fields involving safety-critical systems.

  • What skills are useful in a System Safety Engineer role?question toggle

    Useful skills include hazard identification, risk assessment, systems engineering, technical documentation, and communication. Experience with methods such as FMEA and fault tree analysis may also be valued.

  • Where can I find System Safety Engineer jobs paying $100,000 or more?question toggle

    Ladders features vetted professional job opportunities with salaries of $100,000 or more. Search the System Safety Engineer category to explore available roles and their requirements.