Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Staff Product Designer, Core
$195K - $237K *
Optimize the renter experience across digital platforms by leading design initiatives, balancing innovation with maintenance, and setting high standards for visual and interaction design. Collaborate...
3 weeks ago
Enterprise Solution Engineer - South East / Mid Atlantic
$110K - $130K *
Innovate at the forefront of data analytics by driving technical presales, engaging with customers, and delivering tailored solutions that enhance business agility and insights. Collaborate with cross...
2 weeks ago
$115K - $159K *
Elevate our global governance, risk, and compliance programme by leading risk assessments, policy governance, and audit support. Collaborate with cross-functional teams to ensure compliance with ISO 2...
6 days ago
Weapons Test & Evaluation Engineer (Associate, or Mid-Level)
$85K - $140K *
Join a team that's optimizing flight test operations for advanced weapon systems. Collaborate with industry leaders to ensure safety and efficiency while managing test procedures and configurations ac...
Reposted 2 days ago
Weapons Test & Evaluation Engineer (Associate, or Mid-Level)
$85K - $140K *
Join a team that's shaping the future of aerospace by leading flight tests and evaluations for advanced weapon systems. Collaborate with industry experts to ensure safety, quality, and efficiency in d...
3 days ago
$140K - $160K *
Design and enhance intelligent AI systems for K-12 assessment, collaborating across disciplines to create reliable, evaluative solutions that integrate seamlessly into educational frameworks and suppo...
Today
$140K - $160K *
Advance the design and implementation of a robust knowledge architecture for K-12 assessment systems, integrating AI and learning science to enhance educational outcomes through innovative, data-drive...
Today
Software Engineer || (Authentication)
$107K - $132K *
Join a team that's shaping the future of cloud services and authentication systems. As a key contributor, you'll design, build, and maintain scalable, secure solutions while collaborating with cross-f...
4 weeks ago
$90K - $100K *
Transform software delivery by managing cross-functional teams, aligning sprints, and optimizing project timelines. Drive clarity in processes and foster collaboration to ensure successful product exe...
Reposted 2 weeks ago
Senior Fire Protection Engineer
$95K - $115K *
Transform safety standards by leading fire protection system designs for diverse facilities. Collaborate with multidisciplinary teams to deliver innovative, compliant solutions that ensure reliability...
Reposted 2 weeks ago
$120K - $247K *
Unlock potential by leading complex digital production across diverse platforms, ensuring seamless execution of business and creative strategies. Collaborate with cross-functional teams to deliver imp...
Today
$86K - $112K *
Deliver innovative Salesforce solutions by leading design, development, and integration efforts. Collaborate with cross-functional teams to enhance operational efficiency and drive business value thro...
4 weeks ago
ServiceNow Senior Application Developer
$90K - $189K *
Drive the development and integration of enterprise applications on the ServiceNow platform, focusing on custom solutions and advanced scripting to enhance Configuration Management Database (CMDB) cap...
Today
Applications Engineers, Agentic Workflows
$110K - $130K *
Drive the future of engineering workflows by building and delivering robust AI-driven automation and agent-based capabilities, ensuring products meet real customer needs and are reliable for complex e...
Reposted today
Forward Deployed Engineer- AWS
$134K - $265K *
Engineer robust GenAI solutions by collaborating with clients and teams. Prototype high-impact AI applications while mentoring others and delivering measurable business outcomes using AWS AI capabilit...
Reposted 3 weeks ago
Platform Product Manager - Healthcare SaaS
$110K - $130K *
Empower cross-functional teams to innovate and enhance platform capabilities, ensuring alignment with client needs and regulatory standards. Drive product vision from inception to adoption, leveraging...
1 week ago
$108K - $154K *
Empower our innovative team as a Senior VDI Engineer, providing critical support for user-facing and data center services across multiple networks. Collaborate on design, implementation, and optimizat...
2 days ago
Senior Solutions Engineer, MSSP Partner
$196K - $270K *
Empower the growth of MSSP partnerships by driving adoption, building relationships, and integrating solutions. Collaborate with partners to enhance technical offerings and ensure success through trai...
2 weeks ago
Senior Power Systems Engineer, IBR Modeling, PSS/E and PSCAD
$130K - $157K *
Engineer innovative power system models and analyses to optimize utility-scale solar and storage solutions, working collaboratively with global teams to ensure compliance and advance SMA's technical c...
Reposted 5 days ago
Software Customer Service Manager
$100K - $115K *
Join a team that's dedicated to enhancing customer success through expert management of software solutions, ensuring exceptional service delivery and operational excellence in public safety environmen...
2 weeks ago
$139K - $174K *
Transform engineering projects by leading technical work and mentoring team members. Manage project scope, schedule, and resources while ensuring quality deliverables and compliance with industry stan...
Reposted 2 weeks ago
$77K - $95K *
Optimize cloud operations by managing and enhancing cloud compute systems. Collaborate with teams to ensure efficient capacity planning, alert monitoring, and customer support, while driving continuou...
Today
$160K - $175K *
Unlock potential by leading the design and implementation of scalable analytics solutions. Collaborate with stakeholders to enhance data-driven decision-making and mentor teams in analytics engineerin...
Today
Senior Director, Product Finance
$227K - $280K *
Lead strategic finance initiatives to empower product decisions, driving financial evaluations and business cases for new product lines. Collaborate with C-suite and product teams to optimize resource...
3 weeks ago
$80K - $95K *
Lead the charge in optimizing plant operations through data analysis, loss reduction, and employee training. Drive continuous improvement initiatives to enhance performance metrics and foster a cultur...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.