Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$125K - $150K *
Elevate your career as a Senior Data Engineer, driving innovation in cloud-native data pipelines and architectures. Leverage your expertise in structured credit and financial analytics to modernize da...
2 weeks ago
Staff Electrical Engineer - Substation (Kansas City)
$95K - $115K *
Shape the future of high-voltage substation projects by developing design deliverables, collaborating with project teams, and ensuring quality standards are met throughout the engineering process. Joi...
1 week ago
$95K - $115K *
Champion project delivery by overseeing HV cable testing projects across North America. Ensure alignment with client expectations while managing resources, schedules, and budgets for successful comple...
Reposted 1 week ago
$105K - $202K *
Innovate and build AI-native products that automate complex workflows. Collaborate with cross-functional teams to design, develop, and deploy full-stack applications, ensuring reliability and performa...
3 weeks ago
$146K - $225K *
Transform vendor performance and customer satisfaction by leading strategic initiatives across a global BPO network. Drive accountability, analyze data, and collaborate cross-functionally to enhance o...
2 weeks ago
Account Executive - Attribute™, North America
$110K - $130K *
Accelerate growth by building a new region from scratch, driving sales, and establishing customer success stories for a groundbreaking FinOps solution. Own the full sales cycle, focusing on net-new lo...
Today
Product Engineer II - Utility Solutions
$79K - $133K *
Drive the design and development of geospatial solutions for utilities, enhancing operations and services across multiple industries, including electric, gas, and telecommunications, while collaborati...
Reposted today
$110K - $130K *
Transform the member experience by owning the full lifecycle of features across a cutting-edge AI-first platform, leveraging technologies from React to GraphQL and AI services to deliver personalized...
5 days ago
Senior Associate, Full Stack AI Engineer — AWS
$77K - $202K *
Bring your expertise to design and develop cloud-native applications using AWS. As a Senior Associate, you'll tackle complex problems, mentor junior staff, and enhance client relationships while drivi...
2 weeks ago
$97K - $126K *
Transform marketing strategies by connecting buyer needs with sales execution. Lead integrated campaigns, enhance customer engagement, and drive growth through innovative go-to-market planning and col...
3 weeks ago
Solution Advisory Senior Manager - Enterprise Performance & Productivity
$132K - $338K *
Shape enterprise performance by leading strategic initiatives that drive productivity and cost transformation. Collaborate with senior stakeholders to develop tailored solutions that enhance client va...
1 week ago
Senior Revenue Operations Program Manager
$145K - $160K *
Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...
4 weeks ago
Staff Product Manager, Databases
$243K - $304K *
Transform the future of data integration by leading product strategy for our database connectors. Collaborate with engineering and sales teams to drive impactful product decisions that enhance analyti...
Today
$160K - $180K *
Transform digital healthcare services by designing and deploying scalable machine learning models. Collaborate with cross-functional teams to enhance predictive capabilities and ensure compliance with...
6 days ago
$131K - $237K *
Join a dynamic team to develop innovative software solutions for aeronautical navigation. Leverage your coding skills in a collaborative Agile environment, integrating open-source technologies and enh...
1 week ago
$107K - $195K *
Join a team that's shaping the future of aeronautical navigation through innovative software solutions. Collaborate in an Agile environment to enhance existing systems and develop new functionalities...
1 week ago
Sr. Practice Manager -- Data Platforms
$150K - $190K *
Lead the charge in shaping data platform strategies and governance, driving innovative solutions and team development. Collaborate with partners to enhance AI readiness and ensure successful technical...
2 weeks ago
$95K - $115K *
Advance your career by leading complex projects that drive strategic goals. Collaborate with cross-functional teams to ensure timely delivery, compliance, and risk management while enhancing business...
3 weeks ago
$100K - $120K *
Lead the charge in managing complex projects that drive strategic goals. Oversee project lifecycles, ensuring timely delivery, compliance, and stakeholder engagement while fostering collaboration acro...
3 weeks ago
Staff Product Manager, AI Applications
$150K - $180K *
Take ownership of the product strategy for AI applications, defining the roadmap and driving profitability. Collaborate cross-functionally to build and launch innovative products that enhance user exp...
3 weeks ago
Remote Sensing / Signal Processing Software Engineer
$135K - $145K *
Lead the development of advanced geospatial systems by integrating software, algorithms, and data processing for remote sensing and signal processing applications, ensuring seamless interaction across...
2 weeks ago
Senior Staff Product Designer, Core
$195K - $237K *
Optimize the renter experience across digital platforms by leading design initiatives, balancing innovation with maintenance, and setting high standards for visual and interaction design. Collaborate...
3 weeks ago
Enterprise Solution Engineer - South East / Mid Atlantic
$110K - $130K *
Innovate at the forefront of data analytics by driving technical presales, engaging with customers, and delivering tailored solutions that enhance business agility and insights. Collaborate with cross...
2 weeks ago
$115K - $159K *
Elevate our global governance, risk, and compliance programme by leading risk assessments, policy governance, and audit support. Collaborate with cross-functional teams to ensure compliance with ISO 2...
6 days ago
Weapons Test & Evaluation Engineer (Associate, or Mid-Level)
$85K - $140K *
Join a team that's optimizing flight test operations for advanced weapon systems. Collaborate with industry leaders to ensure safety and efficiency while managing test procedures and configurations ac...
Reposted 2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.