Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sr. Engineer - Platform Data Engineer (Remote)
$140K - $215K *
Unlock potential by architecting and managing robust data infrastructure, ensuring reliability and scalability while mentoring junior engineers and enhancing platform performance in a dynamic analytic...
1 week ago
$100K - $120K *
Join a team that's advancing national security by securing our infrastructure. Work collaboratively in a dynamic environment to enhance IT engineering efforts, ensuring compliance and safeguarding cru...
Reposted yesterday
Sr. Product Manager, AI & Data
$130K - $155K *
Shape the future of data and AI solutions by driving product success, collaborating with cross-functional teams to align business goals with innovative platforms and ensuring continuous improvement th...
1 week ago
Plant Process Simulation Engineer II
$115K - $150K *
Join a team that's dedicated to advancing clean energy by developing and owning plant process simulation models. Collaborate across disciplines to enhance design, operations, and plant dynamics for in...
1 week ago
Senior Expert Engineer Industrial Services
$149K - $205K *
Contribute to engineering compliance by leading audits and assessments across North American factories. Drive standardization, mitigate risks, and enhance regulatory adherence while collaborating with...
1 week ago
$130K - $163K *
Shape the future of AI in our organization as a strategic leader driving enterprise-wide adoption and integration of AI technologies, enhancing productivity and delivering measurable results through i...
Reposted 4 weeks ago
Manager-Software Engineering (Remote)
$112K - $140K *
Reimagine the future of software engineering by leading a dynamic team to develop and maintain innovative web applications. Drive collaboration, enhance product quality, and ensure successful project...
4 weeks ago
Product Manager, Ignite Member Operations
$125K - $141K *
Lead the product direction for membership operations, balancing customer needs and enterprise requirements. Collaborate with teams to enhance workflows, improve operational outcomes, and ensure a seam...
6 days ago
Senior Product Manager, Shared Hosting
$140K - $170K *
Join us to redefine the customer journey for our shared hosting platform, focusing on retention and user experience. You'll lead strategy and execution, ensuring customers thrive post-purchase and enh...
2 weeks ago
Customer Onboarding Operations Manager
$100K - $120K *
Transform customer activation by leading operational readiness and training coordination. Manage a team to streamline onboarding processes and enhance productivity, ensuring customers reach their init...
Reposted 1 week ago
$90K - $113K *
Help us drive IT excellence by managing a diverse portfolio of technology projects, ensuring alignment with strategic goals, and fostering collaboration across teams to deliver impactful results in a...
2 weeks ago
Chief of Staff, Digital & Product
$161K - $242K *
Join a team that's driving strategic initiatives and digital transformation. Collaborate with senior leaders to tackle complex challenges, influence decision-making, and ensure successful execution of...
Reposted yesterday
Senior Partner Sales Manager - Databricks
$150K - $180K *
Lead transformative sales initiatives by cultivating strategic partnerships, driving growth and delivering revenue through new-logo acquisition while managing enterprise-level client relationships for...
Reposted 4 days ago
Lead Forward Deployed Engineer - Databricks
$189K - $372K *
Empower innovation by driving GenAI solutions with strategic clients. Lead and mentor engineering teams, streamline delivery processes, and ensure high-quality outcomes while aligning business goals w...
Reposted 3 weeks ago
Lead Forward Deployed Engineer - Databricks
$189K - $372K *
Champion the development and deployment of GenAI solutions, leading engineering pods to drive innovation in strategic client engagements, influencing at the executive level while overseeing both onsho...
Reposted 3 weeks ago
Senior Business Development Manager
$110K - $130K *
Join a team that's driving growth by sourcing and closing new business while nurturing existing accounts. You'll be the trusted operator ensuring client satisfaction and pipeline predictability, colla...
3 weeks ago
Project Manager, Industrial Controls Implementation
$116K - $170K *
Join a dynamic team to drive the planning and execution of PLC updates, ensuring seamless operations across automated warehouse sites while coordinating with cross-functional partners and enhancing de...
Reposted 4 days ago
$150K - $170K *
Unlock potential by leading hands-on security engineering efforts to modernize cybersecurity for a major federal agency. Collaborate with teams to remediate vulnerabilities and enhance cloud infrastru...
Today
Senior Manager, Lifecycle Marketing
$181K - $245K *
Elevate your career by leading lifecycle marketing strategies that enhance customer engagement, retention, and monetization. Drive impactful programs while managing a high-performing team and collabor...
1 week ago
$110K - $130K *
Take ownership of IT infrastructure and security operations, driving the migration to a Nutanix-based IaaS environment. Collaborate with teams to enhance security, compliance, and automation, utilizin...
4 weeks ago
Senior Lead Customer Success Manager
$137K - $235K *
Elevate customer success by managing strategic enterprise relationships, driving platform adoption, and mentoring teams. Collaborate with C-suite stakeholders to ensure impactful outcomes and contribu...
6 days ago
$77K - $147K *
Join a dynamic team as a Senior CX Manager, driving strategic customer success through technical enablement and relationship management. Leverage your expertise to lead complex initiatives and foster...
4 days ago
$163K - $224K *
Join a team that's redefining People Operations by leading global service delivery, enhancing employee experiences, and driving operational excellence across Talent Acquisition and People processes fo...
Reposted 2 weeks ago
Senior Manager, ServiceNow HRSD Program and Solution Management
$171K - $338K *
Lead transformative HRSD initiatives by managing client relationships, optimizing ServiceNow solutions, and mentoring teams. Drive strategic growth through innovative AI integration and ensure high-qu...
2 weeks ago
Senior Manager, ServiceNow HRSD Program and Solution Management
$171K - $338K *
Unlock potential by leading ServiceNow HRSD engagements, driving strategy, and advising clients on AI integration. Manage teams and relationships to enhance HR and IT service delivery across diverse i...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.