Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$179K - $204K *

Drive innovation by architecting and building scalable greenfield products, collaborating with cross-functional teams to transform consumer needs into impactful features while mentoring fellow enginee...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$88K - $214K *

Shape enterprise data architectures by leveraging your expertise in Databricks and modern cloud platforms. Collaborate with clients to design scalable solutions that drive analytics, AI/ML, and data g...

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $135K *

Transform the insurance landscape by leading product innovation and development initiatives, enhancing personal Property products to meet member needs and drive profitable growth while ensuring market...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $150K *

Advance your career by leading product strategy for supply chain orchestration. Drive technical decisions, collaborate with cross-functional teams, and leverage AI to enhance workflows, ensuring measu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$115K - $169K *

Drive successful project execution by managing capital projects from concept to completion, ensuring adherence to design, scope, and milestones while coordinating with clients and teams for optimal re...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$120K - $145K *

Help us drive technical strategy and solutions for enterprise clients, addressing security challenges and delivering impactful demonstrations. Collaborate with cross-functional teams to translate comp...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$260K - $300K *

Advance your career by driving new business growth through consultative sales. Leverage your technical expertise to engage customers, manage sales processes, and foster strong relationships, ensuring...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$132K - $165K *

Shape the future of billing and collections by driving product strategy and enhancing user experiences. Collaborate with cross-functional teams to deliver reliable payment solutions that boost revenue...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$117K - $129K *

Lead the charge in optimizing operational performance for solar energy projects. Collaborate with engineers to analyze performance data, develop solutions, and ensure project success, while fostering...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$150K - $180K *

Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$138K - $185K *

Transform your career by leading enterprise data and AI architecture initiatives. Collaborate with cross-functional teams to drive technology adoption and ensure alignment with business needs while in...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$125K *

Transform the future of mobile development by leveraging AI to enhance marketplace experiences. Collaborate with cross-functional teams to design, build, and ship high-quality Android applications tha...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$73K - $212K *

Lead innovative AI solutions as a Manager in Data and Analytics Engineering. Supervise teams, manage client accounts, and drive exceptional results while fostering relationships and embracing technolo...

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$148K - $185K *

Join us to create user-centered designs that enhance account opening experiences for banks and credit unions, collaborating closely across teams to innovate and uphold a high standard of quality and c...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K *

Drive the future of project controls by providing expert EVM, cost, and schedule analysis for federal programs. Collaborate with cross-functional teams to enhance decision-making and ensure program co...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$160K - $200K *

Architect innovative solutions as a Senior Solutions Engineer, driving technical excellence in public sector engagements. Collaborate with clients to demonstrate product value, lead RFP responses, and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$184K - $200K *

Unlock potential by driving the vision and strategy for innovative products that empower independent candidates and enhance user engagement. Collaborate with cross-functional teams to create scalable...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Business Services

$160K - $220K *

Champion the design and architecture of data systems, driving innovation and collaboration across teams to enhance user experiences and optimize data management for MyFitnessPal's ecosystem...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Shape the future of homebuilding by leading a small team of engineers to develop innovative solutions. Balance technical ownership and people leadership while driving impactful projects from concept t...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in enhancing cloud security by conducting proactive reviews, managing complex incidents, and collaborating with cross-functional teams to improve detection and response mechanisms whil...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Advance your career by owning corporate FP&A, driving financial insights, and partnering with leaders across functions to enhance strategic planning and reporting in a dynamic growth-stage environment...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $149K *

Lead the charge in delivering complex product development projects by managing cross-functional teams, ensuring customer satisfaction, and driving operational excellence from initiation to delivery in...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$181K - $214K *

Lead the charge in defining and executing on-platform measurement strategies, ensuring effective ad performance tracking and reporting across diverse ad formats while collaborating with engineering an...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Technical Services

$205K - $285K *

Grow your career with a dynamic team managing data center operations. Lead technical teams in hardware installation, configuration, and troubleshooting while driving safety initiatives and optimizing...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $210K *

Lead the charge in transforming people analytics by applying causal inference and advanced statistical methods to drive strategic decisions on recruitment, retention, and compensation across the organ...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.