Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$80K - $95K *
Engineer automated systems to enhance production efficiency and quality. Lead projects from design to implementation, optimizing processes through data analysis and collaboration with cross-functional...
2 weeks ago
$360K - $495K *
Lead the charge in product management, driving strategy and execution across multiple product pillars. Build a high-performing team, establish operational excellence, and ensure customer-centric outco...
1 week ago
Staff Product Security Engineer
$150K - $180K *
Champion the security strategy for a cutting-edge platform, focusing on supply chain security, code scanning, and threat modeling. Collaborate with teams to enhance security practices and drive innova...
2 weeks ago
Mid-Level Supplier Quality Engineer - Technical Integration
$100K - $135K *
Analyze supplier capabilities and integrate quality into engineering processes. Contribute to continuous improvement initiatives, ensuring compliance with specifications and regulations while fosterin...
Reposted yesterday
Mid-Level Supplier Quality Engineer - Technical Integration
$100K - $135K *
Drive supplier quality assurance by integrating engineering processes, assessing capabilities, and mitigating risks. Collaborate cross-functionally to enhance supplier performance and ensure complianc...
Reposted 2 days ago
Application Deployment Engineer
$100K - $120K *
Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...
Reposted today
$84K - $87K *
Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...
Reposted 3 weeks ago
Senior Mobile Software Engineer - Android & iOS
$135K - $160K *
Grow your career with a dynamic frontend engineering team focused on building robust platforms. Collaborate across teams to enhance product features, ensure high-quality deliverables, and drive innova...
2 weeks ago
Digital Employee Experience Senior Engineer, IT Client Services
$89K - $139K *
Drive the transformation of employee experiences by leading a multi-year Digital Employee Experience (DEX) program. Oversee analytics, enhance productivity, and implement AI-driven solutions to optimi...
6 days ago
Senior Strategic Program Manager, Data Center and AI
$132K - $165K *
Accelerate progress at multi-site data center and AI programs valued over $25M. Lead diverse teams to ensure successful delivery, budget management, and customer satisfaction while driving executive c...
3 weeks ago
$120K - $170K *
Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...
1 week ago
Software Engineer - ML Ops (R37)
$140K - $270K *
Unlock your potential by managing ML systems at scale, ensuring uptime and observability. Collaborate on deploying and scaling models, while enhancing platform reliability through advanced engineering...
3 weeks ago
Infrastructure Solutions Engineer
$136K - $170K *
Drive impactful infrastructure solutions by collaborating with engineering teams to resolve blockers, execute migrations, and develop tooling. Leverage your expertise to enhance platform adoption and...
2 weeks ago
$80K - $95K *
Innovate software solutions by designing, developing, and maintaining applications throughout their lifecycle, ensuring adherence to best practices and architectural standards while collaborating with...
Yesterday
$80K - $95K *
Join a team that's dedicated to crafting innovative software solutions. You'll design, develop, and maintain applications while collaborating with peers to ensure best practices and adherence to archi...
1 week ago
$110K - $130K *
Join a team that's redefining product management by building innovative features from concept to launch. Leverage AI tools to enhance efficiency and drive product operations, ensuring seamless deliver...
1 week ago
$95K - $115K *
Unlock your potential as a Senior VDC Engineer, driving innovative design solutions and enhancing project delivery through advanced BIM technologies and collaboration with diverse teams in a dynamic e...
2 weeks ago
$105K - $150K *
Transform your career by joining a dynamic team focused on enhancing security compliance for cloud services. Leverage your expertise in IT security to assess architectures, guide vendors, and ensure a...
5 days ago
$100K - $120K *
Drive the development and integration of advanced nuclear energy systems by applying systems engineering methods to translate objectives into clear, verifiable requirements and solutions, while collab...
1 week ago
$190K - $220K *
Partner with us to tackle complex engineering challenges, leveraging deep expertise in TypeScript, Postgres, and AWS. Collaborate closely with our VP of Engineering to innovate and deliver impactful p...
Reposted today
$116K - $171K *
Elevate customer success by partnering with developers to implement solutions, troubleshoot technical issues, and enhance product features. Your insights will drive improvements across teams, ensuring...
3 weeks ago
$95K - $159K *
Elevate your career by ensuring software quality and compliance in innovative cloud and AI/ML systems, collaborating with cross-functional teams to enhance product development and uphold stringent saf...
Reposted 3 weeks ago
Software Architect (AWS/Azure)
$101K - $135K *
Join a team that's shaping the future of healthcare technology by designing and enhancing our build and delivery infrastructure. Collaborate with architects and developers to implement best practices...
2 weeks ago
Sr. Manager, Solutions Architect - SMB
$135K - $160K *
Transform customer engagement by leading a team of Solutions Architects, driving technical strategy and operational excellence across the India region while ensuring alignment with cross-functional pa...
1 week ago
Technical Product Manager, Core Banking
$120K - $145K *
Lead the charge in transforming our core banking platform by driving technical architecture and integration. Collaborate with cross-functional teams to deliver scalable solutions that enhance operatio...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.