Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Principal Product Manager, Agentic AI
$280K - $300K *
Pioneer innovative AI solutions in workforce management, leading product development from concept to deployment. Collaborate with engineers and executives to create impactful agentic products that enh...
2 weeks ago
Director, Engineering, Platform/Services
$216K - $318K *
Drive innovation as you lead engineering teams to build and scale Life360's critical platforms. Ensure reliability and security while fostering a culture of accountability and technical excellence for...
2 weeks ago
Principal Consulting Engineer - VMware Cloud Foundation Operations
$164K - $240K *
Accelerate progress at the forefront of private cloud architecture by designing, deploying, and optimizing solutions. Leverage your expertise to drive standards, mentor teams, and cultivate robust cli...
Reposted 3 days ago
Software Engineer – AI Applications & ServiceNow
$100K - $130K *
Drive the design and deployment of secure AI applications in cloud environments, integrating advanced technologies like machine learning and ServiceNow solutions to enhance operational efficiency and...
1 week ago
Senior Full-Stack Cloud Developer
$102K - $170K *
Lead the charge in full-stack development, collaborating on enterprise modernization with Microservices. Deliver high-quality software, mentor engineers, and ensure best practices for cloud technologi...
Reposted 3 weeks ago
Senior Program Manager, Contingent Workforce
$107K - $180K *
Drive the strategy and operations of a dynamic contingent workforce program, enhancing governance and service delivery. Collaborate cross-functionally to implement scalable processes and support inter...
5 days ago
Software Engineer II (Infor LN)
$95K - $115K *
Elevate your career by developing innovative solutions within the Infor LN platform. Collaborate with cross-functional teams to enhance payment processing capabilities and create seamless integrations...
1 week ago
$104K - $140K *
Help us drive innovation as a Principal Electrical Engineer, specializing in power systems. You will lead design teams, engage with customers, and develop cutting-edge power electronics to meet requir...
Reposted 3 days ago
$140K - $160K *
Architect robust Azure cloud solutions while ensuring system performance, security, and scalability. This hands-on role requires deep technical expertise, collaboration with cross-functional teams, an...
Reposted 4 weeks ago
$127K - $163K *
Empower the design and delivery of scalable data solutions on Google Cloud, leading a team to enhance operational excellence and drive strategic business outcomes through innovative data engineering p...
1 week ago
Senior Associate, Operational Intelligence, Labs
$93K - $138K *
Join a team that's dedicated to enhancing operational efficiency through innovative software solutions. As a key contributor, you'll develop and maintain applications that streamline processes, ensuri...
6 days ago
Senior Manager, Solutions Engineering - Commercial, Site Security
$215K - $270K *
Lead the charge in building a high-performing Solutions Engineering team focused on autonomous site security. Drive technical sales, manage customer engagements, and ensure consistent quota attainment...
4 weeks ago
Senior Strategic Program Lead, GFCO
$130K - $154K *
Shape the future of financial crimes compliance by leading complex programs that enhance operational efficiency and regulatory adherence. Collaborate with cross-functional teams to drive strategic ini...
3 weeks ago
Full Stack Software Engineer | Las Vegas, NV| Remote
$115K - $120K *
Support software design and coding in a collaborative environment, enhancing internal systems and resolving bugs while continuously developing coding skills in a diverse technology landscape...
Reposted today
Full Stack Software Engineer | Las Vegas, NV| Remote
$115K - $120K *
Lead the charge in software design and development, enhancing internal systems with innovative coding solutions while collaborating within a dynamic team environment focused on quality and efficiency...
Reposted today
Site Reliability Engineering Manager
$114K - $190K *
Build a resilient Site Reliability Engineering practice, leading a global team to enhance cloud platform reliability, scalability, and operational excellence while fostering collaboration and continuo...
2 weeks ago
Senior Supervising Process Engineer
$125K - $225K *
Drive innovation and strategic leadership in wastewater treatment and reuse projects, guiding multidisciplinary teams to deliver sustainable, cutting-edge engineering solutions while fostering client...
Reposted today
Senior Product Manager, Ting Consumer Products
$110K - $130K *
Shape innovative consumer experiences as a Product Manager, driving strategy, roadmap, and customer insights. Collaborate with marketing and engineering to expand distribution and elevate web and mobi...
Reposted today
$110K - $130K *
Elevate data engineering capabilities by designing robust ETL/ELT workflows, ensuring data quality, and implementing scalable solutions on AWS and Kubernetes. Collaborate with teams to optimize perfor...
3 weeks ago
Sr Product Manager, Large Ag Autonomy
$142K - $250K *
Accelerate innovation in autonomous agriculture by leading product strategy, collaborating with engineering and commercial teams, and transforming customer insights into impactful solutions that drive...
5 days ago
$104K - $140K *
Take ownership of engineering projects, ensuring timely and budget-compliant delivery while leading cross-functional teams and liaising with various departments to meet customer specifications...
Reposted 1 week ago
$122K - $150K *
Support the design and maintenance of a global virtual desktop environment, serving as the SME for troubleshooting and optimizing performance while collaborating across multiple complex production env...
1 week ago
Senior Manager, Business Development
$125K - $150K *
Lead the charge in driving new business acquisition and expanding opportunities across Consumer Goods, Retail, and Travel sectors. Leverage industry expertise to build relationships and position as a...
5 days ago
Professional Services Operations Lead
$88K - $105K *
Drive operational excellence by owning the Professional Services intake and workflow governance processes, ensuring efficient request management and seamless team collaboration to enhance service deli...
1 week ago
Staff Backend Engineer - Infrastructure Access - US
$135K - $160K *
Transform the Teleport Core Product by tackling performance, scalability, and security challenges. Lead a distributed team to design, develop, and implement high-quality solutions while enhancing obse...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.