Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$180K - $229K *
Join a team that's shaping the future of insurance technology by leading engineering efforts, collaborating with cross-functional teams, and driving strategic initiatives to enhance product effectiven...
2 weeks ago
Senior Software Engineer, Backend
$135K - $187K *
Grow your career with a dynamic team focused on crafting scalable software solutions. Collaborate cross-functionally to design impactful APIs and lead innovations that drive efficiency and elevate cus...
Reposted 2 days ago
Staff Software Engineer - Files Platform
$158K - $248K *
Unlock potential by architecting scalable file management solutions, integrating distributed systems, and ensuring secure access for enterprise customers. Collaborate across teams to enhance data acce...
Reposted today
Staff Software Engineer, Enterprise
$193K - $309K *
Innovate by leading the development of scalable features for our Sports & Entertainment platform. Collaborate across teams to enhance customer experiences and drive Toast's success while mentoring fel...
Reposted 4 days ago
$168K - $210K *
Lead the transformation of our build and deploy systems while enhancing developer efficiency, safety, and software delivery reliability. Collaborate across teams to drive technical innovation and opti...
Reposted 4 days ago
Staff Software Engineer, Platform
$135K - $160K *
Transform the core platform of a 1-1 coaching marketplace by co-owning its architecture, enhancing scalability, and driving technical direction. Collaborate with teams to ensure reliability and effici...
Yesterday
Staff Software Engineer, Cloud Infrastructure
$212K - $265K *
Elevate your career by developing cutting-edge cloud infrastructure that powers seamless operations across teams. Collaborate with talented engineers to enhance reliability, scalability, and efficienc...
Reposted 2 weeks ago
Staff Software Engineer, On-Prem
$205K - $285K *
Transform the on-premises CI/CD landscape by enhancing reliability, simplifying installations, and driving technical strategy. Collaborate with teams to build tools that empower engineers and ensure s...
2 weeks ago
Senior Manager, Software Engineering
$225K - $265K *
Partner with us to lead a high-performing engineering team, driving innovation and efficiency in our travel marketplace. You'll manage project lifecycles, enhance collaboration, and champion a custome...
2 weeks ago
Staff Software Engineer, Developer Experience
$193K - $309K *
Pioneer innovative developer experiences by setting technical direction and enhancing workflows. Collaborate across teams to design solutions that empower engineers, leveraging AI to redefine software...
Reposted 4 days ago
Staff Software Engineer, Partner Integrations
$229K - $260K *
Transform the integration landscape by architecting robust connections between NodeZero and key security platforms, ensuring reliability and observability while mentoring engineers and driving technic...
1 week ago
Staff Software Engineer, Public Sector
$188K - $272K *
Transform the future of federal technology by leading software engineering efforts that develop advanced systems for real-time decision-making and agentic capabilities across multiple domains, while m...
Reposted 4 days ago
$150K - $180K *
Unlock potential by leading technical vision and mentoring engineers. Drive modernization and collaboration across teams to build resilient, scalable infrastructure while fostering a high-performance...
5 days ago
$169K - $185K *
Champion the design and delivery of integrations and APIs, collaborating with cross-functional teams to create secure, scalable, and user-friendly developer experiences that drive business impact and...
1 week ago
Staff Software Engineer - Data
$198K - $297K *
Join us to lead the design and evolution of a cutting-edge Real-Time Analytics Platform, driving high-throughput, low-latency data solutions. Collaborate with cross-functional teams to enhance scalabi...
2 weeks ago
Staff Software Engineer, Consumer 360
$154K - $227K *
Join a dynamic team as a technical leader, driving scalable software solutions and mentoring engineers. Collaborate across teams to enhance engineering practices and deliver innovative AI-driven appli...
1 week ago
Staff Software Engineer- AI Platform
$150K - $180K *
Develop and manage scalable AI infrastructure solutions, ensuring secure access to foundation models. Collaborate with cross-functional teams to enhance platform capabilities and drive AI adoption whi...
1 week ago
Staff Software Engineer - Fintech
$225K - $325K *
Elevate your career by driving innovation in FinTech. As a key engineer, you'll shape the future of revenue management systems, ensuring accuracy and reliability while collaborating across teams to op...
4 weeks ago
Sr. Staff Software Engineer, Cribl AI
$250K - $300K *
Shape the future of observability data by integrating cutting-edge AI into core products. Collaborate with engineers to solve real customer challenges while innovating and refining user experiences ac...
Reposted today
Staff Software Engineer - Cloud Services
$145K - $175K *
Pioneer innovative cloud architectures and drive scalable solutions for a cloud-native platform. Collaborate with engineering leaders to enhance reliability, security, and performance while mentoring...
Today
$120K - $130K *
Elevate your career by leading the design and implementation of complex software solutions. Collaborate with cross-functional teams to drive technical decisions and mentor engineers, ensuring scalable...
Reposted today
$120K - $130K *
Drive the design and implementation of complex software solutions, providing technical leadership and mentorship. Collaborate with cross-functional teams to enhance system architecture and ensure high...
6 days ago
Staff Software Engineer (Insurance Tech)
$245K - $270K *
Shape the future as a hands-on engineer, architecting systems and driving best practices while crafting innovative solutions that leverage AI to enhance customer value and modernize legacy platforms...
Reposted 2 days ago
Senior Software Development Engineer
$156K - $262K *
Drive innovation by architecting and developing full stack web applications, mentoring engineers, and ensuring high-quality solutions that enhance user experiences and operational efficiency across di...
Today
Staff Software Engineer, Tech Lead - NetBox Delivery
$135K - $160K *
Unlock the potential of NetBox Delivery by leading software design, enhancing production reliability, and mentoring engineers. Shape the technical direction and ensure seamless deployment on Cloud and...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.