Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $150K *

Transform your career by owning complex software features that integrate virtual machines into a secure platform. Collaborate across teams to deliver innovative solutions while establishing strong eng...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Innovate with us as a Senior Software Engineer, driving core feature development and automation across the stack. Collaborate with diverse teams to enhance scalability and performance in a dynamic, mi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $267K *

Champion innovation by leading cross-functional teams to design and deliver scalable, high-performance infrastructure solutions that enhance reliability and efficiency across diverse applications and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$230K - $260K *

Lead the charge in client migrations, owning the entire technical lifecycle from legacy analysis to deployment, ensuring precision and collaboration across teams for optimal outcomes...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Lead and grow a high-performing platform engineering team, setting vision and roadmap while collaborating with cross-functional leaders to enhance product velocity and reliability for enterprise custo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$145K - $200K *

Transform your career by developing robust SDKs that empower customers globally. Collaborate with cross-functional teams to enhance performance and resiliency while contributing to open-source project...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $200K *

Transform backend services and REST APIs in a collaborative environment. Leverage your software engineering skills to support cyber training initiatives, utilizing modern technologies and cloud infras...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$173K - $233K *

Unlock innovative solutions as you collaborate across teams to enhance user experiences on mobile and web platforms. Drive impactful projects, support product development, and contribute to a thriving...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $220K *

Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$140K - $190K *

Innovate software solutions in dynamic environments, collaborating with operators and engineers to rapidly prototype and deploy mission-critical capabilities. Leverage your technical expertise to inte...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$130K - $140K *

Contribute to the development of a modern platform by building features, connecting systems, and improving data usability. Engage with stakeholders and troubleshoot to deliver reliable software as par...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Staffing

$466K - $500K+*

Unlock potential by developing scalable AI/ML model serving infrastructure. Collaborate cross-functionally to enhance performance and availability of high-traffic systems, driving innovation in a dyna...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$230K - $290K *

Join a team that's dedicated to enhancing account security through innovative solutions. You'll lead technical strategies, collaborate across teams, and foster a culture of quality while ensuring seam...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$144K - $220K *

Drive technical excellence as a Senior Staff Engineer, leading the Ops Portal team in shaping architecture and product direction across multiple platforms, while ensuring robust, scalable solutions fo...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Champion innovation as a Senior Software Engineer, driving full-stack solutions and leveraging AI tools to enhance IT lifecycle management. Collaborate with a dynamic team to deliver impactful softwar...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Empower our Digital team as a Senior Software Engineer, driving full stack development and modernization initiatives. Collaborate closely to enhance our Digital Banking platform, architecting new APIs...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $200K *

Advance backend solutions and frontend features, collaborating across teams to build scalable systems and AI integrations, driving product growth from conception to execution...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$115K - $194K *

Engage with the developer community as you advocate for our platform, creating compelling content, conducting demos, and gathering feedback to enhance product features, all while building relationship...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $250K *

Elevate the search experience by designing and evolving a robust backend system that powers millions of searches. Collaborate across teams to enhance scalability, reliability, and maintainability whil...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$218K - $256K *

Empower our engineering teams by owning core developer infrastructure tools and systems. Drive strategic initiatives, enhance CI/build processes, and ensure reliability while mentoring engineers and s...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $160K *

Lead the charge in solving critical engineering challenges, driving technical direction, and fostering team growth. Collaborate across departments to enhance systems, ensuring reliability and innovati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$157K - $184K *

Engineer and elevate our core product by developing innovative features, tools, and infrastructure while collaborating closely with a dedicated team to maintain high-quality standards and drive techni...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$86K - $165K *

Join a team that's redefining cloud deployment by leveraging cutting-edge technologies. You'll design and implement scalable solutions, mentor peers, and enhance DevSecOps pipelines, all while collabo...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$165K - $225K *

Elevate infrastructure capabilities by designing and implementing a unified platform that integrates bare-metal servers, storage, and networking for large-scale computation and AI workloads, ensuring...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$199K - $274K *

Transform enterprise-scale engineering capabilities by leading the TORC function, fostering collaboration across security and operations, and delivering innovative solutions for risk and control manag...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.