Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$200K - $220K *

Lead product management for an innovative infrastructure automation platform, driving strategy and vision while managing a team of senior product managers. Collaborate cross-functionally to enhance cu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $130K *

Transform your career by leading automation projects that enhance manufacturing efficiency. Collaborate with cross-functional teams to implement innovative solutions while ensuring safety and complian...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$125K - $150K *

Transform enterprise data architecture through expert Azure platform engineering, enhancing reliability, governance, and cost-efficiency while collaborating with cross-functional teams to optimize dat...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Shape the future of product management by leading complex engagements, defining vision, and ensuring seamless collaboration across teams to deliver exceptional results and drive product success...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $160K *

Lead the charge in advancing next-gen GPS and PNT systems through architecture, requirements development, and project management, ensuring compliance and collaboration across engineering teams for mis...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$104K - $155K *

Lead the charge in customer-focused project management, ensuring effective delivery of technical solutions while coordinating with diverse stakeholders and fostering strong relationships for successfu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$76K - $158K *

Elevate your career by leading the administration and optimization of IBM Z-Series mainframe systems. Drive core business operations through technical expertise, mentoring, and continuous improvement...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Engage with cross-functional teams to drive AI security product marketing initiatives, focusing on buyer insights, competitive analysis, and effective sales enablement. Collaborate on launches and con...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$96K - $181K *

Lead the transformation of enterprise technology by architecting scalable GCP solutions and guiding cross-functional teams in developing robust AI-driven applications. Drive innovation through hands-o...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$123K - $185K *

Lead the charge in optimizing process control and equipment projects across multiple manufacturing plants, driving improvements and ensuring effective implementation in the Feed Manufacturing Operatio...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$130K - $155K *

Lead the charge in developing Fleetio's connected-vehicle data strategy and product line from the ground up. Drive innovative data solutions, partnerships, and user experiences that enhance fleet oper...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$193K - $228K *

Join a dynamic team to lead complex, cross-functional programs, ensuring timely delivery of high-quality features while driving alignment across Product, Engineering, and Design teams in a fast-paced...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$88K - $105K *

Advance your career by enhancing manufacturing efficiency and quality. Lead initiatives to optimize processes and implement automation while mentoring a small team. Collaborate with cross-functional t...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$111K - $167K *

Engage with clients to identify needs and drive successful adoption of quantum solutions. Collaborate with internal teams to deliver value, provide expert technical support, and foster long-term relat...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $193K *

Drive innovation in pharmacy automation software development, enhancing efficiency and accuracy. Collaborate cross-functionally to tackle complex challenges and see the impact of your contributions on...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Analyze technical sales opportunities from discovery to close, leveraging AI tools and client data to drive business cases. Collaborate with cross-functional teams to ensure seamless implementation an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$119K - $179K *

Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by shaping go-to-market strategies and driving growth in commercial banking solutions. Collaborate with cross-functional teams to translate market insights into impactful narrative...

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$130K - $155K *

Elevate your career by designing and training advanced machine learning models. Collaborate with experts to analyze data, create reinforcement learning environments, and communicate findings effective...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$330K - $500K *

Shape the future of content discovery by leading product operations and program management. Drive efficiency and innovation across teams, ensuring seamless collaboration and execution of high-impact i...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$130K - $140K *

Elevate your career by joining a dynamic team to design and implement innovative cloud solutions in a multi-cloud environment, ensuring scalability, security, and alignment with business objectives wh...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform your career by leading Microsoft Cloud security projects, deploying SIEM and XDR solutions, and enhancing customer environments. Collaborate with a dynamic team to drive innovation in Manage...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Engage with our Technical Support team to tackle complex issues for enterprise health systems. Drive incident resolution, enhance support processes, and mentor junior engineers while shaping the futur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.