Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$120K - $145K *

Shape the future of digital transformation by leading a dynamic team to deliver innovative solutions that enhance business efficiency and customer experience across multi-functional AWS programs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$207K - $250K *

Unlock your potential as you lead engineering teams in building innovative platforms and AI experiences. Collaborate across departments to drive technical direction and elevate team performance while...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Unlock AI-driven engineering transformation by collaborating with clients to enhance SDLC processes. Drive measurable improvements in delivery speed and quality through innovative solutions and hands...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$187K - $260K *

Lead the charge in shaping our marketing technology ecosystem, driving product strategy and team development while enhancing workflows and cross-channel capabilities for data-driven marketing success...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$128K - $160K *

Lead the charge in delivering innovative AI and automation solutions, translating complex business needs into technical designs. Collaborate across teams to enhance productivity and drive continuous i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$97K - $143K *

Drive innovative aerospace solutions by leading systems engineering efforts, managing requirements, and collaborating with global teams to ensure successful product development and integration in dyna...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$135K - $210K *

Lead the charge in solving complex carrier connectivity challenges in commercial insurance. Collaborate with cross-functional teams to streamline workflows and enhance product delivery, ensuring seaml...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Lead and develop a high-performing Applied AI team, driving the delivery of production AI systems while ensuring security, reliability, and operational excellence in healthcare applications...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$130K - $160K *

Drive the evolution of Stripe's authentication stack as a Backend Engineer, enhancing security and scalability while collaborating with teams to deliver innovative IAM solutions supporting enterprise...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $220K *

Lead the integration of complex defense solutions by translating tactical requirements into innovative products. Collaborate with cross-functional teams to optimize performance and drive market adopti...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$135K - $160K *

Innovate with us to modernize a .NET insurance platform, leading a DevOps team to enhance CI/CD practices, automate infrastructure, and drive scalable architecture for improved stability and performan...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$200K - $275K *

Lead the development of off-board AI evaluation frameworks to optimize safety and performance for autonomous vehicles. Collaborate with cross-functional teams to design scalable systems and enhance di...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Transportation

$85K - $97K *

Accelerate progress at our team by developing and deploying full-stack solutions. Collaborate on REST APIs, enhance legacy applications, and ensure secure coding practices while delivering high-qualit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $154K *

Lead complex projects to enhance organizational efficiency, manage timelines, and coordinate cross-functional teams. Drive strategic goals while ensuring compliance and fostering strong stakeholder re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Accelerate the development of Manufacturing Execution Systems (MES) by collaborating with clients to solve complex manufacturing challenges through innovative automation and programming solutions, whi...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$120K - $145K *

Unlock potential by driving AI security marketing initiatives, creating demos, and collaborating with cross-functional teams to enhance product visibility and adoption. Serve as the technical voice fo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Drive execution of complex technical initiatives, translating business vision into actionable programs. Collaborate with cross-functional teams to ensure alignment with company objectives and measurab...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$188K - $245K *

Advance our longitudinal patient record by leading product strategy, ensuring data integrity, and enhancing clinical utility. Collaborate with cross-functional teams to deliver a unified view of patie...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Take ownership of transformative AI solutions by embedding within business units, identifying key operational challenges, and rapidly delivering demonstrable results that drive adoption and innovation...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$86K - $165K *

Optimize test engineering solutions by analyzing hardware requirements and developing automated test stations. Collaborate with internal and external customers to ensure accurate, reliable, and repeat...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$131K - $205K *

Shape the future of electric power projects by providing expert development support, technical evaluations, and engineering design reviews. Collaborate with clients to optimize project outcomes while...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$107K - $204K *

Lead the charge in developing embedded cryptographic software for military communications. Collaborate with cross-functional teams to enhance security and reliability while managing product backlogs i...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.