Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Senior Product Security Engineer
$115K - $145K *
Lead security initiatives by collaborating with cross-functional teams to embed security in the software development lifecycle, ensuring robust protection for high-risk product areas while driving ado...
1 week ago
Senior AI / ML Engineer (LLMs)
$200K - $235K *
Transform AI/ML systems by leading end-to-end development of innovative solutions. Tackle complex challenges in medical synthesis and help define and deploy advanced features that enhance user experie...
Reposted 3 days ago
$80K - $95K *
Take ownership of complex technical issues, driving resolution and enhancing customer experience through deep problem-solving and collaboration with cross-functional teams...
Reposted yesterday
$110K - $130K *
Empower innovation by partnering with data science to build and maintain robust ML pipelines. Drive automation and observability in production systems, ensuring reliable match data at scale while coll...
2 weeks ago
Senior Software Engineer, Biggy Engineering
$187K - $220K *
Unlock potential by designing and building AI-powered solutions to enhance enterprise IT operations, collaborating directly with customers and driving impactful product features across backend and aut...
Reposted 3 days ago
$127K - $171K *
Champion high-impact deployments by leveraging data intelligence and AI to drive governance solutions in regulated industries, serving as a trusted advisor to stakeholders and delivering measurable va...
Reposted 3 weeks ago
$86K - $140K *
Champion payroll excellence by processing and reconciling payroll across multiple regions, collaborating with cross-functional teams to enhance compliance, reporting, and automation for a seamless emp...
1 week ago
Principal Security Software Engineer, PKI and Secrets Management
$201K - $309K *
Elevate security standards by leading the development of innovative software solutions. Collaborate with cross-functional teams to integrate robust security measures, ensuring the integrity of applica...
1 week ago
Senior Sales Engineer, Data Products
$125K - $160K *
Join a team that's redefining data solutions by leading technical sales efforts, collaborating with Account Managers, and driving customer success through innovative data architecture and tailored dem...
1 week ago
Senior Sales Solution Engineer
$125K - $138K *
Elevate customer experience by leading technical engagement during pre-sales. Utilize deep knowledge to craft solutions, mentor peers, and ensure seamless transitions, while remaining adaptable in a f...
Reposted 3 weeks ago
Solutions Engineer | PST or EST US | Remote
$182K - $226K *
Unlock potential by joining a dynamic team that drives customer success through technical expertise and innovative solutions, enhancing product engagement and collaboration in a fast-paced startup env...
1 week ago
Senior Global Technology Partner Marketing Manager - EST
$120K - $145K *
Drive the global marketing strategy for a technology partner ecosystem, enhancing customer experiences through seamless integrations. Collaborate with cross-functional teams to create impactful go-to...
3 weeks ago
$130K - $219K *
Engage with customers to identify key challenges and drive product innovation. Collaborate across hardware, software, and AI teams to deliver impactful solutions that enhance physical operations and g...
1 week ago
Senior Product Marketing Manager | US | Remote
$162K - $194K *
Drive growth as a Senior Product Marketing Manager, shaping messaging and campaigns for Observability products. Collaborate with cross-functional teams to enhance customer engagement and retention thr...
1 week ago
$180K - $200K *
Elevate healthcare technology by owning mobile and web apps that enhance clinician workflows. Drive product direction, prioritize initiatives, and ensure patient safety while leveraging AI to improve...
2 weeks ago
$150K - $230K *
Transform customer experiences by leading technical discovery and implementation for federal clients. Collaborate across teams to deliver cutting-edge autonomous solutions, ensuring successful deploym...
3 weeks ago
Software Engineer, Back-End - Mail (US)
$125K - $150K *
Unlock potential by joining our dynamic team to build robust back-end systems that power AI-driven workflows and enhance user experiences across platforms. Collaborate with engineers to innovate and s...
Reposted 2 days ago
Sr. Software Engineer - Sensor, macOS (Hybrid)
$140K - $220K *
Champion innovation in macOS development, driving core sensor features for endpoint protection. Collaborate with a dynamic team to enhance security capabilities, ensuring high performance and reliabil...
1 week ago
Senior Fire Protection Engineer
$92K - $166K *
Join a dynamic team to enhance the FAA's Fire Life Safety Program, ensuring compliance and safety across various facilities. Leverage your expertise in fire protection engineering to support policy de...
Today
$100K - $130K *
Unlock your potential as a Senior Financial Analyst, driving financial insights and models to support growth. Collaborate across teams to enhance forecasting accuracy and optimize performance, playing...
1 month ago
Senior Data Scientist I, Monetization
$159K - $188K *
Transform audience and measurement products by independently owning the full lifecycle, from problem framing to delivery. Collaborate with cross-functional teams to enhance data-driven advertising sol...
Reposted yesterday
$150K - $180K *
Lead the charge in delivering advanced AI-powered solutions using Python. Collaborate with cross-functional teams to tackle complex challenges and drive innovation in Generative AI across diverse proj...
Reposted 2 days ago
Partner Product Marketing Manager
$110K - $130K *
Help us shape the future of partner marketing by crafting compelling narratives that drive adoption and engagement for our Buyer Intent product line, collaborating with cross-functional teams to deliv...
Today
Senior Product Security Engineer
$120K - $150K *
Contribute to securing products throughout their lifecycle by collaborating with developers, leading design reviews, and performing penetration testing to enhance security measures and compliance post...
1 week ago
$110K - $130K *
Transform the customer experience by owning product marketing strategies that resonate with diverse industries. Collaborate closely with sales and product teams to create impactful messaging and asset...
2 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.