Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$105K - $163K *

Transform database environments by leading architecture and administration efforts across multiple platforms, ensuring compliance and performance for mission-critical applications in a dynamic, remote...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $130K *

Lead the charge in advancing automation and controls technologies across global operations, ensuring compliance and operational readiness while collaborating with international teams to implement inno...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$85K - $95K *

Drive the end-to-end delivery of complex curriculum projects, collaborating across teams to ensure high-quality outcomes that meet business and learner needs while managing risks and stakeholder expec...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$130K - $150K *

Join a dynamic team as a senior technical leader, driving innovative platform solutions and enhancing integration processes. Collaborate across teams to improve user experiences and streamline operati...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$70K - $100K *

Champion seamless customer experiences by resolving technical issues and collaborating cross-functionally. Leverage your expertise to enhance product reliability and drive customer satisfaction in a d...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$123K - $159K *

Build core AI platform capabilities that empower teams to develop, run, and scale GenAI applications, collaborating across the tech stack to deliver impactful solutions for millions of users in a fast...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Lead the charge in shaping innovative Network Observability products, driving strategy from concept to launch. Collaborate with cross-functional teams to deliver solutions that empower operators to op...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $187K *

Accelerate progress at client engagement by managing relationships, driving sales strategies, and ensuring delivery excellence. Collaborate with teams to create account plans and optimize performance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining automation in industrial testing. You'll develop robust test frameworks and simulators, ensuring seamless integration and coverage for critical protocols while collaborat...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$154K - $185K *

Join a team that's enhancing Grafana's data source plugins, ensuring reliability and seamless integration for users worldwide. Lead development efforts and collaborate to deliver world-class observabi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the architectural vision for scalable Identity Resolution platforms, driving innovation in enterprise applications and data processing. Collaborate with engineering teams to ensure robust, high-p...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $175K *

Champion the integration of AI-powered API services, ensuring reliability and scalability while bridging traditional systems with modern language models. Drive innovation in backend workflows and coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$161K - $242K *

Lead the charge in driving the cardiology portfolio's growth and modernization. Own strategy, adoption, cloud migration, and pricing while collaborating across teams to enhance patient outcomes and op...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $243K *

Lead the charge in data engineering excellence by mentoring a team, driving pipeline delivery, and translating stakeholder needs into actionable technical plans while ensuring operational accountabili...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Information Technology

$235K - $270K *

Elevate the future of transportation by leading the integration of autonomous driving technology into our robotaxi fleet. Drive cross-functional collaboration, manage risks, and ensure a seamless mark...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead engineering initiatives by developing customer relationships and delivering tailored solutions. Oversee team performance, manage workloads, and ensure engineering excellence while driving busines...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$188K - $245K *

Drive innovative UX design strategies in clinical settings, leading a talented team to enhance decision support and care coordination. Collaborate across functions to integrate AI and elevate user exp...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $130K *

Join a dynamic team to design and optimize scalable data solutions that enhance healthcare technology platforms. Collaborate with cross-functional teams to ensure data integrity and drive informed dec...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate by developing scalable applications and data pipelines, leveraging Python and cloud platforms. Collaborate with cross-functional teams to modernize enterprise systems and enhance backend serv...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $110K *

Elevate your career by joining a dynamic Technical Operations team focused on cloud-native infrastructure and Kubernetes. Collaborate across teams to enhance platform reliability and drive operational...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Lead and develop a team of Product Managers to drive AI-powered product strategy, governance, and investment decisions. Shape the organization's AI capabilities while ensuring responsible AI practices...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$159K - $273K *

Shape the future of home listings by driving supply growth and enhancing buyer experiences. Lead AI-driven initiatives to optimize inventory presentation and engagement, ensuring Redfin remains the go...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Partner with us to shape the quality strategy for a leading exam development platform. Leverage your expertise to guide multiple Agile teams, enhance automation practices, and ensure high standards ac...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$112K - $135K *

Elevate your career by designing and implementing cloud infrastructure solutions in Azure. Collaborate with teams to automate deployments, optimize CI/CD pipelines, and leverage AI tools for enhanced...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$123K - $218K *

Take ownership of complex project delivery across multiple teams, ensuring timely execution of high-stakes initiatives. Collaborate with engineers and researchers to optimize project management practi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.