Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$84K - $87K *

Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Grow your career with a dynamic frontend engineering team focused on building robust platforms. Collaborate across teams to enhance product features, ensure high-quality deliverables, and drive innova...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$89K - $139K *

Drive the transformation of employee experiences by leading a multi-year Digital Employee Experience (DEX) program. Oversee analytics, enhance productivity, and implement AI-driven solutions to optimi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $165K *

Accelerate progress at multi-site data center and AI programs valued over $25M. Lead diverse teams to ensure successful delivery, budget management, and customer satisfaction while driving executive c...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$132K - $251K *

Drive your career forward by leading a dynamic team in developing innovative real-time embedded software for military GPS and PNT applications, overseeing all phases of the software engineering lifecy...

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $170K *

Transform enterprise software systems by leading design and development efforts, ensuring scalable, secure applications that meet federal mission needs while mentoring engineers and driving best pract...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $270K *

Unlock your potential by managing ML systems at scale, ensuring uptime and observability. Collaborate on deploying and scaling models, while enhancing platform reliability through advanced engineering...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$136K - $170K *

Drive impactful infrastructure solutions by collaborating with engineering teams to resolve blockers, execute migrations, and develop tooling. Leverage your expertise to enhance platform adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Tackle complex projects as a dual Project Manager and Scrum Master, leading AI and ML initiatives. Drive delivery, manage budgets, and facilitate agile teams while ensuring stakeholder alignment and p...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining product management by building innovative features from concept to launch. Leverage AI tools to enhance efficiency and drive product operations, ensuring seamless deliver...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $150K *

Transform your career by joining a dynamic team focused on enhancing security compliance for cloud services. Leverage your expertise in IT security to assess architectures, guide vendors, and ensure a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Innovate software solutions for precision farming, leading design and testing while mentoring team members. Drive continuous improvement and champion best practices in a collaborative environment to e...

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Drive the development and integration of advanced nuclear energy systems by applying systems engineering methods to translate objectives into clear, verifiable requirements and solutions, while collab...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$190K - $220K *

Partner with us to tackle complex engineering challenges, leveraging deep expertise in TypeScript, Postgres, and AWS. Collaborate closely with our VP of Engineering to innovate and deliver impactful p...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$116K - $171K *

Elevate customer success by partnering with developers to implement solutions, troubleshoot technical issues, and enhance product features. Your insights will drive improvements across teams, ensuring...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$95K - $159K *

Elevate your career by ensuring software quality and compliance in innovative cloud and AI/ML systems, collaborating with cross-functional teams to enhance product development and uphold stringent saf...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$101K - $135K *

Join a team that's shaping the future of healthcare technology by designing and enhancing our build and delivery infrastructure. Collaborate with architects and developers to implement best practices...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Transform customer engagement by leading a team of Solutions Architects, driving technical strategy and operational excellence across the India region while ensuring alignment with cross-functional pa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in defining and executing enterprise architecture strategies, ensuring alignment with business goals while fostering innovation and governance across technology platforms, data integra...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in transforming our core banking platform by driving technical architecture and integration. Collaborate with cross-functional teams to deliver scalable solutions that enhance operatio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$128K - $205K *

Elevate your career by owning the TA tech stack, driving integrations, and enhancing system efficiency. Collaborate with cross-functional teams to optimize processes and lead vendor relationships, all...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Transform enterprise architecture by defining target-state frameworks, guiding technology roadmaps, and ensuring compliance in a regulated environment. Collaborate with leaders to drive modernization...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$199K - $276K *

Drive enhancements to our unsecured underwriting models through rigorous research and experimentation. Collaborate with engineering teams to translate findings into scalable solutions that improve cre...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$171K - $285K *

Transform your career by leading a high-performing engineering team to deliver innovative digital solutions. Collaborate across departments to drive technology strategy and modernize capabilities, ens...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$115K - $158K *

Join a dynamic team to develop cutting-edge AI for audio experiences. You'll design, train, and optimize machine learning models, collaborating with engineers to enhance product capabilities while pus...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.