Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

$135K - $160K *

Empower startups to achieve rapid compliance with Vanta's AI-driven solutions. As a Staff Product Designer, you'll shape the customer experience from onboarding to activation, driving product strategy...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $115K *

Optimize security measures by leading technical solutions to mitigate information risks. Ensure compliance with corporate policies and oversee incident response, safeguarding all computing platforms a...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Lead the charge in enhancing engineering excellence by managing cross-functional teams, driving continuous improvement, and optimizing performance metrics to boost business agility and profitability i...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$315K - $370K *

Join a team that's redefining offensive security by leading engineering efforts to transform research into scalable, customer-facing products. Drive strategy, execution, and innovation across multiple...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Engineer innovative cloud-native applications, developing scalable backend services and modern web solutions using Golang and React. Collaborate with cross-functional teams to solve complex challenges...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $142K *

Transform workforce insights into actionable strategies by leveraging HR systems and analytics. Collaborate with cross-functional teams to enhance decision-making through compelling data visualization...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$175K - $185K *

Unlock potential by leading global product strategies that drive growth and innovation. Collaborate cross-functionally to prioritize customer needs, enhance product performance, and support internatio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $285K *

Shape the future of database protection by owning the Oracle roadmap, collaborating with engineering teams, and driving cross-database initiatives to enhance recovery solutions for critical enterprise...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$175K - $195K *

Shape the future of enterprise AI solutions by leading technical delivery and client engagement. Utilize your expertise in AI platforms to create measurable outcomes and drive adoption, while collabor...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $180K *

Lead the charge in driving agile execution across product and engineering teams, managing digital product launches and enhancing client value through innovative solutions. Collaborate cross-functional...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$84K - $124K *

Optimize advanced material planning activities across customer projects, ensuring procurement readiness and risk identification while facilitating seamless transitions from planning to purchasing exec...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$128K - $226K *

Unlock potential by leading the delivery of APIs and integrations that enhance healthcare tools. Collaborate with engineering teams to ensure reliable, user-friendly solutions that drive business grow...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$179K - $254K *

Join a team that's driving the future of mobility and IoT! Oversee product lifecycles, collaborate with executives, and navigate complex networks to align cutting-edge solutions with customer needs an...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Empower our revenue team by building and scaling GTM systems. Collaborate with sales, finance, and engineering to enhance Salesforce and optimize workflows, ensuring accurate forecasting and seamless...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Transform product capabilities by leading strategy and execution for shared workflows, ensuring seamless integration and user experience across platforms. Drive measurable outcomes through customer in...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead innovative product development in power connectors and cable assemblies, driving technical excellence and cross-functional collaboration to deliver high-quality solutions that meet market demands...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$101K - $174K *

Elevate your career by joining a dynamic team to design, deploy, and optimize a secure cloud-native platform. Collaborate across functions to enhance delivery pipelines and ensure reliability in a fas...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$92K - $158K *

Join a team that's dedicated to enhancing a secure PaaS for federal applications. You'll troubleshoot complex issues, support tenant operations, and collaborate on platform improvements, ensuring reli...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Shape the future of cybersecurity by engineering and enhancing robust security controls. As a senior practitioner, you'll lead incident response, vulnerability management, and security architecture, m...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $300K *

Shape the future of AI by engaging developers and partners to build, test, and launch AI agents on our cutting-edge platform. You'll create technical content, lead workshops, and cultivate feedback to...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$137K - $202K *

Shape the future of compensation products by owning the development and management of a comprehensive range-setting tool and analytics roadmap that enhances productivity for Compensation Partners and...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Transform the data platform by owning product direction and delivery. Collaborate across teams to prioritize needs, streamline processes, and ensure engineering focuses on impactful projects while enh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $190K *

Empower our team to drive innovation by developing crucial AI tools that enhance operational efficiency. Oversee governance, training, and metrics to ensure impactful adoption across departments while...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Lead high-impact, cross-functional technical programs, translating business vision into structured execution. Drive Agile practices, enhance team efficiency, and ensure alignment with company objectiv...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$67K - $92K *

Join a team that's dedicated to ensuring software quality through automated testing. Collaborate with developers, execute test cases, and leverage AI tools to enhance testing processes while participa...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.