Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$200K - $275K *

Lead and optimize cloud infrastructure for simulation frameworks, driving team performance and technical strategy. Collaborate cross-functionally to enhance validation processes and ensure robust soft...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$125K - $150K *

Explore innovative solutions as a Senior Mobile Engineer, leading the design and architecture of mission-critical apps that empower our delivery fleet and operations teams, ensuring reliability and ef...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$120K - $145K *

Pioneer the future of technical content as you drive strategy and execution for Render's content factory, ensuring accuracy and relevance for AI agents and developers. Collaborate closely with teams t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in managing a technical team focused on Gitaly, driving performance, scalability, and maintainability while fostering a culture of accountability and ownership across distributed teams...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$183K - $255K *

Lead the charge in defining enterprise architecture strategies that drive modernization and transformation across technology domains, engaging stakeholders and mentoring teams to achieve excellence in...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$82K - $123K *

Champion AI innovation by driving tool adoption, engineering practices, and workforce enablement across the enterprise. Collaborate with cross-functional teams, influencing leaders and building future...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$105K - $165K *

Drive the design and management of AWS EKS Kubernetes clusters, ensuring high availability and security. Collaborate with cross-functional teams to optimize cloud infrastructure and automate processes...

Des Moines, IARemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $160K *

Lead the charge in transforming data accessibility for product teams and AI agents. Oversee a team of data engineers to build a robust platform that ensures secure, reliable data usage across the orga...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$172K - $240K *

Join a team that's redefining AI security! As a Principal AI Security Engineer, you'll lead assessments, design controls, and partner with teams to ensure safe AI adoption across the enterprise, drivi...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $199K *

Lead the charge in shaping innovative learning programs that drive organizational growth. Collaborate with stakeholders to enhance professional development and ensure the strategic execution of initia...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Partner with us to optimize and scale our Ruby on Rails applications, ensuring high availability and performance. Leverage your expertise in cloud infrastructure and Site Reliability Engineering to dr...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by joining a dynamic team focused on validating and optimizing Azure developer desktops. You'll design automated tests, ensure security compliance, and enhance performance metrics...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in managing complex technical projects across IT, Security, and Compliance. Engage with customers to translate technical needs into actionable plans while ensuring seamless internal co...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Drive the development and optimization of GTM strategies, leveraging automation and campaign execution across multiple platforms to enhance pipeline generation and account prioritization in a dynamic...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Lead the charge in building a secure, self-service developer sandbox on Azure, delivering non-persistent desktops and managing the entire stack from landing zone to golden image while ensuring complia...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$136K - $181K *

Champion delivery excellence by leading cross-functional teams to enhance supplier performance and resolve technical challenges in manufacturing processes, driving cost reductions and ensuring optimal...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $160K *

Unlock innovative AI solutions by deploying and scaling advanced workflows. Collaborate with clients to transform business challenges into reliable, AI-driven applications, leveraging cutting-edge tec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $190K *

Transform security solutions across multiple domains, driving technical direction and collaboration to address high-risk items and enhance Meta's security posture company-wide. Lead cross-functional t...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $185K *

Unlock potential by designing and maintaining scalable backend systems for complex data integrations. Collaborate with partners to enhance operational efficiency and reliability, ensuring seamless dat...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $219K *

Drive the vision for Samsara device installations, enhancing user experiences and ensuring rapid, accurate setups. Collaborate with cross-functional teams to optimize the install process, making impac...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the charge in developing innovative AI software solutions, enhancing system performance, and collaborating with teams to align with IT roadmaps. Drive improvements through analysis and ensure sea...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$104K - $176K *

Lead the strategy and optimization for a high-traffic B2B website, aligning partners and driving performance through experimentation and content governance. Collaborate with cross-functional teams to...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Transform project delivery by leading software implementations, ensuring timely and budget-friendly outcomes while fostering strong stakeholder relationships and navigating complex environments with c...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $173K *

Innovate and lead software solutions for the iSeries environment, driving scalable systems and mentoring junior developers. Collaborate with cross-functional teams to enhance mobility payment solution...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$85K - $125K *

Accelerate progress at the forefront of mobile development by leveraging AI tools to enhance iOS applications. Collaborate with cross-functional teams to deliver high-quality, customer-centric marketp...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.