Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Principle Machine Learning Engineer
$160K - $200K *
Lead the technical direction for AI agent quality, defining metrics and evaluation systems. Collaborate with cross-functional teams to enhance agent performance and ensure quality in production enviro...
2 weeks ago
Software Engineer - Technology
$108K - $115K *
Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...
1 week ago
Principal Computer Systems Engineer - Onsite
$107K - $204K *
Join a dynamic team as you design and integrate cutting-edge avionics computing systems. Collaborate across disciplines to translate requirements into architecture, ensuring performance and compliance...
Reposted 2 weeks ago
Senior Technical Program Manager (Remote, US)
$185K - $225K *
Lead the charge in delivering complex, cross-functional programs that drive innovation in consumer energy products. Collaborate with diverse teams to establish frameworks, manage risks, and ensure suc...
3 weeks ago
$110K - $130K *
Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...
3 weeks ago
Principal Software Engineer - Emerging Technology & AI - Remote
$177K - $236K *
Transform the future of technology as a Principal Software Engineer, leading AI experimentation and prototyping. Collaborate across teams to design scalable solutions, mentor engineers, and drive inno...
1 week ago
$125K - $140K *
Elevate your career by designing and managing AWS environments, automating CI/CD, and ensuring robust application delivery. Collaborate with cross-functional teams for end-to-end ownership and enhance...
Reposted 2 days ago
Software Engineer, Identity Platform
$125K - $150K *
Join a team that's redefining identity management across diverse platforms. You'll architect secure authentication and authorization systems, ensuring seamless access for users and organizations while...
2 weeks ago
$210K - $300K *
Join a dynamic team as a Games Product Manager, driving engagement and retention for a diverse portfolio of mobile and cloud titles. Collaborate with cross-functional partners to create compelling pla...
Today
$155K - $210K *
Lead complex programs and strategic client engagements, driving technology transformation and sustainable business value. Act as a trusted adviser to C-level stakeholders, shaping program vision and e...
3 weeks ago
$108K - $140K *
Unlock potential by leading verification and validation for regulated medical device software. Collaborate with cross-functional teams to ensure compliance and quality in bioinformatics and lab automa...
Today
Security Engineer, Infrastructure Security
$120K - $145K *
Join us to enhance the security posture of our production platform. As an Infrastructure Security Engineer, you'll drive remediation efforts, build security frameworks, and collaborate with teams to p...
1 week ago
Program Manager, Product Data Operations, Family of Apps
$120K - $145K *
Lead the charge in managing cross-functional programs that enhance AI data quality and evaluation. Collaborate with diverse teams to translate product needs into actionable plans, ensuring efficient d...
1 week ago
$90K - $128K *
Transform data-driven applications by leveraging your software development expertise. Collaborate with multidisciplinary teams to design, implement, and enhance solutions that improve decision-making...
6 days ago
$120K - $140K *
Innovate cloud solutions by designing and automating infrastructure in Cloud.gov and Azure. Collaborate with teams to enhance performance and security, driving impactful results for clients while shap...
Reposted yesterday
Full Stack Java/Angular Developer
$110K - $130K *
Lead the charge in enhancing complex Federal applications by designing, developing, and maintaining full-stack solutions using Java and Angular. Collaborate in an Agile environment to deliver secure...
Today
Associate Staff Engineer - INFOR M3 Technical Consultant
$100K - $120K *
Optimize your career as an Infor M3 Technical Consultant, leveraging 3-5 years of expertise in integrations and development. Collaborate with teams to design and support seamless enterprise solutions...
3 weeks ago
Lead Forward Deployed Engineer (AI Enablement)
$194K - $272K *
Elevate AI solutions by leading engineering efforts that transform business workflows. Collaborate with teams to identify opportunities, prototype solutions, and implement scalable AI applications tha...
2 weeks ago
Senior Software Engineer, Identity & Regulatory Platform
$135K - $160K *
Lead the development of AI-driven systems for onboarding and compliance, enhancing customer journeys for major financial institutions. Collaborate with cross-functional teams to optimize processes and...
Today
Senior Embedded Software Engineer
$86K - $165K *
Join a dynamic software development team to innovate cybersecurity solutions for connected systems. Collaborate with experts to tackle complex challenges and enhance technologies for critical aerospac...
2 weeks ago
Senior Electrical Engineer, Installation
$116K - $170K *
Champion electrical engineering excellence by leading installation standards, ensuring compliance, and driving continuous improvement in warehouse systems. Collaborate with cross-functional teams to e...
Yesterday
Staff Product Manager, Technical
$160K - $220K *
Shape the future of product strategy by leading complex client engagements, managing the full product lifecycle, driving cross-functional alignment, and mentoring teams to deliver impactful solutions...
Reposted 3 weeks ago
Senior Program Manager, People Data Access & Governance
$123K - $207K *
Champion the design and ownership of a robust People Data Access & Governance framework, ensuring responsible data access while partnering with cross-functional teams to navigate compliance and ethica...
Reposted 2 weeks ago
Senior Product Security Engineer
$173K - $255K *
Join a dynamic team to enhance product security throughout the development lifecycle. Collaborate with engineering and product teams to identify vulnerabilities, automate processes, and implement secu...
1 week ago
Principal Engineer Team Lead, Simulation Infrastructure
$200K - $275K *
Lead and optimize cloud infrastructure for simulation frameworks, driving team performance and technical strategy. Collaborate cross-functionally to enhance validation processes and ensure robust soft...
Reposted 2 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.