Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$160K - $200K *

Lead the technical direction for AI agent quality, defining metrics and evaluation systems. Collaborate with cross-functional teams to enhance agent performance and ensure quality in production enviro...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$108K - $115K *

Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$107K - $204K *

Join a dynamic team as you design and integrate cutting-edge avionics computing systems. Collaborate across disciplines to translate requirements into architecture, ensuring performance and compliance...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$185K - $225K *

Lead the charge in delivering complex, cross-functional programs that drive innovation in consumer energy products. Collaborate with diverse teams to establish frameworks, manage risks, and ensure suc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Empower your career as a Platform Engineer, driving innovation in system architecture and cloud technologies. Collaborate with cross-functional teams to enhance platform efficiency and guide junior en...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$177K - $236K *

Transform the future of technology as a Principal Software Engineer, leading AI experimentation and prototyping. Collaborate across teams to design scalable solutions, mentor engineers, and drive inno...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $140K *

Elevate your career by designing and managing AWS environments, automating CI/CD, and ensuring robust application delivery. Collaborate with cross-functional teams for end-to-end ownership and enhance...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join a team that's redefining identity management across diverse platforms. You'll architect secure authentication and authorization systems, ensuring seamless access for users and organizations while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$210K - $300K *

Join a dynamic team as a Games Product Manager, driving engagement and retention for a diverse portfolio of mobile and cloud titles. Collaborate with cross-functional partners to create compelling pla...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$155K - $210K *

Lead complex programs and strategic client engagements, driving technology transformation and sustainable business value. Act as a trusted adviser to C-level stakeholders, shaping program vision and e...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $140K *

Unlock potential by leading verification and validation for regulated medical device software. Collaborate with cross-functional teams to ensure compliance and quality in bioinformatics and lab automa...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join us to enhance the security posture of our production platform. As an Infrastructure Security Engineer, you'll drive remediation efforts, build security frameworks, and collaborate with teams to p...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in managing cross-functional programs that enhance AI data quality and evaluation. Collaborate with diverse teams to translate product needs into actionable plans, ensuring efficient d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $128K *

Transform data-driven applications by leveraging your software development expertise. Collaborate with multidisciplinary teams to design, implement, and enhance solutions that improve decision-making...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $140K *

Innovate cloud solutions by designing and automating infrastructure in Cloud.gov and Azure. Collaborate with teams to enhance performance and security, driving impactful results for clients while shap...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in enhancing complex Federal applications by designing, developing, and maintaining full-stack solutions using Java and Angular. Collaborate in an Agile environment to deliver secure...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Optimize your career as an Infor M3 Technical Consultant, leveraging 3-5 years of expertise in integrations and development. Collaborate with teams to design and support seamless enterprise solutions...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$194K - $272K *

Elevate AI solutions by leading engineering efforts that transform business workflows. Collaborate with teams to identify opportunities, prototype solutions, and implement scalable AI applications tha...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$135K - $160K *

Lead the development of AI-driven systems for onboarding and compliance, enhancing customer journeys for major financial institutions. Collaborate with cross-functional teams to optimize processes and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$86K - $165K *

Join a dynamic software development team to innovate cybersecurity solutions for connected systems. Collaborate with experts to tackle complex challenges and enhance technologies for critical aerospac...

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$116K - $170K *

Champion electrical engineering excellence by leading installation standards, ensuring compliance, and driving continuous improvement in warehouse systems. Collaborate with cross-functional teams to e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $220K *

Shape the future of product strategy by leading complex client engagements, managing the full product lifecycle, driving cross-functional alignment, and mentoring teams to deliver impactful solutions...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$123K - $207K *

Champion the design and ownership of a robust People Data Access & Governance framework, ensuring responsible data access while partnering with cross-functional teams to navigate compliance and ethica...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$173K - $255K *

Join a dynamic team to enhance product security throughout the development lifecycle. Collaborate with engineering and product teams to identify vulnerabilities, automate processes, and implement secu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K - $275K *

Lead and optimize cloud infrastructure for simulation frameworks, driving team performance and technical strategy. Collaborate cross-functionally to enhance validation processes and ensure robust soft...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.