Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$154K - $278K *

Drive innovation in advanced maritime technologies, leading multidisciplinary teams to deliver cutting-edge solutions for critical defense missions. Oversee program execution, business development, an...

United StatesRemote

2 days ago

  •   15+ years exp.  •   Technical Services

$120K - $145K *

Champion quality assurance initiatives by leveraging Python and AI-assisted practices. Drive automation improvements, enhance testing efficiency, and collaborate with cross-functional teams to elevate...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$104K - $166K *

Unlock your potential as you build and enhance a cutting-edge data platform, driving innovation in federal background investigations. Collaborate in a high-trust, remote environment while ensuring dat...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$200K - $250K *

Innovate and shape the technical strategy for a cutting-edge exchange platform. Lead high-impact initiatives, mentor engineers, and drive architectural decisions in a regulated environment to enhance...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $225K *

Join a team that's driving innovation in AI by developing scalable backend systems in Go, Python, and Java. Tackle complex challenges while enhancing distributed architectures to empower high-performa...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Empower engineering teams to innovate advertiser tools, driving technical strategy and delivery while enhancing user experience across self-service and managed workflows in a dynamic ad tech environme...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Technical Services

$138K - $163K *

Lead and inspire software engineering teams to deliver innovative solutions, ensuring high-quality standards and alignment with business goals. Foster a collaborative culture while driving continuous...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$138K - $163K *

Drive the evolution of software solutions for healthcare quality reporting, leading engineering teams to deliver innovative, high-quality products while fostering a culture of collaboration and contin...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $175K *

Lead the charge in architecting scalable Azure solutions across multi-team programs, aligning client goals with innovative designs. Mentor teams, drive modernization efforts, and ensure high-quality d...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$175K - $250K *

Shape the cloud infrastructure for AI agents, ensuring secure, scalable solutions that enhance customer workflows. Lead architectural decisions, establish standards, and drive innovation in a dynamic...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$250K - $250K+*

Pioneer the future of developer AI by architecting scalable backend systems that enhance real-world product experiences through developer-centric cloud infrastructure...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Engage in designing and optimizing AI solutions to enhance automation and analytics, collaborating across teams to integrate advanced AI capabilities into core products, while ensuring ethical standar...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$174K - $215K *

Architect the future of vulnerability intelligence by owning product strategy, roadmap, and AI integration. Collaborate with engineering and analysts to deliver impactful solutions that enhance custom...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$86K - $165K *

Lead the charge in developing cutting-edge embedded cryptographic software for military communications. Collaborate with cross-functional teams to enhance security and reliability while managing Agile...

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Innovate and lead full-stack application development across diverse sectors, ensuring secure, scalable solutions. Collaborate with teams to transform concepts into market-ready products while establis...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$104K - $153K *

Unlock your potential by leading the technical delivery of workforce applications. Collaborate with teams to enhance productivity through automation, AI, and integrations, ensuring secure and efficien...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Champion cloud and application security by enhancing AWS practices, collaborating with cross-functional teams, and driving continuous improvement to ensure secure and compliant environments...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $220K *

Engage with clients to transform business challenges into AI solutions. Collaborate in a multidisciplinary team to develop prototypes and integrate AI applications using AWS services, ensuring quality...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$136K - $181K *

Lead the charge in enhancing supplier performance through technical expertise, project management, and cross-functional collaboration to drive product delivery improvements and cost reductions in manu...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$116K - $155K *

Unlock potential by leading supplier performance initiatives, coordinating cross-functional teams, and driving manufacturing improvements to enhance product delivery and resolve technical challenges i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$90K - $108K *

Champion high-impact strategic initiatives, collaborating with executives to drive alignment and measurable results across the organization while navigating complexity and change...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$120K - $140K *

Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$220K - $250K *

Drive the product roadmap for Unify Release Orchestration, enhancing developer experience while coordinating releases across multiple services, engaging customers, and leading initiatives for AI-nativ...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$220K - $270K *

Join a team that's pushing the boundaries of machine learning in autonomous vehicles. Enhance driving capabilities, lead innovative teams, and drive commercial-scale solutions with cutting-edge techno...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Transportation

$135K - $160K *

Lead the charge in quality and validation readiness for complex programs, uniting Engineering, Product, and Customer Success teams. Utilize AI and automation to streamline processes, enhance delivery...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.