Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Senior Manager, Machine Learning Engineering
$230K - $290K *
Lead the charge in optimizing ad performance through innovative algorithms and machine learning. Collaborate with cross-functional teams to enhance advertising effectiveness and drive business success...
5 days ago
Principal Program Manager, Solution Sales
$170K - $222K *
Drive strategic transformation initiatives across Product, GTM, and Operations. Lead cross-functional teams, manage complex portfolios, and deliver measurable results while fostering clarity and accou...
1 week ago
$95K - $159K *
Empower the future of medical technology by ensuring the highest quality in embedded systems. Collaborate with cross-functional teams to drive compliance and innovation in software development for lif...
1 week ago
Fullstack Software Engineer (Frontend Focused)
$125K - $150K *
Join a team that's redefining mental health technology by developing a cutting-edge brain stimulator platform. Lead fullstack development, enhance user experience, and mentor a talented engineering te...
2 days ago
Senior Foundry Integration Engineer
$126K - $173K *
Drive integration strategies to enhance silicon photonic fabrication, collaborating with foundries to evolve processes from development to production while ensuring robust performance and reproducibil...
Reposted today
$150K - $180K *
Lead the design and development of complex software systems, ensuring architectural consistency and best practices. Collaborate with teams to deliver scalable solutions while mentoring engineers and d...
1 week ago
$120K - $145K *
Accelerate your career by designing and optimizing secure, scalable cloud infrastructure. Collaborate with cross-functional teams to enhance operational efficiency and ensure high availability for glo...
3 weeks ago
Staff Application Security Engineer
$225K - $281K *
Shape the future of application security by leading strategy and initiatives across teams. Drive secure design and standards, mentor engineers, and tackle complex security challenges in a collaborativ...
2 weeks ago
Senior QA Automation Engineer - SDET
$100K - $120K *
Drive quality assurance as a Senior QA Automation Engineer, enhancing our distributed database platform through designing automated tests, validating features, and improving release processes while wo...
Reposted 6 days ago
Staff/Principal Design Systems Lead
$150K - $180K *
Drive the evolution of our design system by building foundational infrastructure that empowers designers, engineers, and AI agents to create cohesive, high-quality experiences while leading a growing...
1 week ago
$198K - $233K *
Shape AI product strategy by synthesizing trends, customer needs, and tech capabilities. Collaborate with engineering and design to drive innovation, enabling AI solutions that deliver genuine custome...
1 week ago
Intermediate Fullstack Engineer, Subscription Lifecycle
$115K - $194K *
Lead the development of fullstack features for subscription management, enhancing customer experiences and ensuring reliable billing workflows. Collaborate with cross-functional teams to deliver safe...
Yesterday
$150K - $180K *
Join a team that's shaping the future of platform engineering, driving innovation across cloud, DevOps, and site reliability. This role empowers you to build core services, enhance architecture, and m...
Reposted 2 weeks ago
Senior Manager - Software Development Engineering
$106K - $284K *
Drive innovative software development strategies while leading cross-functional teams to deliver high-quality solutions. Foster collaboration, mentor talent, and manage project timelines to achieve or...
1 week ago
Senior Manager - Software Development Engineering
$106K - $260K *
Lead a high-performing team to architect innovative AI solutions that empower business transformation. Drive AI initiatives from ideation to deployment while fostering collaboration across functions f...
Reposted 2 weeks ago
$120K - $140K *
Transform user experiences by building and enhancing robust software solutions across frontend and backend layers, focusing on customer-facing AI products to ensure quality and safety in delivery...
Reposted 5 days ago
$190K - $210K *
Explore innovative solutions as you lead the design and architecture of scalable healthcare applications, mentor engineers, and collaborate with cross-functional teams to enhance patient experiences a...
2 days ago
$130K - $160K *
Unlock potential by leading mobile app development, shaping user experiences, and driving technical direction in a fast-paced environment. Collaborate with cross-functional teams to deliver intuitive...
3 weeks ago
Senior Technical Program Manager
$130K - $150K *
Lead the charge in driving program delivery and portfolio management for a dynamic Security team, ensuring effective execution of enterprise initiatives while fostering cross-functional collaboration...
3 weeks ago
$68K - $131K *
Optimize cutting-edge cybersecurity solutions by leading innovative research and development efforts. Collaborate with multidisciplinary teams to tackle complex challenges in embedded systems and comm...
3 weeks ago
Senior Software Engineer(HYBDRID - DALLAS, TX LOCAL CANDIDATES ONLY)
$120K - $145K *
Transform software solutions by leading architecture and design efforts, mentoring teams, and driving modernization initiatives. Collaborate across divisions to enhance public services while ensuring...
1 week ago
$150K - $180K *
Drive the technical design and delivery of innovative AI agent solutions, leading a team to ensure operational readiness and quality. Collaborate with stakeholders to define requirements and guide eng...
Reposted 1 month ago
Senior Engineering Manager, Containers
$150K - $180K *
Join a dynamic team to drive technical vision and operational excellence in cloud-native platforms. Lead engineering efforts, champion security practices, and empower talent while ensuring system stab...
4 weeks ago
Staff Backend Engineer - Submission Processing
$222K - $314K *
Drive innovation by designing and implementing LLM-based systems that tackle complex problems in data processing, empowering the team with your technical direction and expertise while overseeing impac...
Reposted 6 days ago
Principal Product Manager, Pro
$170K - $205K *
Unlock the potential of our Pro offering by leading product strategy and roadmap. Collaborate across teams to enhance customer experiences for short-term rental operators and HOAs, ensuring scalable s...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.