Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Drive enterprise solution implementations by leading requirements analysis, designing scalable architectures, and delivering innovative solutions. Collaborate with teams to ensure quality and manage c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $160K *

Drive your career forward by developing cutting-edge control planes for AI infrastructure. Collaborate with a dynamic team to enhance cloud-native orchestration platforms, leveraging your expertise in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $158K *

Join a dedicated team to lead the software development efforts for private brand growth. Empower engineers to create innovative solutions while overseeing project delivery and fostering a collaborativ...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Champion the delivery of innovative data solutions, leading cross-functional teams to modernize platforms and drive AI integration. Ensure project success through effective management of scope, qualit...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$193K - $285K *

Join a team that's redefining security engineering by designing and delivering innovative, multi-domain security services. Collaborate across teams to enhance physical and cloud security, ensuring ope...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$190K - $315K *

Shape the future of visual design for an enterprise design system, leading the evolution of its visual language and guiding teams to create consistent, high-quality experiences across products and maj...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$120K - $145K *

Join a team that's pioneering the deployment of scalable AI systems, focusing on building robust APIs, optimizing infrastructure, and ensuring reliable operations in a dynamic environment. Drive innov...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Engage in comprehensive program management for data center operations, ensuring seamless transitions from construction to live operations. Shape maintainability, drive incident improvements, and enhan...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$244K - $409K *

Drive the development of a global SME organization, leading regional teams to enhance technical selling and product direction. Transform ambiguity into structure while mentoring leaders and collaborat...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Explore a pivotal role in shaping cloud infrastructure and DevOps practices. Lead initiatives to enhance software delivery, optimize processes, and mentor teams while ensuring compliance and security...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Lead the charge in designing and implementing innovative software systems for cutting-edge healthcare SaaS platforms, driving technical excellence and strategic collaboration across teams to achieve i...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$135K - $160K *

Elevate developer engagement by representing Render at events, crafting workshops, and shaping technical direction. Drive community feedback into product enhancements while building strong relationshi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$111K - $192K *

Engage in full-stack software development, collaborating with teams to enhance features and performance. Utilize modern technologies to build secure, scalable applications for military and government...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$115K - $172K *

Shape the future of healthcare by leading complex data ingestion initiatives. Collaborate with cross-functional teams to drive program delivery, manage risks, and ensure operational excellence while t...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Develop and optimize a scalable, geo-distributed database solution while leading a skilled team. Engage in deep technical challenges to enhance performance and reliability across diverse environments...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in designing and evolving scalable cloud infrastructure, driving architectural strategy, and enhancing operational culture while collaborating with cross-functional teams to meet ambit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $150K *

Transform your career by leveraging your AWS expertise in a dynamic DevOps role. Collaborate with a hands-on team to enhance infrastructure and streamline development processes while tackling complex...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$130K - $155K *

Optimize and implement scalable, secure infrastructure solutions across Windows, Citrix, AWS, and Azure. Drive automation and collaborate with teams to design zero-trust architectures, enhancing infra...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Transform AI infrastructure by designing and maintaining production-grade systems across multiple cloud providers. Engage in hands-on architecture decisions, ensuring reliability, security, and automa...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$108K - $130K *

Transform engineering capabilities by leading cross-functional teams to deliver scalable, resilient technology solutions. Drive best practices, influence architectural decisions, and enhance moderniza...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$230K - $270K *

Lead technical direction for backend services managing licensing and entitlements. Shape scalable solutions across accounts, ensuring data correctness and operational excellence. Collaborate with Prod...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$199K - $235K *

Elevate your career as you design and maintain backend services that manage customer entitlements and usage workflows. Collaborate with cross-functional teams to ensure data integrity and deliver impa...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$138K - $165K *

Drive GitLab's Secret Detection and Vulnerability Research efforts to shape security product outcomes. Own the detection lifecycle, ensure content quality, and leverage AI to enhance operational effic...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $194K *

Lead a dynamic Support Engineering team, enhancing customer experiences through AI-driven solutions, mentorship, and scalable processes while fostering a culture of growth and accountability...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Empower AI innovation by designing and building robust tooling for deploying AI agents in production. Collaborate with cross-functional teams to enhance infrastructure reliability and developer experi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.