Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$122K - $176K *

Lead the charge in evolving a cutting-edge financial assistant, enhancing user experience through innovative features and AI integration while collaborating with cross-functional teams in a dynamic st...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$225K - $265K *

Lead the charge in developing a high-performing engineering team focused on firewall validation and security. Drive collaboration across technical and product teams while fostering an inclusive enviro...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$142K - $186K *

Pioneer a data-driven culture by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure product data integrity and empower stakeholders with self-service insights, d...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $155K *

Lead the charge in creating cutting-edge embedded software solutions for autonomous mobile robotics. Drive technical excellence, oversee collaborative engineering efforts, and ensure high reliability...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$122K - $160K *

Transform the future of endpoint management by developing innovative solutions that enhance security and performance across diverse platforms, collaborating with a dynamic team to deliver impactful so...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $185K *

Unlock potential by driving innovative infrastructure solutions for scalable deployments, collaborating with customers to refine requirements, and enhancing operational efficiency through automation a...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$131K - $164K *

Join a team that's redefining restaurant technology by building robust mobile applications. As a Senior Software Engineer II, you'll lead feature delivery, optimize performance, and collaborate across...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$101K - $140K *

Drive the evolution of Business Systems by integrating automation and AI into our go-to-market processes. Collaborate with cross-functional teams to build scalable systems that enhance efficiency and...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $125K *

Champion data engineering excellence by designing and maintaining robust data pipelines and analytics solutions. Collaborate with stakeholders to enhance data quality and support enterprise-level data...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $180K *

Transform cancer care by developing AI biomarkers through collaboration with ML scientists and clinical partners, enhancing model robustness and interpretability across diverse datasets to improve pat...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Join a team that's developing cutting-edge embedded software for agricultural machinery. Collaborate in an Agile environment to create, test, and debug software solutions that enhance hardware integra...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Lead and scale a dynamic engineering organization, driving execution and innovation while mentoring managers and aligning cross-functional priorities to deliver impactful solutions...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$153K - $166K *

Join a team that's shaping the future of AI governance in software development. As a Senior Engineer, you'll design policies and tools that ensure safe, effective use of AI coding agents, empowering d...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$140K - $175K *

Shape technical innovation by leading cross-team efforts in system architecture and development. Drive scalable improvements, mentor peers, and influence business outcomes while ensuring long-term mai...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K *

Lead the charge in developing innovative full-stack solutions that enhance workflow automation in wealth management. Collaborate with a dynamic team to create impactful features using modern technolog...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$230K - $360K *

Elevate customer success by designing and deploying innovative Gen AI and ML solutions. Collaborate with stakeholders to translate complex needs into impactful AI tools, ensuring reliability and busin...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$170K - $200K *

Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$252K - $300K *

Unlock potential by leading the technical strategy for Data Labs, guiding engineering teams to innovate AI training solutions, and shaping the future of model evaluation and deployment in a rapidly ev...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Contribute to the evolution of Support Operations by leading system implementations, optimizing workflows, and enhancing team collaboration. Own the configuration and administration of support systems...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$168K - $181K *

Lead the charge in developing innovative AWS cloud solutions for scoring capabilities. Collaborate with cross-functional teams to enhance system reliability and efficiency, while mentoring junior engi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Advance the future of financial engineering by building a robust platform for pricing, billing, and revenue management in an AI-driven environment. Collaborate cross-functionally to automate processes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$152K - $205K *

Lead the charge in architecting AI-driven solutions for enterprise clients, transforming complex data governance challenges into actionable insights. Collaborate with stakeholders to shape product evo...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$212K - $409K *

Drive innovation as a key member of our engineering team, leveraging your expertise in software engineering and data platforms to shape solutions that enhance customer experiences and meet business go...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Lead the design and delivery of scalable banking features, ensuring reliability and security in real-time money movement. Mentor engineers and collaborate with cross-functional teams to create high-qu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$204K - $264K *

Lead the charge in shaping technical strategy and fostering a culture of quality within your team, ensuring operational excellence and collaboration across product development to drive impactful busin...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.