Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$120K - $145K *

Join a dynamic team to enhance Robotics Operations through innovative software solutions. Collaborate with cross-functional teams to identify needs, deliver impactful improvements, and maintain reliab...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$135K - $160K *

Unlock the potential of NetBox Delivery by leading software design, enhancing production reliability, and mentoring engineers. Shape the technical direction and ensure seamless deployment on Cloud and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$205K - $231K *

Join a team that's redefining software supply chain security. As a Staff Software Engineer, you'll lead backend system design, API development, and cross-team collaboration, driving impactful solution...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Shape the future of autonomous driving by leading trajectory generation and controls. Collaborate across teams to deliver safe, optimized solutions while enhancing vehicle performance through innovati...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$160K - $200K *

Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$192K - $202K *

Lead the technical roadmap and modernize data solutions infrastructure, enhancing off-platform integrations and measurement capabilities while driving AI-first engineering initiatives and cross-team c...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$212K - $265K *

Advance your career by leading the design of scalable insurance systems, collaborating with cross-functional teams to enhance product offerings and drive technical excellence in a dynamic environment...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$188K - $265K *

Accelerate progress at the forefront of AI infrastructure by leading technical direction, ensuring platform architecture meets company ambitions, and fostering collaboration across engineering teams f...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Transform healthcare technology by owning core products, driving architectural decisions, and ensuring high-quality code. Collaborate across teams to deliver impactful solutions that enhance patient c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $254K *

Transform connected systems by designing and deploying advanced anomaly detection models. Lead a team to build robust pipelines, ensuring real-time analysis and integration across AI and engineering t...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Elevate your engineering career by leading innovative projects and driving strategic technology direction in a rapidly growing organization. Collaborate across teams to champion excellence and mentor...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$164K - $262K *

Elevate your career by designing and building self-service cloud APIs and services. Collaborate with teams to transform complex cloud operations into reliable, user-friendly products that enhance deve...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$130K - $155K *

Innovate your career by leading the technical direction of web systems, enhancing product reliability, and mentoring engineers. Embrace AI-first engineering to drive impactful solutions and foster col...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$230K - $270K *

Empower innovation as you lead technical initiatives for multi-tenant platforms, guiding architecture and implementation while collaborating across teams to enhance partner capabilities and ensure ser...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Join a team that's transforming multi-cloud infrastructure. As a Staff Software Engineer, you'll design and build a cohesive platform across AWS, GCP, and Azure, leading a multi-component system while...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$110K - $145K *

Shape the future of healthcare technology by designing and implementing innovative care management tools. Collaborate with teams to create reliable software solutions while mentoring others and advanc...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $167K *

Lead the charge in evolving our cloud infrastructure and CI/CD systems. As a Senior DevOps Engineer, you'll enhance security, reliability, and operational efficiency while mentoring a team and ensurin...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Architect the future of our Builder Platform by leading the design and operation of scalable agent workflows. Collaborate across teams to enhance productivity and drive innovation in AI infrastructure...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$108K - $130K *

Explore a vibrant tech landscape as a Senior Software Engineer, utilizing cutting-edge technologies. Collaborate on innovative solutions, mentor peers, and impact software quality while advocating for...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$112K - $187K *

Join a dynamic team as a Senior Software Engineer, driving innovation in cloud technology. Collaborate across disciplines, mentor peers, and lead impactful projects that enhance our product suite whil...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$217K - $303K *

Lead the charge in shaping the future of our developer platform. Collaborate across backend, platform, and full-stack systems to enhance developer experiences and drive innovation in app development...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Media

$170K - $200K *

Unlock potential by designing and building innovative billing systems that simplify financial transactions and maximize reimbursements, while leveraging AI to enhance efficiency and user experience in...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Champion the development of scalable, cloud-native applications, enhancing data pipelines and integrations. Collaborate with teams to transform raw data into actionable insights, driving improvements...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$265K - $279K *

Join our team to lead and innovate our data infrastructure, owning the architecture and governance of our open lakehouse. Collaborate cross-functionally, tackle complex challenges, and enhance enginee...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$240K - $260K *

Join a team that's redefining restaurant ordering systems. As a Staff Engineer, you'll architect resilient, event-sourced platforms, ensuring reliability and performance across thousands of devices wh...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.